1921
Volume 96, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract

Human brucellosis is neglected in southern Ethiopia. Although traditional food processing practices and animal husbandry which increase the risk of brucellosis are common, it has not been properly studied yet. This study was conducted to determine the seroepidemiology of brucellosis among apparently healthy individuals in southern Ethiopia. In the study, blood samples were collected to screen for serum agglutinins reactive to stained antigen of . Standard tube titration was performed for reactive serum to determine the titer of the agglutinin. A structured questionnaire was used to collect data on possible risk factors for brucellosis. The seroprevalence of human brucellosis in this study was found to be 10.6% (95% confidence interval = 7.0, 14.0). Possession of domestic ruminant animals, contact with ruminant animals, and husbandry practices at home were associated with seropositivity. The higher seroprevalence of human brucellosis in the study area needs attention and additional confirmatory investigation.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.15-0702
2017-01-11
2018-08-15
Loading full text...

Full text loading...

/deliver/fulltext/14761645/96/1/88.html?itemId=/content/journals/10.4269/ajtmh.15-0702&mimeType=html&fmt=ahah

References

  1. Pappas G, Papadimitriou P, Akritidis N, Christou L, Tsianos EV, , 2006. The new global map of human brucellosis. Lancet Infect Dis 6: 9199.[Crossref]
  2. Ducrotoy MJ, Bertu WJ, Ocholi RA, Gusi AM, Bryssinckx W, Welburn S, Moriyon I, , 2014. Brucellosis as an emerging threat in developing economies: lessons from Nigeria. PLoS Negl Trop Dis 8: e3008.[Crossref]
  3. Swai ES, Schoonman L, , 2009. Human brucellosis: seroprevalence and risk factors related to high risk occupational groups in Tanga Municipality, Tanzania. Zoonoses Public Health 56: 183187.[Crossref]
  4. Dean AS, Crump L, Greter H, Schelling E, Zinsstag J, , 2012. Global burden of human brucellosis: a systematic review of disease frequency. PLoS Negl Trop Dis 6: e1865.[Crossref]
  5. Yohannes M, Degefu H, Tolosa T, Belihu K, Cutler R, Cutler S, , 2013. Brucellosis in Ethiopia. Afr J Microbiol Res 7: 11501157.[Crossref]
  6. Corbel MJ, , 2006. Brucellosis in Humans and Animals. Geneva, Switzerland: World Health Organization.
  7. Rahman AK, Dirk B, Fretin D, Saegerman C, Ahmed MU, Muhammad N, Hossain A, Abatih E, , 2012. Seroprevalence and risk factors for brucellosis in a high-risk group of individuals in Bangladesh. Foodborne Pathog Dis 9: 190197.[Crossref]
  8. John K, Fitzpatrick J, French N, Kazwala R, Kambarage D, Mfinanga GS, MacMillan A, Cleaveland S, , 2010. Quantifying risk factors for human brucellosis in rural northern Tanzania. PLoS One 5: e9968.[Crossref]
  9. Dean AS, Crump L, Greter H, Hattendorf J, Schelling E, Zinsstag J, , 2012. Clinical manifestations of human brucellosis: a systematic review and meta-analysis. PLoS Negl Trop Dis 6: e1929.[Crossref]
  10. Godfroid J, Scholz HC, Barbier T, Nicolas C, Wattiau P, Fretin D, Whatmore AM, Cloeckaert A, Blasco JM, Moriyon I, Saegerman C, Muma JB, Al Dahouk S, Neubauer H, Letesson JJ, , 2011. Brucellosis at the animal/ecosystem/human interface at the beginning of the 21st century. Prev Vet Med 102: 118131.[Crossref]
  11. Berhe G, Belihu K, Asfaw Y, , 2007. Seroepidemiological investigation of bovine brucellosis in the extensive cattle production system of Tigray Region of Ethiopia. Int J Appl Res Vet Med 5: 6571.
  12. Regassa G, Mekonnen D, Yamuah L, Tilahun H, Guta T, Gebreyohannes A, Aseffa A, Abdoel TH, Smits HL, , 2009. Human brucellosis in traditional pastoral communities in Ethiopia. Int J Trop Med 4: 5964.
  13. Jergefa T, Kelay B, Bekana M, Teshale S, Gustafson H, Kindahl H, , 2009. Epidemiological study of bovine brucellosis in three agro-ecological areas of central Oromiya, Ethiopia. Rev Sci Tech 28: 933943.
  14. Yohannes M, Tesfaye M, Hailu D, Tadele TWM, , 2012. Bovine brucellosis: serological survey in Guto-Gida District, East Wollega Zone, Ethiopia. Global Veterinaria 8: 139143.
