1921
Volume 95, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract

We estimated the seroprevalence and determined the frequency of acute infections with , spotted fever group rickettsiae, , and among 2,225 febrile patients presenting to community hospitals in three rural Thailand provinces during 2002–2005. The seroprevalence was 0.2% for sennetsu neorickettsiosis (SN), 0.8% for spotted fever group (SFG) rickettsiae, 4.2% for murine typhus (MT), and 4.2% for scrub typhus (ST). The frequency of acute infections was 0.1% for SN, 0.6% for SFG, 2.2% for MT, and 1.5% for ST. Additional studies to confirm the distribution of these pathogens and to identify animal reservoirs and transmission cycles are needed to understand the risk of infection.

[open-access] This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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References

  1. Parola P, Paddock CD, Socolovschi C, Labruna MB, Mediannikov O, Kernif T, Abdad MY, Stenos J, Bitam I, Fournier PE, Raoult D, , 2013. Update on tick-borne rickettsioses around the world: a geographic approach. Clin Microbiol Rev 26: 657702.[Crossref] [Google Scholar]
  2. Acestor N, Cooksey R, Newton PN, Menard D, Guerin PJ, Nakagawa J, Christophel E, Gonzalez IJ, Bell D, , 2012. Mapping the aetiology of non-malarial febrile illness in southeast Asia through a systematic review—terra incognita impairing treatment policies. PLoS One 7: e44269.[Crossref] [Google Scholar]
  3. Takada N, Fujita H, Kawabata H, Ando S, Sakata A, Takano A, Chaithong U, , 2009. Spotted fever group Rickettsia sp. closely related to Rickettsia japonica, Thailand. Emerg Infect Dis 15: 610611. [Google Scholar]
  4. Parola P, Cornet JP, Sanogo YO, Miller RS, Thien HV, Gonzalez JP, Raoult D, Telford IS, Wongsrichanalai C, , 2003. Detection of Ehrlichia spp., Anaplasma spp., Rickettsia spp., and other eubacteria in ticks from the Thai–Myanmar border and Vietnam. J Clin Microbiol 41: 16001608.[Crossref] [Google Scholar]
  5. The Center for Food Security and Public Health, 2012. Spotted Fevers (Including Rocky Mountain Spotted Fever and Mediterranean Spotted Fever). Available at: http://www.cfsph.iastate.edu/Factsheets/pdfs/RMSF.pdf. Accessed January 24, 2016. [Google Scholar]
  6. Kollars TM, Jr Tippayachai B, Bodhidatta D, , 2001. Short report: Thai tick typhus, Rickettsia honei, and a unique Rickettsia detected in Ixodes granulatus (Ixodidae: Acari) from Thailand. Am J Trop Med Hyg 65: 535537. [Google Scholar]
  7. Sirisanthana T, Pinyopornpanit V, Sirisanthana V, Strickman D, Kelly DJ, Dasch GA, , 1994. First cases of spotted fever group rickettsiosis in Thailand. Am J Trop Med Hyg 50: 682686. [Google Scholar]
  8. Edouard S, Bhengsri S, Dowell SF, Watt G, Parola P, Raoult D, , 2014. Two human cases of Rickettsia felis infection, Thailand. Emerg Infect Dis 20: 17801781.[Crossref] [Google Scholar]
  9. Parola P, Miller RS, McDaniel P, Telford SR, 3rd Rolain JM, Wongsrichanalai C, Raoult D, , 2003. Emerging rickettsioses of the Thai–Myanmar border. Emerg Infect Dis 9: 592595.[Crossref] [Google Scholar]
  10. Sangkasuwan V, Chatyingmongkol T, Sukwit S, Eamsila C, Chuenchitra T, Rodkvamtook W, Jiang J, Richards AL, Lerdthusnee K, Jones JW, , 2007. Description of the first reported human case of spotted fever group rickettsiosis in urban Bangkok. Am J Trop Med Hyg 77: 891892. [Google Scholar]
