1921
Volume 95, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract

Malaria is considered to be the most common etiology of fever in sub-Saharan Africa while bacteremias exist but are under assessed. This study aimed to assess bacteremias and malaria in children from urban and rural areas in Gabon. DNA extracts from blood samples of 410 febrile and 60 afebrile children were analyzed using quantitative polymerase chain reaction. spp. was the microorganism most frequently detected in febrile (78.8%, 323/410) and afebrile (13.3%, 8/60) children, ( < 0.001). DNA from one or several bacteria were detected in 15 febrile patients (3.7%) but not in the controls ( = 0.1). This DNA was more frequently detected as co-infections among febrile children tested positive for (4.6%, 15/323) than in those tested negative for (0%, 0/87; = 0.04). The bacteria detected were 2.4% (10/410), 1.7% (7/410), spp. 0.7% (3/410), 0.2% (1/410) and 0.2% (1/410) only in febrile children. , spp., spp., spp., and were not observed. This paper reports the first detection of bacteremia related to in Gabon and shows that malaria decreases in urban areas but not in rural areas. Co-infections in febrile patients are common, highlighting the need to improve fever management strategies in Gabon.

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2016-07-06
2017-09-20
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  • Received : 15 Oct 2015
  • Accepted : 13 Mar 2016

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