1921
Volume 96, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract

Latin America is among the highly endemic regions for cystic echinococcosis (CE). In Peru, an estimated 1,139 disability-adjusted life years are lost annually from surgical treatment of CE. This is comparable with the combined total for Argentina, Brazil, Uruguay, and Chile. The prevalence of human infection has been investigated in the central Peruvian Andes, but there are no community-based screening data from other regions of Peru. We carried out a population survey in January 2015 using abdominal ultrasound to estimate the prevalence of abdominal CE in the Canas and Canchis provinces, in the Cusco region of Peru. Among 1,351 subjects screened, 41 (3%) had CE. There was significant variation between communities with similar socioeconomic features in a small geographical area. A history of CE was reported by 4.1% of the screened subjects, among whom 30.3% still had CE on ultrasound. Among patients reporting previous CE treatment, 14.9% had CE in active stages. Limited education, community of residence, and knowing people with CE in the community were associated with CE. These results demonstrate a significant burden of CE in the region and suggest the need for further investigations, control activities, and optimization of clinical management for CE in this area.

Loading

Article metrics loading...

The graphs shown below represent data from March 2017
/content/journals/10.4269/ajtmh.16-0882
2017-03-27
2019-05-23
Loading full text...

Full text loading...

/deliver/fulltext/14761645/96/6/1472.html?itemId=/content/journals/10.4269/ajtmh.16-0882&mimeType=html&fmt=ahah