  11. Botelho-Nevers E, Raoult D, , 2007. Fever of unknown origin due to rickettsioses. Infect Dis Clin North Am 21: 9971011, ix.[Crossref] [Google Scholar]
  12. Vaughan JA, Azad AF, , 1990. Acquisition of murine typhus rickettsiae by fleas. Ann N Y Acad Sci 590: 7075.[Crossref] [Google Scholar]
  13. Phongmany S, Rolain JM, Phetsouvanh R, Blacksell SD, Soukkhaseum V, Rasachack B, Phiasakha K, Soukkhaseum S, Frichithavong K, Chu V, Keolouangkhot V, Martinez-Aussel B, Chang K, Darasavath C, Rattanavong O, Sisouphone S, Mayxay M, Vidamaly S, Parola P, Thammavong C, Heuangvongsy M, Syhavong B, Raoult D, White NJ, Newton PN, , 2006. Rickettsial infections and fever, Vientiane, Laos. Emerg Infect Dis 12: 256262.[Crossref] [Google Scholar]
  14. Angelakis E, Botelho E, Socolovschi C, Sobas CR, Piketty C, Parola P, Raoult D, , 2010. Murine typhus as a cause of fever in travelers from Tunisia and Mediterranean areas. J Travel Med 17: 310315.[Crossref] [Google Scholar]
  15. Silpapojakul K, Varachit B, Silpapojakul K, , 2004. Paediatric scrub typhus in Thailand: a study of 73 confirmed cases. Trans R Soc Trop Med Hyg 98: 354359.[Crossref] [Google Scholar]
  16. Civen R, Ngo V, , 2008. Murine typhus: an unrecognized suburban vectorborne disease. Clin Infect Dis 46: 913918.[Crossref] [Google Scholar]
  17. Watt G, Parola P, , 2003. Scrub typhus and tropical rickettsioses. Curr Opin Infect Dis 16: 429436.[Crossref] [Google Scholar]
  18. Wang CC, Liu SF, Liu JW, Chung YH, Su MC, Lin MC, , 2007. Acute respiratory distress syndrome in scrub typhus. Am J Trop Med Hyg 76: 11481152. [Google Scholar]
  19. Fukuda T, Kitao T, Keida Y, , 1954. Studies of the causative agent of “hyuganetsu” disease. 1. Isolation of the agent and its inoculation trial in human being. Med Biol 32: 200209. [Google Scholar]
  20. Newton PN, Rolain JM, Rasachak B, Mayxay M, Vathanatham K, Seng P, Phetsouvanh R, Thammavong T, Zahidi J, Suputtamongkol Y, Syhavong B, Raoult D, , 2009. Sennetsu neorickettsiosis: a probable fish-borne cause of fever rediscovered in Laos. Am J Trop Med Hyg 81: 190194. [Google Scholar]
  21. Dittrich S, Phuklia W, Turner GD, Rattanavong S, Chansamouth V, Dumler SJ, Ferguson DJ, Paris DH, Newton PN, , 2015. Neorickettsia sennetsu as a neglected cause of fever in south-east Asia. PLoS Negl Trop Dis 9: e0003908.[Crossref] [Google Scholar]
  22. Walter G, Botelho-Nevers E, Socolovschi C, Raoult D, Parola P, , 2012. Murine typhus in returned travelers: a report of thirty-two cases. Am J Trop Med Hyg 86: 10491053.[Crossref] [Google Scholar]
  23. Suttinont C, Losuwanaluk K, Niwatayakul K, Hoontrakul S, Intaranongpai W, Silpasakorn S, Suwancharoen D, Panlar P, Saisongkorh W, Rolain JM, Raoult D, Suputtamongkol Y, , 2006. Causes of acute, undifferentiated, febrile illness in rural Thailand: results of a prospective observational study. Ann Trop Med Parasitol 100: 363370.[Crossref] [Google Scholar]
  24. Ellis RD, Fukuda MM, McDaniel P, Welch K, Nisalak A, Murray CK, Gray MR, Uthaimongkol N, Buathong N, Sriwichai S, Phasuk R, Yingyuen K, Mathavarat C, Miller RS, , 2006. Causes of fever in adults on the Thai–Myanmar border. Am J Trop Med Hyg 74: 108113. [Google Scholar]
