Volume 94, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Information on the infectious causes of undifferentiated acute febrile illness (AFI) in Georgia is essential for effective treatment and prevention. In May 2008, a hospital-based AFI surveillance was initiated at six hospitals in Georgia. Patients aged ≥ 4 years with fever ≥ 38°C for ≥ 48 hours were eligible for surveillance. Blood culture and serologic testing were conducted for spp., spp., West Nile virus (WNV), Crimean–Congo hemorrhagic fever virus, , tick-borne encephalitis virus (TBEV), hantavirus, serovar Typhi ( Typhi), and . Of 537 subjects enrolled, 70% were outpatients, 54% were males, and the mean age was 37 years. Patients reported having fatigue (89%), rigors (87%), sweating (83%), pain in joints (49%), and sleep disturbances (42%). Thirty-nine (7%) patients were seropositive for , 37 (7%) for spp., 36 (7%) for TBEV, 12 (2%) for spp., 10 (2%) for , and three (0.6%) for Typhi. None of the febrile patients tested positive for WNV antibodies. Of the patients, 73% were negative for all pathogens. Our results indicate that most of the targeted pathogens are present in Georgia, and highlight the importance of enhancing laboratory capacity for these infectious diseases.


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  • Received : 01 Jun 2015
  • Accepted : 20 Aug 2015
  • Published online : 06 Jan 2016

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