Volume 95, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Spontaneous rupture of the spleen is rarely described as a complication of scrub typhus infection. We report a previously healthy 74-year-old Thai female farmer who presented in Nakhon Ratchasima, Thailand, with a history of fever and malaise for 5 days, followed by abdominal pain for 1 day. An exploratory laparotomy was performed due to peritonitis. Operative findings revealed a ruptured spleen and hemoperitoneum. A splenectomy was performed afterward. Scrub typhus was confirmed by a 4-fold increase of IgM titer using an indirect immunofluorescence antibody assay and a positive result from the polymerase chain reaction targeting the 47- and 56-kDa genes in . She responded well to intravenous chloramphenicol and defervesced within 24 hours without any complication.


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  • Received : 05 Feb 2016
  • Accepted : 27 Jul 2016
  • Published online : 07 Dec 2016

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