Volume 96, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



The Department of Santa Rosa, Guatemala, is targeted for malaria elimination. However, compared with 2011, a 13-fold increase in cases was reported in 2012. To describe the epidemiology of malaria in Santa Rosa in the setting of the apparent outbreak, demographic and microscopic data from 2008 to 2013 were analyzed. In April 2012, a new surveillance strategy, funded by the Global Fund to Fight AIDS, Tuberculosis and Malaria, was introduced involving more active case detection, centralized microscopy, increased community engagement, and expanded vector control. Interviews with vector control personnel and site visits were conducted in June 2013. From 2008 to 2013, 337 cases of malaria were reported. The increase in cases occurred largely after the new surveillance strategy was implemented. Most (137/165; 83%) 2012 cases came from one town near a lake. was the malaria species detected in all cases. Cases were detected where malaria was not previously reported. Monthly rainfall or/and temperature did not correlate with cases. Interviews with public health personnel suggested that the new funding, staffing, and strategy were responsible for improved quality of malaria detection and control and thus the increase in reported cases. Improvements in surveillance, case detection, and funding appear responsible for the temporary increase in cases, which thus may paradoxically indicate progress toward elimination.


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  1. World Health Organization, 2016. World Malaria Report 2015, Summary. Available at: http://who.int/malaria/publications/world-malaria-report-2015/report/en/. Accessed July 31, 2016. [Google Scholar]
  2. World Health Organization, 2016. Eliminating Malaria. Available at: http://www.who.int/malaria/publications/atoz/eliminating-malaria/en/. Accessed July 31, 2016. [Google Scholar]
  3. Tatem AJ, Smith DL, Gething PW, Kabaria CW, Snow RW, Hay SI, , 2010. Ranking of elimination feasibility between malaria-endemic countries. Lancet 376: 15791591.[Crossref] [Google Scholar]
  4. Global Fund, 2013. Ten Countries Rally to Eliminate Malaria in Central America and the Caribbean. Available at: http://reliefweb.int/report/haiti/ten-countries-rally-eliminate-malaria-central-america-and-caribbean. Accessed December 7, 2016. [Google Scholar]
  5. Herrera S, Quiñones ML, Quintero JP, Corredor V, Fuller DO, Mateus JC, Calzada JE, Gutierrez JB, Llanos A, Soto E, Menendez C, Wu Y, Alonso P, Gabriel Carrasquilla G, , 2012. Prospects for malaria elimination in non-Amazonian regions of Latin America. Acta Trop 121: 315323.[Crossref] [Google Scholar]
  6. World Health Organization, 2012. World Malaria Report 2012. Geneva, Switzerland: WHO. Available at: http://who.int/malaria/publications/world-malaria-report-2015/report/en/. [Google Scholar]
  7. Lindblade KA, Arana B, Zea-Flores G, Rizzo N, Porter CH, Dominguez A, Cruz-Ortiz N, Unnasch TR, Punkosdy GA, Richards J, Sauerbrey M, Castro J, Catú E, Oliva O, Richards FO, , 2007. Elimination of Onchocercia volvulus transmission in the Santa Rosa focus of Guatemala. Am J Trop Med Hyg 77: 334341. [Google Scholar]
  8. Yamagata Y, Nakagawa J, , 2006. Control of Chagas disease. Adv Parasitol 61: 129165.[Crossref] [Google Scholar]
  9. World Health Organization, 2008. The Global Malaria Action Plan. Roll Back Malaria Partnership. Available at: http://archiverbm.rollbackmalaria.org/gmap/gmap.pdf. Accessed December 7, 2016. [Google Scholar]
  10. World Health Organization, 2015. Malaria Country Profile: Guatemala. Available at: http://www.who.int/malaria/publications/country-profiles/profile_gtm_en.pdf?ua=1. [Google Scholar]
