Volume 96, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



A 30-year-old male, from a subtropical region of Ecuador, was hospitalized with a 5-year history of persistent cough with rusty brown sputum, chest pain, and progressive dyspnea. The patient underwent thoracic surgery 3 years ago for pleural effusion and subsequently received a 9-month regimen treatment of tuberculosis. However, there was no clinical resolution and symptoms became progressively worse. A chest radiograph and computerized tomography scan showed several small nodules in both lungs. Eggs of spp. were observed in sputum smears, but the smears were negative for acid-fast bacilli. Molecular characterization of eggs by the internal transcribed spacer-2 regions identified them as . The patient was treated with praziquantel and tested negative parasitologically for 12 months. There was clinical resolution of the cough and expectoration, but dyspnea and chest pain persisted.


Article metrics loading...

The graphs shown below represent data from March 2017
Loading full text...

Full text loading...



  1. Daumerie D, Savioli L, Crompton D, Peters P, , 2010. Working to Overcome the Global Impact of Neglected Tropical Diseases: First WHO Report on Neglected Tropical Diseases. Geneva, Switzerland: World Health Organization. [Google Scholar]
  2. Calvopina M, Romero D, Castañeda B, Hashiguchi Y, Sugiyama H, , 2014. Current status of Paragonimus and paragonimiasis in Ecuador. Mem Inst Oswaldo Cruz 109: 849855.[Crossref] [Google Scholar]
  3. Acha P, Szyfres B, , 2003. Paragonimiasis. Zoonosis y Enfermedades Transmisibles Comunes al Hombre y a los Animales: Parasitosis, 3rd edition, Volume 3. Washington, DC: Pan American Health Organization, 158164. [Google Scholar]
  4. Shim YS, Cho SY, Han YC, , 1991. Pulmonary paragonimiasis: a Korean perspective. Semin Respir Crit Care Med 12: 3545.[Crossref] [Google Scholar]
  5. Im JG, Whang HY, Kim WS, Han MC, Shim YS, Cho SY, , 1992. Pleuropulmonary paragonimiasis: radiologic findings in 71 patients. Am J Roentgenol 159: 3943.[Crossref] [Google Scholar]
  6. Zhong HL, Chung HL, He LY, Ho LY, Xu ZB, Hsu CP, Cao WJ, Tsao WC, , 1981. Recent progress in studies of Paragonimus and paragonimiasis control in China. Chin Med J (Engl) 94: 483494. [Google Scholar]
  7. Peñafiel W, Dávalos R, Coloma M, , 1981. Paragonimiasis pulmonar. Revisión clínica de 92 casos. Rev Fac Cienc Med 6: 253261. [Google Scholar]
  8. Singh TS, Mutum SS, Razaque MA, , 1986. Pulmonary paragonimiasis: clinical features, diagnosis and treatment of 39 cases in Manipur. Trans R Soc Trop Med Hyg 80: 967971.[Crossref] [Google Scholar]
  9. Sugiyama H, Singh TS, Rangsiruji A, Dongyou L, , 2013. Paragonimus. , ed. Molecular Detection of Human Parasitic Pathogens. Boca Raton, FL: CRC Press, 423436. [Google Scholar]
  10. Díaz G, Calvopina M, Guderian R, Amunárriz M, , 1991. Control de la Paragonimiasis en el Ecuador. Boletín Epidemiológico. Programa de Enfermedades Tropicales. Quito, Ecuador: Ministerio de Salud Pública, 118. [Google Scholar]
  11. Gómez-Seco J, Rodríguez-Guzmán MJ, Rodríguez-Nieto MJ, Gómez-Escolar PF, Presa-Abos T, Fortes-Alen J, , 2011. Pulmonary paragonimiasis. Arch Bronconeumol 47: 610612.[Crossref] [Google Scholar]
  12. Lall M, Sahni AK, Rajput AK, , 2013. Pleuropulmonary paragonimiasis: mimicker of tuberculosis. Pathog Glob Health 107: 4042.[Crossref] [Google Scholar]
  13. Ministerio de Salud Pública del Ecuador, 2010. Manual de Normas y Procedimientos para el Control de la Tuberculosis. Quito, Ecuador: Ministerio de Salud Pública, 1336. [Google Scholar]
  14. Kim TS, Han J, Shim SS, Jeon K, Koh WJ, Lee I, Lee KS, Kwon OJ, , 2005. Pleuropulmonary paragonimiasis: CT findings in 31 patients. Am J Roentgenol 185: 616621.[Crossref] [Google Scholar]
  15. Slesak G, Inthalad S, Basy P, Keomanivong D, Phoutsavath O, Khampoui S, Grosrenaud A, Amstutz V, Barennes H, Buisson Y, Odermatt P, , 2011. Ziehl-Neelsen staining technique can diagnose paragonimiasis. PLoS Negl Trop Dis 5: 18.[Crossref] [Google Scholar]
  16. Consejo Nacional de Salud, 2014. Cuadro Nacional de Medicamentos Básicos y Registro Terapéutico, 9th edition. Quito, Ecuador: Ministerio de Salud Pública, 586. [Google Scholar]

Data & Media loading...

  • Received : 02 May 2016
  • Accepted : 22 Sep 2016
  • Published online : 11 Jan 2017

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error