  25. Fukuda T, Sasahara T, Kitao T, , 1962. Studies on the causative agent of Hyagu fever disease [in Japanese]. Jpn J Infect Dis 36: 235241. [Google Scholar]
  26. Blacksell SD, Kantipong P, Watthanaworawit W, Turner C, Tanganuchitcharnchai A, Jintawon S, Laongnuanutit A, Nosten FH, Day NP, Paris DH, Richards AL, , 2015. Underrecognized arthropod-borne and zoonotic pathogens in northern and northwestern Thailand: serological evidence and opportunities for awareness. Vector Borne Zoonotic Dis 15: 285290.[Crossref] [Google Scholar]
  27. Takada N, Fujita H, Yano Y, Huang WH, Khamboonruang C, , 1993. Serosurveys of spotted fever and murine typhus in local residents of Taiwan and Thailand compared with Japan. Southeast Asian J Trop Med Public Health 24: 354356. [Google Scholar]
  28. Frances SP, Eamsila C, Strickman D, , 1997. Antibodies to Orientia tsutsugamushi in soldiers in northeastern Thailand. Southeast Asian J Trop Med Public Health 28: 666668. [Google Scholar]
  29. Aung AK, Spelman DW, Murray RJ, Graves S, , 2014. Rickettsial infections in southeast Asia: implications for local populace and febrile returned travelers. Am J Trop Med Hyg 91: 451460.[Crossref] [Google Scholar]
  30. Pickard AL, McDaniel P, Miller RS, Uthaimongkol N, Buathong N, Murray CK, Telford SR, 3rd Parola P, Wongsrichanalai C, , 2004. A study of febrile illnesses on the Thai–Myanmar border: predictive factors of rickettsioses. Southeast Asian J Trop Med Public Health 35: 657663. [Google Scholar]
  31. Sirisanthana V, Puthanakit T, Sirisanthana T, , 2003. Epidemiologic, clinical and laboratory features of scrub typhus in thirty Thai children. Pediatr Infect Dis J 22: 341345. [Google Scholar]
  32. Durand AM, Kuartei S, Togamae I, Sengebau M, Demma L, Nicholson W, O'Leary M, , 2004. Scrub typhus in the Republic of Palau, Micronesia. Emerg Infect Dis 10: 18381840.[Crossref] [Google Scholar]
  33. Strickman D, Tanskul P, Eamsila C, Kelly DJ, , 1994. Prevalence of antibodies to rickettsiae in the human population of suburban Bangkok. Am J Trop Med Hyg 51: 149153. [Google Scholar]
  34. Chang K, Chen YH, Lee NY, Lee HC, Lin CY, Tsai JJ, Lu PL, Chen TC, Hsieh HC, Lin WR, Lai PC, Chang CM, Wu CJ, Lai CH, Ko WC, , 2012. Murine typhus in southern Taiwan during 1992–2009. Am J Trop Med Hyg 87: 141147.[Crossref] [Google Scholar]
  35. Gikas A, Doukakis S, Pediaditis J, Kastanakis S, Psaroulaki A, Tselentis Y, , 2002. Murine typhus in Greece: epidemiological, clinical, and therapeutic data from 83 cases. Trans R Soc Trop Med Hyg 96: 250253.[Crossref] [Google Scholar]
  36. Jensenius M, Fournier PE, Raoult D, , 2004. Rickettsioses and the international traveler. Clin Infect Dis 39: 14931499.[Crossref] [Google Scholar]
  37. Lai CH, Chang LL, Lin JN, Tsai KH, Hung YC, Kuo LL, Lin HH, Chen YH, , 2014. Human spotted fever group rickettsioses are underappreciated in southern Taiwan, particularly for the species closely-related to Rickettsia felis . PLoS One 9: e95810.[Crossref] [Google Scholar]
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  • Received : 15 Oct 2015
  • Accepted : 24 Mar 2016

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