1921
Volume 93, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

Cache Valley virus (CVV; Family , Genus ) is a mosquito-borne zoonosis that frequently infects humans and livestock in North and Central America. In the northeastern United States, CVV transmission is unpredictable from year-to-year and may derive from the periodic extinction and reintroduction of new virus strains into this region. To evaluate this possibility, we sequenced and analyzed numerous CVV isolates sampled in Connecticut during an 18-year period to determine how the virus population may change over time. Phylogenetic analyses showed the establishment of a new viral lineage during 2010 that became dominant by 2014 and appears to have originated from southern Mexico. CVV strains from Connecticut also grouped into numerous sub-clades within each lineage that included viruses from other U.S. states and Canada. We did not observe the development and stable persistence of local viral clades in Connecticut, which may reflect the episodic pattern of CVV transmission. Together, our data support the emergence of a new lineage of CVV in the northeastern United States and suggest extensive dispersal of viral strains in North America.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.15-0132
2015-07-08
2017-11-20
Loading full text...

Full text loading...

/deliver/fulltext/14761645/93/1/11.html?itemId=/content/journals/10.4269/ajtmh.15-0132&mimeType=html&fmt=ahah

References

  1. Calisher CH, Francy DB, Smith GC, Muth DJ, Lazuick JS, Karabatsos N, Jakob WL, McLean RG, , 1986. Distribution of Bunyamwera serogroup viruses in North America, 1956–1984. Am J Trop Med Hyg 35: 429443.
  2. Grimstad PR, Service MW, , 2001. Cache Valley virus. , ed. Encyclopedia of Arthropod-Transmitted Infections of Man and Domestic Animals. New York: CABI Publishing, 101104.
  3. Blackmore CG, Grimstad PR, , 1998. Cache Valley and Potosi viruses (Bunyaviridae) in white-tailed deer (Odocoileus virginianus): experimental infections and antibody prevalence in natural populations. Am J Trop Med Hyg 59: 704709.
  4. Neitzel DF, Grimstad PR, , 1991. Serological evidence of California group and Cache Valley virus infection in Minnesota white-tailed deer. J Wildl Dis 27: 230237.[Crossref]
  5. Kokernot RH, Hayes J, Tempelis CH, Chan DH, Boyd KR, Anderson RJ, , 1969. Arbovirus studies in the Ohio-Mississippi Basin, 1964–1967. IV. Cache Valley virus. Am J Trop Med Hyg 18: 768773.
  6. Buescher EL, Byrne RJ, Clarke GC, Gould DJ, Russell PK, Scheider FG, Yuill TM, , 1970. Cache Valley virus in the Del Mar Va Peninsula. I. Virologic and serologic evidence of infection. Am J Trop Med Hyg 19: 493502.
  7. Blitvich BJ, Saiyasombat R, Talavera-Aguilar LG, Garcia-Rejon JE, Farfan-Ale JA, Machain-Williams C, Lorono-Pino MA, , 2012. Orthobunyavirus antibodies in humans, Yucatan Peninsula, Mexico. Emerg Infect Dis 18: 16291632.[Crossref]
  8. Sexton DJ, Rollin PE, Breitschwerdt EB, Corey GR, Myers SA, Dumais MR, Bowen MD, Goldsmith CS, Zaki SR, Nichol ST, Peters CJ, Ksiazek TG, , 1997. Life-threatening Cache Valley virus infection. N Engl J Med 336: 547549.[Crossref]
  9. Campbell GL, Mataczynski JD, Reisdorf ES, Powell JW, Martin DA, Lambert AJ, Haupt TE, Davis JP, Lanciotti RS, , 2006. Second human case of Cache Valley virus disease. Emerg Infect Dis 12: 854856.[Crossref]
