1921
Volume 93, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract

A total of 1,136 samples from 289 households in four provinces in northern Laos were subjected to Japanese encephalitis virus (JEV) and dengue virus hemagglutination inhibition (DENV HI). Overall, antibodies to JEV were detected by HI in 620 (54.6%) of 1,136 people; of which 217 (19.1%) had HI activity against JEV only. Antibodies to DENV4 were detected by HI in 526 (46.3%) of 1,136 people; of which 124 (10.9%) had HI activity against DENV4 only. Antibodies to DENV1–3 were detected by HI in 296 (26.1%), 274 (24.1%), and 283 (24.9) of 1,136 people, respectively; of which 7, 1, and 0, respectively, had HI activity against DENV1–3 only. JEV was the most prevalent in Oudomxay, Luangprabang, and Huaphan provinces and DENV4 was the most prevalent in Xiengkhouang province. Seroprevalence for JEV increased with increasing age and wealth and was higher in villages where rice was cultivated in paddy fields and highest for people of Lao-Tai ethnicity.

[open-access] This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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2017-11-21
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References

  1. Tarantola A, Goutard F, Newton P, de Lamballerie X, Lortholary O, Cappelle J, Buchy P, , 2014. Estimating the burden of Japanese encephalitis virus and other encephalitides in countries of the Mekong region. PLoS Negl Trop Dis 8: e2533.[Crossref]
  2. Dash AP, Bhatia R, Sunyoto T, Mourya DT, , 2013. Emerging and re-emerging arboviral diseases in southeast Asia. J Vector Borne Dis 50: 7784.
  3. Mayxay M, Castonguay-Vanier J, Chansamouth V, Dubot-Pérès A, Paris DH, Phetsouvanh R, Tangkhabuanbutra J, Douangdala P, Inthalath S, Souvannasing P, Slesak G, Tongyoo N, Chanthongthip A, Panyanouvong P, Sibounheuang B, Phommasone K, Dohnt M, Phonekeo D, Hongvanthong B, Xayadeth S, Ketmayoon P, Blacksell SD, Moore CE, Craig SB, Burns MA, von Sonnenburg F, Corwin A, de Lamballerie X, González IJ, Christophel EM, Cawthorne A, Bell D, Newton PN, , 2013. Causes of non-malarial fever in Laos: a prospective study. Lancet Glob Health 1: e46e54.[Crossref]
  4. Khampapongpane B, Lewis HC, Ketmayoon P, Phonekeo D, Somoulay V, Khamsing A, Phengxay M, Sisouk T, Vongphrachanh P, Bryant JE, , 2014. National dengue surveillance in the Lao People's Democratic Republic, 2006–2012: epidemiological and laboratory findings. Western Pac Surveill Response 5: 713.[Crossref]
  5. Hiscox A, Khammanithong P, Kaul S, Sananikhom P, Luthi R, Hill N, Brey PT, Lindsay SW, , 2013. Risk factors for mosquito house entry in the Lao PDR. PLoS One 8: e62769.[Crossref]
  6. Conlan JV, Vongxay K, Jarman RG, Gibbons RV, Lunt RA, Fenwick S, Thompson RC, Blacksell SD, , 2012. Serologic study of pig-associated viral zoonoses in Laos. Am J Trop Med Hyg 86: 10771084.[Crossref]
  7. Erlanger TE, Weiss S, Keiser J, Utzinger J, Wiedenmayer K, , 2009. Past, present, and future of Japanese encephalitis. Emerg Infect Dis 15: 17.[Crossref]
  8. Campbell GL, Hills SL, Fischer M, Jacobson JA, Hoke CH, Hombach JM, Marfin AA, Solomon T, Tsai TF, Tsu VD, Ginsburg AS, , 2011. Estimated global incidence of Japanese encephalitis: a systematic review. Bull World Health Organ 89: 766774.[Crossref]
  9. Conlan JV, Vongxay K, Khamlome B, Dorny P, Sripa B, Elliot A, Blacksell SD, Fenwick S, Thompson RC, , 2012. A cross-sectional study of Taenia solium in a multiple Taeniid-endemic region reveals competition may be protective. Am J Trop Med Hyg 87: 281291.[Crossref]
  10. Conlan JV, Khamlome B, Vongxay K, Elliot A, Pallant L, Sripa B, Blacksell SD, Fenwick S, Thompson RC, , 2012. Soil-transmitted helminthiasis in Laos: a community-wide cross-sectional study of humans and dogs in a mass drug administration environment. Am J Trop Med Hyg 86: 624634.[Crossref]
  11. Clarke DH, Casals J, , 1955. Improved methods for hemagglutination studies with arthropod-borne viruses. Proc Soc Exp Biol Med 8: 9699.[Crossref]
  12. Hiscox A, Winter CH, Vongphrachanh P, Sisouk T, Somoulay V, Phompida S, Kaul S, Sananikhom P, Nguyen TY, Paul RE, Brey P, Bryant JE, , 2010. Serological investigations of Flavivirus prevalence in Khammouane Province, Lao People's Democratic Republic, 2007–2008. Am J Trop Med Hyg 83: 11661169.[Crossref]
  13. Conlan JV, Vongxay K, Khamlome B, Gomez-Morales MA, Pozio E, Blacksell SD, Fenwick S, Thompson RC, , 2014. Patterns and risks of trichinella infection in humans and pigs in northern Laos. PLoS Negl Trop Dis 8: e3034.[Crossref]
  14. van den Hurk AF, Ritchie SA, Mackenzie JS, , 2009. Ecology and geographical expansion of Japanese encephalitis virus. Annu Rev Entomol 54: 1735.[Crossref]
  15. Vallée J, Dubot-Pérès A, Ounaphom P, Sayavong C, Bryant JE, Gonzalez JP, , 2009. Spatial distribution and risk factors of dengue and Japanese encephalitis virus infection in urban settings: the case of Vientiane, Lao PDR. Trop Med Int Health 14: 11341142.[Crossref]
  16. van-den-Hurk AF, Ritchie SA, Johansen CA, Mackenzie JS, Smith GA, , 2008. Domestic pigs and Japanese encephalitis virus infection, Australia. Emerg Infect Dis 14: 17361738.[Crossref]
  17. Liu W, Gibbons RV, Kari K, Clemens JD, Nisalak A, Marks F, Xu ZY, , 2010. Risk factors for Japanese encephalitis: a case-control study. Epidemiol Infect 138: 12921297.[Crossref]
  18. Chin R, Torresi J, , 2013. Japanese B encephalitis: an overview of the disease and use of Chimerivax-JE as a preventative vaccine. Infect Dis Ther 2: 145158.[Crossref]
  19. World Health Organization. The Lao People's Democratic Republic Conducts A Successful Multi-antigen Vaccination Campaign and Introduces Japanese Encephalitis Vaccine in its Northern Provinces. Available at: http://www.wpro.who.int/immunization/news/lao_multi-antigen_vax_campaign_and_intro_JE_vax/en/. Accessed December 11, 2014.
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Supplementary Data

Supplementary Table

  • Received : 26 Jan 2015
  • Accepted : 23 Jun 2015

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