1921
Volume 96, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract

Orbital biopsy of nonspecific orbital inflammation, commonly referred to as “orbital pseudotumor,” typically shows a combination of polyclonal lymphocytes, plasmocytes, leukocytes, macrophages, and variable degrees of collagen deposition. Herein, we report a patient with a positive history of mucocutaneous leishmaniasis who presented with an orbital mass with a histological profile of idiopathic orbital inflammation. Immunohistochemical and molecular analysis of the orbital specimens demonstrated that the orbital inflammation was associated with the presence of antigens of and DNA from the parasite.

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/content/journals/10.4269/ajtmh.16-0389
2017-01-11
2018-09-23
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References

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  7. David CV, Craft N, , 2009. Cutaneous and mucocutaneous leishmaniasis. Dermatol Ther (Heidelb) 22: 491502.[Crossref]
  8. Alves-Ferreira EV, Toledo JS, De Oliveira AH, Ferreira TR, Ruy PC, Pinzan CF, Santos RF, Boaventura V, Rojo D, López-Gonzálvez Á, Rosa JC, Barbas C, Barral-Netto M, Barral A, Cruz AK, , 2015. Differential gene expression and infection profiles of cutaneous and mucosal Leishmania braziliensis isolates from the same patient. PLoS Negl Trop Dis 9: e0004018.[Crossref]
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Supplementary Data

Supplemental File

  • Received : 16 May 2016
  • Accepted : 11 Sep 2016

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