  15. Megersa B, Biffa D, Niguse F, Rufael T, Asmare K, Skjerve E, , 2011. Cattle brucellosis in traditional livestock husbandry practice in southern and eastern Ethiopia, and its zoonotic implication. Acta Vet Scand 53: 24.[Crossref]
  16. Haileselassie M, Shewit KKM, , 2010. Serological survey of bovine brucellosis in barka and arado breeds (Bos indicus) of western Tigray, Ethiopia. Prev Vet Med 94: 2835.[Crossref]
  17. Teklue T, Tolosa T, Tuli G, Beyene B, Hailu B, , 2013. Sero-prevalence and risk factors study of brucellosis in small ruminants in Southern Zone of Tigray Region, northern Ethiopia. Trop Anim Health Prod 45: 18091815.[Crossref]
  18. Ibrahim N, Belihu K, Lobago F, Bekana M, , 2010. Sero-prevalence of bovine brucellosis and its risk factors in Jimma zone of Oromia Region, south-western Ethiopia. Trop Anim Health Prod 42: 3540.[Crossref]
  19. Kebede T, Ejeta GGA, , 2008. Seroprevalence of bovine brucellosis in smallholder farms in central Ethiopia (Wuchale-Jida district). Revue Méd Vét 159: 39.
  20. Tibesso G, Ibrahim N, Tolosa T, , 2014. Sero-prevalence of bovine and human brucellosis in Adami Tulu, central Ethiopia. World Appl Sci J 31: 776780.
  21. Kassahun A, Shiv P, Yilkal A, Esayas G, Gelagaye AZA, , 2007. Seroprevalence of brucellosis in cattle and high risk professionals in Sidama Zone, southern Ethiopia. Ethiop Vet J 11: 6984.
  22. Mussie H, Tesfu K, Mulugeta T, Kelay B, Yilkal AAA, , 2007. Seroprevalence of brucellosis in cattle and occupationally related human in selected sites of Ethiopia. Ethiop Vet J 11: 4965.
  23. Kassahun J, Yimer E, Geyid A, Abebe P, Newayeselassie B, Zewdie B, Beyene M, Bekele A, , 2006. Sero-prevalence of brucellosis in occupationally exposed people in Addis Ababa, Ethiopia. Ethiop Med J 44: 245252.
  24. Ghilian R, Hekmati Moghaddam SH, Fatemi A, Eslamieh H, Dargahi M, , 2011. Seroepidemiologic status of brucellosis in blood donors in Yazd, 2009. Sci J Iran Blood Transfus Org 7: 196205.
  25. Tolosa T, Ragassa F, Belihu K, Tizazu G, , 2007. Brucellosis among patients with fever of unknown origin in Jimma University Hospital, southwestern Ethiopia. Ethiop J Health Sci 17: 5964.
  26. Animut A, Mekonnen Y, Shimelis D, Ephraim E, , 2009. Febrile illnesses of different etiology among outpatients in four health centers in northwestern Ethiopia. Jpn J Infect Dis 62: 107110.
  27. Sofian M, Sheikholeslami M, Mahdaviani FA, Aghakhani A, Banifazl M, Eslamifar A, Sarmadian H, Deiri G, Ramezani A, , 2013. Low prevalence of Brucella agglutinins in blood donors in central province of Iran. Iran J Microbiol 5: 2427.
  28. Torres-Padilla JC, Lopez-Merino A, Garcia-Escamilla RM, Gutierrez-Garcia JN, , 2004. Anti-Brucella antibody seroprevalence in blood donors for therapeutic ends at three blood banks of the Mexican Institute of Social Security [in Spanish]. Gac Med Mex 140: 391398.
  29. Asmare K, Asfaw Y, Gelaye E, Ayelet G, , 2010. Brucellosis in extensive management system of Zebu cattle in Sidama Zone, southern Ethiopia. Afr J Agric Res 5: 257263.
  30. Dinka HRC, , 2009. Seroprevalence study of bovine brucellosis in pastoral and agro-pastoral areas of East Showa Zone, Oromia Regional State, Ethiopia. Am Eurasian J Agric Environ Sci 6: 508512.
  31. Tolosa T, Ragassa FKB, , 2008. Seroprevalence study of bovine brucellosis in extensive management system in selected sites of Jimma Zone, western Ethiopia. Bull Anim Health Prod Afr 56: 2537.
  32. Asmare K, Sibhat B, Molla W, Ayelet G, Shiferaw J, Martin AD, Skjerve E, Godfroid J, , 2013. The status of bovine brucellosis in Ethiopia with special emphasis on exotic and cross bred cattle in dairy and breeding farms. Acta Trop 126: 186192.[Crossref]
http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.15-0702
Loading
/content/journals/10.4269/ajtmh.15-0702
Loading

Data & Media loading...

  • Received : 26 Sep 2015
  • Accepted : 11 Oct 2016

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error