Volume 94, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



For the first time in 16 years, a food-borne outbreak of typhoid fever due to serotype Typhi was reported in Japan. Seven patients consumed food in an Indian buffet at a restaurant in the center of Tokyo, while one was a Nepali chef in the restaurant, an asymptomatic carrier and the implicated source of this outbreak. The multiple-locus variable-number tandem repeat analysis showed 100% consistency in the genomic sequence for five of the eight cases.

[open-access] This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Article metrics loading...

The graphs shown below represent data from March 2017
Loading full text...

Full text loading...



  1. Basnyat B, Maskey AP, Zimmerman MD, Murdoch DR, , 2005. Enteric (typhoid) fever in travelers. Clin Infect Dis 41: 14671472.[Crossref] [Google Scholar]
  2. Olsen SJ, Bleasdale SC, Magnano AR, Landrigan C, Holland BH, Tauxe RV, Mintz ED, Luby S, , 2003. Outbreaks of typhoid fever in the United States, 1960–99. Epidemiol Infect 130: 1321.[Crossref] [Google Scholar]
  3. Loharikar A, Newton A, Rowley P, Wheeler C, Bruno T, Barillas H, Pruckler J, Theobald L, Lance S, Brown JM, Barzilay EJ, Arvelo W, Mintz E, Fagan R, , 2012. Typhoid fever outbreak associated with frozen mamey pulp imported from Guatemala to the western United States, 2010. Clin Infect Dis 55: 6166.[Crossref] [Google Scholar]
  4. Kawamura M, Shibata M, Takahashi M, Yokoyama K, Matsushita S, Nakama A, Kai A, , 2009. Serovar distribution of Salmonella isolated from domestic and imported cases from 2000 to 2008 in Tokyo. Ann Rep Tokyo Metr Inst Pub Health 60: 3944. Available at: http://www.tokyo-eiken.go.jp/assets/issue/journal/2009/pdf/01-03.pdf. Accessed September 25, 2015. [Google Scholar]
  5. Yoda K, Koiwai K, , 1999. Paratyphoid fever outbreak in Chiba prefecture. Infect Agents Surveill Rept 20. Available at: http://idsc.nih.go.jp/iasr/20/233/dj233a.html. Accessed September 25, 2015. [Google Scholar]
  6. Saito T, Shimada C, Yahata Y, Sunagawa T, Oishi K, Morita M, Izumiya H, Ohnishi M, , 2013. Typhoid fever in 2013. Infect Agents Surveill Rept 39. Available at: http://www.nih.go.jp/niid/ja/typhi-m/typhi-idwrc/4019-idwrc-1339.html. Accessed September 25, 2015. [Google Scholar]
  7. National Institute of Infectious Diseases, 2014. IDWR surveillance data week 52, 2014. Infect Dis Wkly Rept Jpn 16. Available at: http://www0.nih.go.jp/niid/idsc/idwr/IDWR2014/idwr2014-52.pdf. Accessed November 9, 2015. [Google Scholar]
  8. National Institute of Infectious Diseases, 2015. Domestic Typhoid fever due to fresh salad. Infect Agents Surveill Rept 36: 162163. Available at: http://www.nih.go.jp/niid/ja/id/1011-disease-based/ta/typhi/idsc/iasr-in/5886-kj4261.html. Accessed September 25, 2015. [Google Scholar]
  9. Octavia S, Lan R, , 2009. Multiple-locus variable-number tandem repeat analysis of Salmonella enterica serovar Typhi. J Clin Microbiol 47: 23692376.[Crossref] [Google Scholar]
  10. Chiou CS, Wei HL, Mu JJ, Liao YS, Liang SY, Liao CH, Tsao CS, Wang SC, , 2013. Salmonella enterica serovar Typhi variants in long-term carriers. J Clin Microbiol 51: 669672.[Crossref] [Google Scholar]
  11. Kenji H, Haruo W, , 2002. Typhoid fever and Paratyphoid fever. Infect Agents Surveill Rept 5. Available at: http://idsc.nih.go.jp/idwr/kansen/k02_g1/k02_05/k02_05.html. Accessed September 25, 2015. [Google Scholar]

Data & Media loading...

  • Received : 01 Jul 2015
  • Accepted : 12 Oct 2015
  • Published online : 03 Feb 2016

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error