Volume 94, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



In December 2013, chikungunya virus (CHIKV) was isolated for the first time in the Western Hemisphere (WH) during an epidemic on the island of St. Martin. Subsequently, the virus has spread to 42 countries or territories in the Caribbean, Central, South, and North America. In this study, we have determined the full genomic sequences of 29 temporally and geographically diverse CHIKV strains from 16 countries of the WH. Phylogenetic analyses revealed minimal evolution among compared emergent CHIKV strains of the New World.


Article metrics loading...

The graphs shown below represent data from March 2017
Loading full text...

Full text loading...



  1. Carey DE, , 1971. Chikungunya and dengue: a case of mistaken identity. J Hist Med Allied Sci 26: 243262.[Crossref] [Google Scholar]
  2. Dickson SH, , 1839. On Dengue: Its History, Pathology and Treatment. Philadelphia, PA: Haswell, Barrington and Haswell, 523. [Google Scholar]
  3. Dickson SH, , 1859. Elements of Medicine: A Compendious View of Pathology and Therapeutics; or the History and Treatment of Diseases. Philadelphia, PA: Blanchard and Lea, 744749. [Google Scholar]
  4. Weaver SC, Lecuit M, , 2015. Chikungunya virus and the global spread of a mosquito-borne disease. N Engl J Med 372: 12311239.[Crossref] [Google Scholar]
  5. Volk SM, Chen R, Tsetsarkin KA, Adams AP, Garcia TI, Sall AA, Nasar F, Schuh AJ, Holmes EC, Higgs S, Maharaj PD, Brault AC, Weaver SC, , 2010. Genome-scale phylogenetic analyses of chikungunya virus reveal independent emergences of recent epidemics and various evolutionary rates. J Virol 84: 64976504.[Crossref] [Google Scholar]
  6. Mavalankar D, Shastri P, Raman P, , 2007. Chikungunya epidemic in India: a major public-health disaster. Lancet Infect Dis 7: 306307.[Crossref] [Google Scholar]
  7. Lanciotti RS, Kosoy OL, Laven JJ, Panella AJ, Velez JO, Lambert AJ, Campbell GL, , 2007. Chikungunya virus in US travelers returning from India, 2006. Emerg Infect Dis 13: 764767.[Crossref] [Google Scholar]
  8. Tsetsarkin KA, Vanlandingham DL, McGee CE, Higgs S, , 2007. A single mutation in chikungunya virus affects vector specificity and epidemic potential. PLoS Pathog 3: e201.[Crossref] [Google Scholar]
  9. Halstead SB, , 2015. Reappearance of chikungunya, formerly called dengue, in the Americas. Emerg Infect Dis 21: 557561.[Crossref] [Google Scholar]
  10. Lanciotti RS, Valadere AM, , 2014. Transcontinental movement of Asian genotype chikungunya virus. Emerg Infect Dis 20: 14001402.[Crossref] [Google Scholar]
  11. Sam IC, Loong SK, Michael JC, Chua CL, Wan Sulaiman WY, Vythilingam I, Chan SY, Chiam CW, Yeong YS, AbuBakar S, Chan YF, , 2012. Genotypic and phenotypic characterization of chikungunya virus of different genotypes from Malaysia. PLoS One 7: e50476.[Crossref] [Google Scholar]

Data & Media loading...

  • Received : 19 May 2015
  • Accepted : 05 Dec 2015
  • Published online : 06 Apr 2016

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error