References

  1. Budke CM, Deplazes P, Torgerson PR, , 2006. Global socioeconomic impact of cystic echinococcosis. Emerg Infect Dis 12: 296303.[Crossref] [Google Scholar]
  2. Craig P, Budke C, Schantz P, Li T, Qiu J, Yang Y, Zeyhle E, Togan M, Ito A, , 2007. Human echinococcosis: a neglected disease? Trop Med Health 35: 283292.[Crossref] [Google Scholar]
  3. Martinez P, , 2014. Characterization of human hydatidosis mortality: Chile, 2000–2010 [in Spanish]. Rev Chilena Infectol 31: 715.[Crossref] [Google Scholar]
  4. Moro PL, Budke CM, Schantz PM, Vasquez J, Santivanez SJ, Villavicencio J, , 2011. Economic impact of cystic echinococcosis in Peru. PLoS Negl Trop Dis 5: e1179.[Crossref] [Google Scholar]
  5. Gavidia CM, Gonzalez AE, Zhang W, McManus DP, Lopera L, Ninaquispe B, Garcia HH, Rodriguez S, Verastegui M, Calderon C, Pan WK, Gilman RH, , 2008. Diagnosis of cystic echinococcosis, central Peruvian Highlands. Emerg Infect Dis 14: 260266.[Crossref] [Google Scholar]
  6. Moro PL, Bonifacio N, Gilman RH, Lopera L, Silva B, Takumoto R, Verastegui M, Cabrera L, , 1999. Field diagnosis of Echinococcus granulosus infection among intermediate and definitive hosts in an endemic focus of human cystic echinococcosis. Trans R Soc Trop Med Hyg 93: 611615.[Crossref] [Google Scholar]
  7. Moro PL, Garcia HH, Gonzales AE, Bonilla JJ, Verastegui M, Gilman RH, , 2005. Screening for cystic echinococcosis in an endemic region of Peru using portable ultrasonography and the enzyme-linked immunoelectrotransfer blot (EITB) assay. Parasitol Res 96: 242246.[Crossref] [Google Scholar]
  8. Moro PL, McDonald J, Gilman RH, Silva B, Verastegui M, Malqui V, Lescano G, Falcon N, Montes G, Bazalar H, , 1997. Epidemiology of Echinococcus granulosus infection in the central Peruvian Andes. Bull World Health Organ 75: 553561. [Google Scholar]
  9. Santivanez SJ, Naquira C, Gavidia CM, Tello L, Hernandez E, Brunetti E, Kachani M, Gonzalez AE, Garcia HH, , 2010. Household factors associated with the presence of human hydatid disease in three rural communities of Junin, Peru [in Spanish]. Rev Peru Med Exp Salud Publica 27: 498505.[Crossref] [Google Scholar]
  10. Romani EL, Rodrigues-Silva R, Maldonado A, Jr Machado-Silva JR, Gomes DC, , 2006. Notes on human cases of cystic echinococcosis in Peru. Mem Inst Oswaldo Cruz 101: 335337.[Crossref] [Google Scholar]
  11. Sanchez E, Caceres O, Naquira C, Garcia D, Patino G, Silvia H, Volotao AC, Fernandes O, , 2010. Molecular characterization of Echinococcus granulosus from Peru by sequencing of the mitochondrial cytochrome C oxidase subunit 1 gene. Mem Inst Oswaldo Cruz 105: 806810.[Crossref] [Google Scholar]
  12. INEI-Peru. Available at: https://www.inei.gob.pe/media/MenuRecursivo/publicaciones_digitales/Est/Lib1261/Libro.pdf. Accessed August 2016.
  13. Brunetti E, Kern P, Vuitton DA, Writing Panel for the WHO-IWGE; , 2010. Expert consensus for the diagnosis and treatment of cystic and alveolar echinococcosis in humans. Acta Trop 114: 116.[Crossref] [Google Scholar]
  14. Beard TC, , 1978. Evidence that a hydatid cyst is seldom “as old as the patient.” Lancet 2: 3032.[Crossref] [Google Scholar]
  15. Hosch W, Junghanss T, Stojkovic M, Brunetti E, Heye T, Kauffmann GW, Hull WE, , 2008. Metabolic viability assessment of cystic echinococcosis using high-field 1H MRS of cyst contents. NMR Biomed 21: 734754.[Crossref] [Google Scholar]
  16. Piccoli L, Tamarozzi F, Cattaneo F, Mariconti M, Filice C, Bruno A, Brunetti E, , 2014. Long-term sonographic and serological follow-up of inactive echinococcal cysts of the liver: hints for a “watch-and-wait” approach. PLoS Negl Trop Dis 8: e3057.[Crossref] [Google Scholar]
  17. Guarnera EA, Parra A, Kamenetzky L, Garcia G, Gutierrez A, , 2004. Cystic echinococcosis in Argentina: evolution of metacestode and clinical expression in various Echinococcus granulosus strains. Acta Trop 92: 153159.[Crossref] [Google Scholar]
  18. Li T, Ito A, Pengcuo R, Sako Y, Chen X, Qiu D, Xiao N, Craig PS, , 2011. Post-treatment follow-up study of abdominal cystic echinococcosis in Tibetan communities of north west Sichuan Province, China. PLoS Negl Trop Dis 5: e1364.[Crossref] [Google Scholar]
  19. Chebli H, Laamrani El Idrissi A, Benazzouz M, Lmimouni BE, Nhammi H, Elbandouni M, Youbi M, Afifi R, Tahiri S, Essayd El Feydi A, Settaf A, Tinelli C, De Silvestri A, Bouhout S, Abela-Ridder A, Magnino S, Brunetti E, Filice C, Tamarozzi F, , 2017. Human cystic echinococcosis in Morocco: ultrasound screening in the Mid Atlas through an Italian-Moroccan partnership. PLoS Negl Trop Dis 11: e0005384.[Crossref] [Google Scholar]
  20. Larrieu E, Del Carpio M, Salvitti JC, Mercapide C, Sustersic J, Panomarenko H, Costa M, Bigatti R, Labanchi J, Herrero E, Cantoni G, Perez A, Odriozola M, , 2004. Ultrasonographic diagnosis and medical treatment of human cystic echinococcosis in asymptomatic school age carriers: 5 years of follow-up. Acta Trop 91: 513.[Crossref] [Google Scholar]
http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.16-0882
Loading
/content/journals/10.4269/ajtmh.16-0882
Loading

Data & Media loading...

  • Received : 08 Nov 2016
  • Accepted : 12 Feb 2017
  • Published online : 27 Mar 2017

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error