  10. Nguyen NL, Zhao G, Hull R, Shelly MA, Wong SJ, Wu G, St George K, Wang D, Menegus MA, , 2013. Cache valley virus in a patient diagnosed with aseptic meningitis. J Clin Microbiol 51: 19661969.[Crossref]
  11. Edwards JF, Livingston CW, Chung SI, Collisson EC, , 1989. Ovine arthrogryposis and central nervous system malformations associated with in utero Cache Valley virus infection: spontaneous disease. Vet Pathol 26: 3339.[Crossref]
  12. Chung SI, Livingston CW, Jr Edwards JF, Crandell RW, Shope RE, Shelton MJ, Collisson EW, , 1990. Evidence that Cache Valley virus induces congenital malformations in sheep. Vet Microbiol 21: 297307.[Crossref]
  13. Chung SI, Livingston CW, Jr Edwards JF, Gauer BB, Collisson EW, , 1990. Congenital malformations in sheep resulting from in utero inoculation of Cache Valley virus. Am J Vet Res 51: 16451648.
  14. Hunt AR, Calisher CH, , 1979. Relationships of bunyamwera group viruses by neutralization. Am J Trop Med Hyg 28: 740749.
  15. Calisher CH, Sabattini MS, Monath TP, Wolff KL, , 1988. Cross-neutralization tests among Cache Valley virus isolates revealing the existence of multiple subtypes. Am J Trop Med Hyg 39: 202205.
  16. Lambert AJ, Lanciotti RS, , 2008. Molecular characterization of medically important viruses of the genus Orthobunyavirus. J Gen Virol 89: 25802585.[Crossref]
  17. Blitvich BJ, Saiyasombat R, Dorman KS, Garcia-Rejon JE, Farfan-Ale JA, Lorono-Pino MA, , 2012. Sequence and phylogenetic data indicate that an orthobunyavirus recently detected in the Yucatan Peninsula of Mexico is a novel reassortant of Potosi and Cache Valley viruses. Arch Virol 157: 11991204.[Crossref]
  18. Blitvich BJ, Lorono-Pino MA, Garcia-Rejon JE, Farfan-Ale JA, Dorman KS, , 2012. Nucleotide sequencing and serologic analysis of Cache Valley virus isolates from the Yucatan Peninsula of Mexico. Virus Genes 45: 176180.[Crossref]
  19. Pabbaraju K, Ho KC, Wong S, Fox JD, Kaplen B, Tyler S, Drebot M, Tilley PA, , 2009. Surveillance of mosquito-borne viruses in Alberta using reverse transcription polymerase chain reaction with generic primers. J Med Entomol 46: 640648.[Crossref]
  20. Andreadis TG, Armstrong PM, Anderson JF, Main AJ, , 2014. Spatial-temporal analysis of Cache Valley virus (Bunyaviridae: Orthobunyavirus) infection in anopheline and culicine mosquitoes (Diptera: Culicidae) in the northeastern United States, 1997–2012. Vector Borne Zoonotic Dis 14: 763773.[Crossref]
  21. Anderson JF, Main AJ, Armstrong PM, Andreadis TG, Ferrandino FJ, , 2015. Arboviruses in North Dakota, 2003–2006. Am J Trop Med Hyg 92: 377393.[Crossref]
  22. Main AJ, , 1981. Arbovirus surveillance in Connecticut IV. Bunyamwera group. Mosq News 41: 490494.
  23. Calisher CH, Gutierrez E, Francy DB, Alava A, Muth DJ, Lazuick JS, , 1983. Identification of hitherto unrecognized arboviruses from Ecuador: members of serogroups B, C, Bunyamwera, Patois, and Minatitlan. Am J Trop Med Hyg 32: 877885.
  24. Tamura K, Stecher G, Peterson D, Filipski A, Kumar S, , 2013. MEGA6: Molecular Evolutionary Genetics Analysis version 6.0. Mol Biol Evol 30: 27252729.[Crossref]
  25. Briese T, Kapoor V, Lipkin WI, , 2007. Natural M-segment reassortment in Potosi and Main Drain viruses: implications for the evolution of orthobunyaviruses. Arch Virol 152: 22372247.[Crossref]
