1921
Volume 95, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract

This article describes the design and evaluation of AutoSyP, a low-cost, low-power syringe pump intended to deliver intravenous (IV) infusions in low-resource hospitals. A constant-force spring within the device provides mechanical energy to depress the syringe plunger. As a result, the device can run on rechargeable battery power for 66 hours, a critical feature for low-resource settings where the power grid may be unreliable. The device is designed to be used with 5- to 60-mL syringes and can deliver fluids at flow rates ranging from 3 to 60 mL/hour. The cost of goods to build one AutoSyP device is approximately $500. AutoSyP was tested in a laboratory setting and in a pilot clinical study. Laboratory accuracy was within 4% of the programmed flow rate. The device was used to deliver fluid to 10 healthy adult volunteers and 30 infants requiring IV fluid therapy at Queen Elizabeth Central Hospital in Blantyre, Malawi. The device delivered fluid with an average mean flow rate error of −2.3% ± 1.9% for flow rates ranging from 3 to 60 mL/hour. AutoSyP has the potential to improve the accuracy and safety of IV fluid delivery in low-resource settings.

[open-access] This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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2016-10-05
2017-11-18
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References

  1. Lawn JE, Cousens S, Zupan J, , 2005. 4 million neonatal deaths: When? Where? Why? Lancet 365: 891900.[Crossref]
  2. March of Dimes, PMNCH, Save the Children, World Health Organization, 2012. Born Too Soon: The Global Action Report on Preterm Birth. Available at: http://www.who.int/pmnch/media/news/2012/201204_borntoosoon-report.pdf. Accessed September 28, 2015.
  3. Graz B, Dicko M, Willcox ML, Lambert B, Falquet J, Forster M, Giani S, Diakite C, Dembele EM, Diallo D, Barennes H, , 2008. Sublingual sugar for hypoglycaemia in children with severe malaria: a pilot clinical study. Malar J 7: 242.[Crossref]
  4. World Health Organization (WHO), 2015. Interagency List of Medical Devices for Essential Interventions for Reproductive, Maternal, Newborn and Child Health. Geneva, Switzerland: World Health Organization Press.
  5. Lawn JE, Cousens S, Darmstadt GL, Bhutta ZA, Martines J, Paul V, Knippenberg R, Fogstad H, , 2006. 1 year after The Lancet Neonatal Survival Series: was the call for action heard? Lancet 367: 15411547.[Crossref]
  6. U.S. Food and Drug Administration Center for Devices and Radiological Health, 2010. White Paper: Infusion Pump Improvement Initiative. Available at: http://www.fda.gov/downloads/MedicalDevices/ProductsandMedicalProcedures/GeneralHospitalDevicesandSupplies/InfusionPumps/UCM206189.pdf. Accessed September 28, 2015.
  7. Slusher T, Vaucher Y, Zamora T, Curtis B, , 2012. Feeding and Fluids in the Premature and Sick Newborns in the Low-Middle Income Countries. Available at: http://cdn.intechopen.com/pdfs-wm/31650.pdf. Accessed October 15, 2015.
  8. Johnson N, Weisgerber MC, , 2008. Pediatric Fluids and Electrolytes: A Self-Study Text, 4th edition. Milwaukee, WI: Maxishare.
  9. Almroth S, Latham MC, , 1995. Rational home management of diarrhea. Lancet 345: 709711.[Crossref]
  10. Capes D, Martin K, Underwood R, , 1997. Performance of restrictive flow device and an electronic syringe driver for continuous subcutaneous infusion. J Pain Symptom Manage 14: 4.[Crossref]
  11. Mundle S, Regi A, Easterling T, Biswas B, Bracken H, Shekhavat DR, Durocher J, Winikoff B, , 2012. Treatment approaches for preeclampsia in low-resource settings: a randomized trial of the Springfusor pump for delivery of magnesium sulfate. Pregnancy Hypertens 2: 3238.
  12. Association for the Advancement of Medical Instrumentation, 2004. AAMI Standards and Recommended Practices. Arlington, VA: Association for the Advancement of Medical Instrumentation.
  13. International Electrotechnical Commission, 2012. IEC 60601-2-24: Medical Electrical Equipment—Part2–24: Particular Requirements for the Basic Safety and Essential Performance of Infusion Pumps and Controllers. Geneva, Switzerland: International Electrotechnical Commission.
  14. Technical Committee ISO/TC 76, 2010. ISO 28620: Medical Devices—Non-Electrically Driven Portable Infusion Devices. Geneva, Switzerland: International Organization for Standardization.
  15. Smiths Medical, 2013. Medfusion Syringe Pump Model 3500 Operator's Manual. Available at: http://www.medfusionpump.com/assets/literature/manuals/Operators_Manual_3500_40-6370-01A.pdf. Accessed October 15, 2015.
  16. CardinalHealth, 2006. Alaris PK Syringe Pump Directions for Use—English. Available at: http://www.frankshospitalworkshop.com/equipment/documents/infusion_pumps/user_manuals/Alaris%20PK%20-%20User%20manual.pdf. Accessed October 20, 2015.
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  • Received : 12 Apr 2016
  • Accepted : 25 May 2016

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