  11. World Health Organization, 1997. Vector Control. Methods for Use by Individuals and Communities. Available at: http://www.who.int/whopes/resources/vector_rozendaal/en/. Accessed July 31, 2016. [Google Scholar]
  12. PAHO, 2006. Regional Strategic Plan for Malaria in the Americas 2006–2010. Available at: http://publications.paho.org/product.php?productid=914. Accessed July 31, 2016. [Google Scholar]
  13. StataCorp, 2011. Stata Statistical Software: Release 12. College Station, TX: StataCorp LP. [Google Scholar]
  14. Instituto Nacional de Sismologia Vulcanologia Meteorologia e Hidrologia (INSIVUMEH), 2013. Available at: http://www.insivumeh.gob.gt/meteorologia/mapa_estaciones.htm. Accessed June 30, 2013.
  15. ESRI, 2011. ArcGIS Desktop: Release 10.1. Redlands, CA: Environmental Systems Research Institute. [Google Scholar]
  16. CIA, 2013. World Fact Book. Available at: https://www.cia.gov/library/publications/the-world-factbook/. Accessed July 31, 2016. [Google Scholar]
  17. Global Fund. New Funding Model. Available at: http://www.theglobalfund.org/en/fundingmodel/. Accessed July 31, 2016. [Google Scholar]
  18. International Harm Reduction Association, 2014. The Funding Crisis for Harm Reduction: Donor Retreat, Government Neglect and the Way Forward. Available at: http://www.ihra.net/files/2014/09/22/Funding_report_2014.pdf. Accessed July 31, 2016. [Google Scholar]
  19. Cardona PO, , 2012. Área de Salud combate zancudo en laguna El Pino. Prensa Libre (July 16, 2012). [Google Scholar]
  20. Pan American Health Organization, 2007. Guide for Implementation and Demonstration of Sustainable Alternatives for Integrated Control of Malaria in Mexico and Central America. DDT/GEF Project. Atlacomulco, Mexico: PAHO. Available at: www.paho.org/mex/index.php?option=com_docman&task…. [Google Scholar]
  21. Grieco J, Vogtsberger R, Achee N, Vanzie E, Andre RE, Roberts DR, Rejmankova E, , 2005. Evaluation of habitat management strategies for the reduction of malaria vectors in northern Belize. J Vector Ecol 30: 235243. [Google Scholar]
  22. Wikipedia. Tropical Storm Agatha. Available at: https://en.wikipedia.org/wiki/Tropical_Storm_Agatha. Accessed July 31, 2016. [Google Scholar]
  23. Teklehaimanot H, Lipsitch M, Teklehaimanot A, Schwartz J, , 2004. Weather-based prediction of Plasmodium falciparum malaria in epidemic-prone regions of Ethiopia. Patterns of lagged weather effects reflect biological mechanisms. Malar J 3: 41.[Crossref] [Google Scholar]
  24. Grillet ME, El Souki M, Laguna F, Leon JR, , 2014. The periodicity of Plasmodium vivax and Plasmodium falciparum in Venezuela. Acta Tropica 129: 5260.[Crossref] [Google Scholar]
  25. Nájera JA, González-Silva M, Alonso PL, , 2011. Some lessons for the future from the Global Malaria Eradication Programme (1955–1969). PLoS Med 8: e1000412.[Crossref] [Google Scholar]
  26. Takeuchi R, Lawpoolsri S, Imwong M, Kobayashi J, Kaewkungwal J, Pukrittayakamee S, Puangsa-art S, Thanyavanich N, Maneeboonyang W, Day NP, Singhasivanon P, , 2010. Directly-observed therapy (DOT) for the radical 14-day primaquine treatment of Plasmodium vivax malaria on the Thai-Myanmar border. Malar J 9: 308.[Crossref] [Google Scholar]
  27. Grietens KP, Soto V, Erhart A, Ribera JM, Toomer E, Tenorio A, Montalvo TG, Rodriguez H, Cuentas AL, D'Alessandro U, Gamboa D, , 2010. Adherence to 7-day primaquine treatment for the radical cure of P. vivax in the Peruvian Amazon. Am J Trop Med Hyg 82: 10171023.[Crossref] [Google Scholar]

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  • Received : 24 Sep 2015
  • Accepted : 29 Sep 2016
  • Published online : 30 Jan 2017

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