  26. Rico-Hesse R, Harrison LM, Salas RA, Tovar D, Nisalak A, Ramos C, Boshell J, de Mesa MT, Nogueira RM, da Rosa AT, , 1997. Origins of dengue type 2 viruses associated with increased pathogenicity in the Americas. Virology 230: 244251.[Crossref]
  27. Messer WB, Gubler DJ, Harris E, Sivananthan K, de Silva AM, , 2003. Emergence and global spread of a dengue serotype 3, subtype III virus. Emerg Infect Dis 9: 800809.[Crossref]
  28. OhAinle M, Balmaseda A, Macalalad AR, Tellez Y, Zody MC, Saborio S, Nunez A, Lennon NJ, Birren BW, Gordon A, Henn MR, Harris E, , 2011. Dynamics of dengue disease severity determined by the interplay between viral genetics and serotype-specific immunity. Sci Transl Med 3: 114ra128.[Crossref]
  29. Ebel GD, Carricaburu J, Young D, Bernard KA, Kramer LD, , 2004. Genetic and phenotypic variation of West Nile virus in New York, 2000–2003. Am J Trop Med Hyg 71: 493500.
  30. Davis CT, Ebel GD, Lanciotti RS, Brault AC, Guzman H, Siirin M, Lambert A, Parsons RE, Beasley DW, Novak RJ, Elizondo-Quiroga D, Green EN, Young DS, Stark LM, Drebot MA, Artsob H, Tesh RB, Kramer LD, Barrett AD, , 2005. Phylogenetic analysis of North American West Nile virus isolates, 2001–2004: evidence for the emergence of a dominant genotype. Virology 342: 252265.[Crossref]
  31. Cologna R, Armstrong PM, Rico-Hesse R, , 2005. Selection for virulent dengue viruses occurs in humans and mosquitoes. J Virol 79: 853859.[Crossref]
  32. Lambrechts L, Fansiri T, Pongsiri A, Thaisomboonsuk B, Klungthong C, Richardson JH, Ponlawat A, Jarman RG, Scott TW, , 2012. Dengue-1 virus clade replacement in Thailand associated with enhanced mosquito transmission. J Virol 86: 18531861.[Crossref]
  33. Wittke V, Robb TE, Thu HM, Nisalak A, Nimmannitya S, Kalayanrooj S, Vaughn DW, Endy TP, Holmes EC, Aaskov JG, , 2002. Extinction and rapid emergence of strains of dengue 3 virus during an interepidemic period. Virology 301: 148156.[Crossref]
  34. Armstrong PM, Rico-Hesse R, , 2003. Efficiency of dengue serotype 2 virus strains to infect and disseminate in Aedes aegypti . Am J Trop Med Hyg 68: 539544.
  35. Armstrong PM, Andreadis TG, , 2007. Genetic relationships of Jamestown Canyon virus strains infecting mosquitoes collected in Connecticut. Am J Trop Med Hyg 77: 11571162.
  36. Andreadis TG, Anderson JF, Armstrong PM, Main AJ, , 2008. Isolations of Jamestown Canyon virus (Bunyaviridae: Orthobunyavirus) from field-collected mosquitoes (Diptera: Culicidae) in Connecticut, USA: a ten-year analysis, 1997–2006. Vector Borne Zoonotic Dis 8: 175188.[Crossref]
  37. Berry RL, Lalondie-Weigert BJ, Calisher CH, Parsons MA, Bear GT, , 1977. Evidence for transovarial transmission of Jamestown Canyon virus in Ohio. Mosq News 37: 494496.
  38. Boromisa RD, Grimstad PR, , 1986. Virus-vector-host relationships of Aedes stimulans and Jamestown Canyon virus in a northern Indiana enzootic focus. Am J Trop Med Hyg 35: 12851295.
  39. Armstrong PM, Andreadis TG, , 2006. A new genetic variant of La Crosse virus (Bunyaviridae) isolated from New England. Am J Trop Med Hyg 75: 491496.
http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.15-0132
Loading
/content/journals/10.4269/ajtmh.15-0132
Loading

Data & Media loading...

  • Received : 13 Dec 2015
  • Accepted : 28 Mar 2015

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error