image of Molecular Identification of Onchocerca spp. Larvae in Simulium damnosum sensu lato Collected in Northern Uganda
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


Previous studies have demonstrated that the presence of larvae of other filarial species in sensu lato can distort estimates of transmission potential for in West Africa. However, studies conducted in foci of onchocerciasis in West Central Uganda indicated that larvae other than were not common in vectors collected there. Recent data collected in Northern Uganda revealed a striking discordance between estimates of the prevalence of flies carrying infective larvae obtained from molecular pool screening and dissection methods. To resolve this discrepancy, sequences from three mitochondrially encoded genes were analyzed from the larvae collected by dissection. All larvae analyzed were v. Siisa, a parasite of cattle, or , a parasite of warthogs. These results suggest that nonhuman parasite larvae are common in vectors in Northern Uganda, underscoring the necessity for molecular identification methods to accurately estimate transmission.


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  • Received : 30 Jun 2013
  • Accepted : 17 Aug 2014
  • Published online : 02 Oct 2017
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