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image of Porcine Cysticercosis: Possible Cross-Reactivity of Taenia hydatigena to GP50 Antigen in the Enzyme-Linked Immunoelectrotransfer Blot Assay
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

The lentil lectin glycoprotein enzyme-linked immunoelectrotransfer blot (LLGP EITB, reported sensitivity 99% and specificity 100%) is used as a serologic marker of exposure to in pigs. However, only a limited number of parasites have been evaluated for cross reactivity. Pigs may host other related cestode infections, including which have not been formally evaluated for cross-reactions. We investigated a corral in Tumbes, Peru, a region where a cysticercosis elimination demonstration project was completed in 2012. In this corral, 14/19 (73.7%) 6–8-week-old piglets were reactive to GP50 on LLGP EITB, and all had circulating sp. antigens. From eight necropsied piglets; four were infected with metacestodes whereas none had evidence of infection. Two resident dogs were subsequently confirmed to have taeniasis. These results suggest GP50 cross-reactivity in infected pigs, although controlled experimental infection is needed to confirm this hypothesis.

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/content/journals/10.4269/ajtmh.17-0378
2017-10-02
2017-11-21
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http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.17-0378
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  • Published online : 02 Oct 2017
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