1921
Volume 94, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract

Since the first reported epidemic of dengue in Pemba, the capital of Cabo Delgado province, in 1984–1985, no further cases have been reported in Mozambique. In March 2014, the Provincial Health Directorate of Cabo Delgado reported a suspected dengue outbreak in Pemba, associated with a recent increase in the frequency of patients with nonmalarial febrile illness. An investigation conducted between March and June detected a total of 193 clinically suspected dengue patients in Pemba and Nampula, the capital of neighboring Nampula Province. Dengue virus-type 2 (DENV-2) was detected by reverse transcriptase polymerase chain reaction in sera from three patients, and 97 others were classified as probable cases based on the presence of DENV nonstructural protein 1 antigen or anti-DENV immunoglobulin M antibody. Entomological investigations demonstrated the presence of mosquitos in both Pemba and Nampula cities.

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2016-02-03
2017-11-23
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References

  1. Guzman MG, Halstead SB, Artsob H, Buchy P, Farrar J, Gubler DJ, Hunsperger E, Kroeger A, Margolis HS, Martinez E, Nathan MB, Pelegrino JL, Simmons C, Yoksan S, Peeling RW, , 2010. Dengue: a continuing global threat. Nat Rev Microbiol 8: S7S16.[Crossref]
  2. Bhatt S, Gething PW, Brady OJ, Messina JP, Farlow AW, Moyes CL, Drake JM, Brownstein JS, Hoen AG, Sankoh O, Myers MF, George DB, Jaenisch T, Win GR, Simmons CP, Scot TW, Farrar JJ, Hay SI, , 2013. The global distribution and burden of dengue. Nature 496: 504507.[Crossref]
  3. Guzman A, Isturiz RE, , 2010. Update on the global spread of dengue. Int J Antimicrob Agents 36 (Suppl 1): S40S42.[Crossref]
  4. Brady OJ, Gething PW, Bhatt S, Messina JP, Brownstein JS, Hoen AG, Moyes CL, Farlow AW, Scott TW, Hay SI, , 2012. Refining the global spatial limits of dengue virus transmission by evidence-based consensus. PLoS Negl Trop Dis 6: e1760.[Crossref]
  5. Jaenisch T, Junghanss T, Wills B, Brady OJ, Eckerle I, Farlow A, Hay SI, McCall PJ, Messina JP, Ofula V, Sall AA, Sakuntabhai A, Velayudhan R, Wint W, Zeller H, Margolis HS, Sankoh O, Dengue in Africa Study Group, , 2014. Dengue expansion in Africa-not recognized or not happening? Emerg Infect Dis 20: e140487.[Crossref]
  6. Amarasinghe A, Kuritsk JN, Letson GW, Margolis HS, , 2011. Dengue virus infection in Africa. Emerg Infect Dis 17: 13491354.
  7. CDC, 2013. Ongoing dengue epidemic - Angola, June 2013. MMWR Morb Mortal Wkly Rep 62: 504507.
  8. Johnson BK, Ocheng D, Gichogo A, Okiro M, Libondo D, Kinyanjui P, Tukei PM, , 1982. Epidemic dengue fever caused by dengue type 2 virus in Kenya: preliminary results of human virological and serological studies. East Afr Med J 59: 781784.
  9. Hertz JT, Munishi OM, Ooi EE, Howe S, Lim WY, Chow A, Morissey AB, Bartlett JA, Onyango JJ, Maro VP, Kinabo GD, Saganda W, Gubler DJ, Crump JA, , 2012. Chikungunya and dengue fever among hospitalized febrile patients in northern Tanzania. Am J Trop Med Hyg 86: 171177.[Crossref]
  10. Kanesa-thasan N, Chang GJ, Smoak BL, Magill A, Burrous MJ, Hoke CH, , 1998. Molecular and epidemiologic analysis of dengue virus isolates from Somalia. Emerg Infect Dis 4: 299303.[Crossref]
  11. Gubler DJ, Sather GE, Kuno G, Cabral JR, , 1986. Dengue 3 virus transmission in Africa. Am J Trop Med Hyg 35: 12801284.
  12. Kuno G, Chang GJ, Tsuchiya KR, Karabatsos N, Cropp CB, , 1998. Phylogeny of the genus Flavivirus. J Virol 72: 7383.
  13. Hume JC, Barnish G, Mangal T, Armazio L, Streat E, Bates I, , 2008. Household cost of malaria overdiagnosis in rural Mozambique. Malar J 7: 33.[Crossref]
  14. Barat L, Chipipa J, Kolczak M, Sukwa T, , 1999. Does the availability of blood slide microscopy for malaria at health centers improve the management of persons with fever in Zambia? Am J Trop Med Hyg 60: 10241030.
  15. Messina JP, Brady OJ, Scott TW, Zou C, Pigott DM, Duda KA, Bhatt S, Katzelnick L, Howes RE, Battle KE, Simmons CP, Hay SI, , 2014. Global spread of dengue virus types: mapping the 70 year history. Trends Microbiol 22: 138146.[Crossref]
  16. Chipwaza B, Mugasa JP, Selemani M, Amuri M, Mosha F, Ngatunga SD, Gwakisa PS, , 2014. Dengue and Chikungunya fever among viral diseases in outpatient febrile children in Kilosa district hospital, Tanzania. PLoS Negl Trop Dis 8: e3335.[Crossref]
  17. Higa Y, Abílio AP, Futami K, Lázaro MAF, Minakawa N, Gudo ES, , 2014. Abundant Aedes (Stegomyia) aegypti aegypti mosquitoes in the 2014 dengue outbreak area of Mozambique. Trop Med Health 43: 107109.[Crossref]
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  • Received : 24 Jul 2015
  • Accepted : 12 Oct 2015

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