1921
Volume 96, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract

Dengue fever is the most common arbovirus disease, and presents with a large spectrum of clinical manifestations ranging from asymptomatic disease through to the development of dengue hemorrhagic fever. These extreme cases can lead to dengue shock syndrome, and sometimes death. Spinal cord involvement in dengue virus (DENV) infections is rare. Here, we report a case in which the patient developed acute transverse myelitis (TM) without paraparesis following a DENV infection. This case highlights the importance of physicians' awareness of the possible link between DENV and TM in endemic areas.

Loading

Article metrics loading...

The graphs shown below represent data from March 2017
/content/journals/10.4269/ajtmh.16-0284
2017-02-08
2018-12-14
Loading full text...

Full text loading...

/deliver/fulltext/14761645/96/2/380.html?itemId=/content/journals/10.4269/ajtmh.16-0284&mimeType=html&fmt=ahah

References

  1. Brady OJ, Gething PW, Bhatt S, Messina JP, Brownstein JS, Hoen AG, Moyes CL, Farlow AW, Scott TW, Hay SI, , 2012. Refining the global spatial limits of dengue virus transmission by evidence-based consensus. PLoS Negl Trop Dis 6: e1760.[Crossref] [Google Scholar]
  2. Wilder-Smith A, Byass P, , 2016. The elusive global burden of dengue. Lancet Infect Dis 16: 629631.[Crossref] [Google Scholar]
  3. Achee NL, Gould F, Perkins TA, Reiner RC, Jr Morrison AC, Ritchie SA, Gubler DJ, Teyssou R, Scott TW, , 2015. A critical assessment of vector control for dengue prevention. PLoS Negl Trop Dis 9: e0003655.[Crossref] [Google Scholar]
  4. Chawla P, Yadav A, Chawla V, , 2014. Clinical implications and treatment of dengue. Asian Pac J Trop Med 7: 169178.[Crossref] [Google Scholar]
  5. Chanthamat N, Sathirapanya P, , 2010. Acute transverse myelitis associated with dengue viral infection. J Spinal Cord Med 33: 425427.[Crossref] [Google Scholar]
  6. Thisyakorn U, Thisyakorn C, , 2015. Dengue with central nervous system involvement. Southeast Asian J Trop Med Public Health 46 (Suppl 1): 118122. [Google Scholar]
  7. Verma R, Sahu R, Holla V, , 2014. Neurological manifestations of dengue infection: a review. J Neurol Sci 346: 2634.[Crossref] [Google Scholar]
  8. Kunishige M, Mitsui T, Tan BH, Leong HN, Takasaki T, Kurane I, Mihara A, Matsumoto T, , 2004. Preferential gray matter involvement in dengue myelitis. Neurology 63: 19801981.[Crossref] [Google Scholar]
  9. Leao RN, Oikawa T, Rosa ES, Yamaki JT, Rodrigues SG, Vasconcelos HB, Sousa MR, Tsukimata JK, Azevedo RS, Vasconcelos PF, , 2002. Isolation of dengue 2 virus from a patient with central nervous system involvement (transverse myelitis). Rev Soc Bras Med Trop 35: 401404.[Crossref] [Google Scholar]
  10. Seet RC, Lim EC, Wilder-Smith EP, , 2006. Acute transverse myelitis following dengue virus infection. J Clin Virol 35: 310312.[Crossref] [Google Scholar]
  11. Figueiredo LT, , 2007. Emergent arboviruses in Brazil. Rev Soc Bras Med Trop 40: 224229.[Crossref] [Google Scholar]
  12. Sampathkumar P, Sanchez JL, , 2016. Zika virus in the Americas: a review for clinicians. Mayo Clin Proc 91: 514521.[Crossref] [Google Scholar]
  13. An J, Zhou DS, Kawasaki K, Yasui K, , 2003. The pathogenesis of spinal cord involvement in dengue virus infection. Virchows Arch 442: 472481. [Google Scholar]
  14. Weeratunga PN, Caldera MC, Gooneratne IK, Gamage R, Perera P, , 2014. Neurological manifestations of dengue: a cross sectional study. Travel Med Infect Dis 12: 189193.[Crossref] [Google Scholar]
  15. Miranda de Sousa A, Puccioni-Sohler M, Dias Borges A, Fernandes Adorno L, Papais Alvarenga M, Papais Alvarenga RM, , 2006. Post-dengue neuromyelitis optica: case report of a Japanese-descendent Brazilian child. J Infect Chemother 12: 396398.[Crossref] [Google Scholar]
  16. Misra UK, Kalita J, Mani VE, Chauhan PS, Kumar P, , 2015. Central nervous system and muscle involvement in dengue patients: a study from a tertiary care center. J Clin Virol 72: 146151.[Crossref] [Google Scholar]
  17. de Sousa AM, Alvarenga MP, Alvarenga RM, , 2014. A cluster of transverse myelitis following dengue virus infection in the Brazilian Amazon region. Trop Med Health 42: 115120.[Crossref] [Google Scholar]
  18. Scott TF, Frohman EM, De Seze J, Gronseth GS, Weinshenker BG, Therapeutics and Technology Assessment Subcommittee of American Academy of Neurology, , 2011. Evidence-based guideline: clinical evaluation and treatment of transverse myelitis: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology 77: 21282134.[Crossref] [Google Scholar]
http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.16-0284
Loading
/content/journals/10.4269/ajtmh.16-0284
Loading

Data & Media loading...

  • Received : 12 Apr 2016
  • Accepted : 02 Sep 2016

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error