1921
Volume 95, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract

Safe and effective antimalarial drugs are required for the treatment of pregnant women. We report a 3-day regimen of artesunate (4 mg/kg/day)–azithromycin (25 mg/kg/day) (ASAZ) to be efficacious (polymerase chain reaction–corrected cure rate of 96.7%) and well tolerated in the treatment of malaria in children ( = 11) and adults ( = 19), in Vietnam in 2010. In comparison, the cure rate for artesunate (4 mg/kg on day 0, 2 mg/kg on days 1–6) was 90.0% in children ( = 7) and adults ( = 23). Because azithromycin is considered safe in pregnancy, our findings provide further evidence that ASAZ should be evaluated for the treatment of pregnant women with malaria.

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2016-07-06
2017-09-19
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  • Received : 25 Feb 2016
  • Accepted : 04 Apr 2016

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