1921
Volume 94, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract

This report presents two cases of visceral leishmaniasis (VL) recurrence where the microscopy of the splenic smear failed in diagnosis. However, a strong clinical suspicion compelled further evaluation by polymerase chain reaction (PCR), which validated the etiology. This short report highlights the usefulness of PCR in diagnosing cases of suspected smear-negative VL recurrence.

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2016-01-06
2017-09-23
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References

  1. Bangladesh Disease Control Unit, Directorate General Health Service, 2013. Annual Report. Bangladesh, India: Ministry of Health and Family Welfare, Government of Bangladesh.
  2. Ahmed BN, Nabi SG, Rahman M, Selim S, Bashar A, Rashid MM, Lira FY, Chowdhury TA, Mondal D, , 2014. Kala-azar (visceral leishmaniasis) elimination in Bangladesh: successes and challenges. Curr Trop Med Rep 1: 163169.[Crossref]
  3. Bourgeois N, Bastien P, Reynes J, Makinson A, Rouanet I, Lachaud L, , 2010. “Active chronic visceral leishmaniasis” in HIV-1-infected patients demonstrated by biological and clinical long-term follow-up of 10 patients. HIV Med 11: 670673.[Crossref]
  4. Bangladesh Disease Control Unit, Directorate General Health Service, 2013. National Guideline for Kala-azar Case Management. Bangladesh, India: Ministry of Health and Family Welfare, Government of Bangladesh.
  5. Srivastava P, Dayama A, Mehrotra S, Sundar S, , 2010. Diagnosis of visceral leishmaniasis. Trans R Soc Trop Med Hyg 105: 16.[Crossref]
  6. Maurya R, Singh RK, Kumar B, Salotra P, Rai M, Sundar S, , 2005. Evaluation of PCR for diagnosis of Indian kala-azar and assessment of cure. J Clin Microbiol 43: 30383041.[Crossref]
  7. Mondal D, Alvar J, Hasnain MG, Hossain MS, Ghosh D, Huda MM, Nabi SG, Sundar S, Matlashewski G, Arana B, , 2014. Efficacy and safety of single-dose liposomal amphotericin B for visceral leishmaniasis in a rural public hospital in Bangladesh: a feasibility study. Lancet Glob Health 2: e51e57.[Crossref]
  8. Soldin SJ, Brugnara C, Hicks JM, , 1999. Pediatric Reference Ranges, 3rd edition. Washington, DC: AACC Press.
  9. Hay WW, Hayward AR, Levin MJ, Sondheimer JM, , 2000. Current Pediatric Diagnosis and Treatment, 15th edition. New York, NY: Lange Medical Books/McGraw Hill.
  10. Salam MA, Mondal D, Kabir M, Haque R, , 2010. Detection of urinary leishmanial antigen by latex agglutination test (KAtex) in kala-azar patients. Bangladesh J Med Sci 9: 216222.
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  • Received : 15 Feb 2015
  • Accepted : 06 Oct 2015

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