1921
Volume 93, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

In countries with a high-burden of tuberculosis (TB), it has been well established that there is an increased incidence of TB among patients with diabetes. However, in countries with a low burden of TB there are conflicting reports. This study aimed to determine if diabetes was associated with TB in patients admitted to a teaching hospital in tropical Australia. A 20-year retrospective study found patients with comorbid diabetes were seven times overrepresented in the TB patient population when compared with the general population. This study demonstrates a strong association between TB and diabetes regardless of TB endemicity.

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/content/journals/10.4269/ajtmh.15-0264
2015-09-02
2017-11-19
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References

  1. World Health Organization, 2014. Global Tuberculosis Report 2014. Available at: http://www.who.int/tb/publications/global_report/en/. Accessed March 2015.
  2. Faurholt-Jepsen D, , 2013. The double burden. Dan Med J 60: B4673.
  3. Bridson TL, Govan BL, Norton RE, Schofield L, Ketheesan N, , 2014. The double burden: a new-age pandemic meets an ancient infection. Trans R Soc Trop Med Hyg 108: 676678.[Crossref]
  4. Hodgson K, Morris J, Bridson T, Govan B, Rush C, Ketheesan N, , 2015. Immunological mechanisms contributing to the double burden of diabetes and intracellular bacterial infections. Immunology 144: 171185.[Crossref]
  5. Kumar NP, Banurekha VV, Nair D, Sridhar R, Kornfeld H, Nutman TB, Babu S, , 2014. Coincident pre-diabetes is associated with dysregulated cytokine responses in pulmonary tuberculosis. PLoS ONE 9: e112108.[Crossref]
  6. Jeon CY, Murray MB, , 2008. Diabetes mellitus increases the risk of active tuberculosis: a systematic review of 13 observational studies. PLoS Med 5: e152.[Crossref]
  7. Viswanathan V, Kumpatla S, Aravindalochanan V, Rajan R, Chinnasamy C, Srinivasan R, Selvam JM, Kapur A, , 2012. Prevalence of diabetes and pre-diabetes and associated risk factors among tuberculosis patients in India. PLoS ONE 7: e41367.[Crossref]
  8. Leegaard A, Riis A, Kornum JB, Prahl JB, Thomsen VO, Sorensen HT, Horsburgh CR, Thomsen RW, , 2011. Diabetes, glycemic control, and risk of tuberculosis: a population-based case-control study. Diabetes Care 34: 25302535.[Crossref]
  9. Dobler CC, Flack JR, Marks GB, , 2012. Risk of tuberculosis among people with diabetes mellitus: an Australian nationwide cohort study. BMJ Open 2: e000666.[Crossref]
  10. Restrepo BI, Fisher-Hoch SP, Crespo JG, Whitney E, Perez A, Smith B, McCormick JB, , 2007. Type 2 diabetes and tuberculosis in a dynamic bi-national border population. Epidemiol Infect 135: 483491.[Crossref]
  11. International Diabetes Federation, 2011. IDF Diabetes Atlas Fifth Edition. Available at: http://www.idf.org/diabetesatlas. Accessed March 2015.
  12. Pan SC, Ku CC, Kao D, Ezzati M, Fang CT, Lin HH, , 2015. Effect of diabetes on tuberculosis control in 13 countries with high tuberculosis: a modelling study. Lancet Diabetes Endocrinol 3: 32330.[Crossref]
  13. Restrepo BI, Fisher-Hoch SP, Pino PA, Salinas A, Rahbar MH, Mora F, Cortes-Penfield N, McCormick JB, , 2008. Tuberculosis in poorly controlled type 2 diabetes: altered cytokine expression in peripheral white blood cells. Clin Infect Dis 47: 634641.[Crossref]
  14. Baker M, Harries A, Jeon C, Hart J, Kapur A, Lonnroth K, Ottmani SE, Goonesekera S, Murray M, , 2011. The impact of diabetes on tuberculosis treatment outcomes: a systematic review. BMC Med 9: 81.[Crossref]
  15. Wang CS, Yang CJ, Chen HC, Chuang SH, Chong IW, Hwang JJ, Huang MS, , 2009. Impact of type 2 diabetes on manifestations and treatment outcome of pulmonary tuberculosis. Epidemiol Infect 137: 203210.[Crossref]
  16. Viswanathan V, Vigneswari A, Selvan K, Satyavani K, Rajeswari R, Kapur A, , 2014. Effect of diabetes on treatment outcome of smear-positive pulmonary tuberculosis-a report from south India. J Diabetes Complications 28: 162165.[Crossref]
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  • Received : 07 Apr 2015
  • Accepted : 30 Apr 2015

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