1921
Volume 93, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

In recent years, the number of humans infected with has risen rapidly. Diagnosis is based mainly on detection of eggs in stool analysis. The rate of infection in Egypt is unknown. In this retrospective study, we describe 23 cases of hepatic fascioliasis, and only 2 of these cases showed eggs in stools. The symptoms of infection, such as pyrexia of unknown origin, epigastric pain, and abdominal distension, were suggestive. Imaging techniques, including abdominal ultrasonography and computed tomography, were very helpful in detecting hepatic changes. An indirect hemagglutination assay proved to be of value for diagnosis. Treatment using a 2-day triclabendazole regimen cured the infection and signs of hepatic involvement disappeared. Combining both imaging techniques and laboratory tests is essential for diagnosis of fascioliasis in the early stage.

Loading

Article metrics loading...

The graphs shown below represent data from March 2017
/content/journals/10.4269/ajtmh.15-0030
2015-07-08
2019-11-19
Loading full text...

Full text loading...

/deliver/fulltext/14761645/93/1/76.html?itemId=/content/journals/10.4269/ajtmh.15-0030&mimeType=html&fmt=ahah

References

  1. Mas-Coma S, Valero MA, Bargues MD, , 2009. Chapter 2. Fasciola, lymnaeids and human fascioliasis, with a global overview on disease transmission, epidemiology, evolutionary genetics, molecular epidemiology and control. Adv Parasitol 69: 41146.[Crossref] [Google Scholar]
  2. Periago MV, Valero MA, El Sayed M, Ashrafi K, El Wakeel A, Mohamed MY, Desquesnes M, Curtale F, Mas-Coma S, , 2008. First phenotypic description of Fasciola hepatica/Fasciola gigantica intermediate forms from the human endemic area of the Nile Delta, Egypt. Infect Genet Evol 8: 5158.[Crossref] [Google Scholar]
  3. Lotfy WM, El-Morshedy HN, Abou El-Hoda M, El-Tawila MM, Omar EA, Farag HF, , 2002. Identification of the Egyptian species of Fasciola . Vet Parasitol 103: 323332.[Crossref] [Google Scholar]
  4. Valero MA, Perez-Crespo I, Periago MV, Khoubbane M, Mas-Coma S, , 2009. Fluke egg characteristics for the diagnosis of human and animal fascioliasis by Fasciola hepatica and F. gigantica . Acta Trop 111: 150159.[Crossref] [Google Scholar]
  5. Soliman MF, , 2008. Epidemiological review of human and animal fascioliasis in Egypt. J Infect Dev Ctries 2: 182189.[Crossref] [Google Scholar]
  6. Marcos LA, Terashima A, Gotuzzo E, , 2008. Update on hepatobiliary flukes: fascioliasis, opisthorchiasis and clonorchiasis. Curr Opin Infect Dis 21: 523530.[Crossref] [Google Scholar]
  7. Zali MR, Ghaziani T, Shahraz S, Hekmatdoost A, Radmehr A, , 2004. Liver, spleen, pancreas and kidney involvement by human fascioliasis: imaging findings. BMC Gastroenterol 4: 15.[Crossref] [Google Scholar]
  8. Vatsal DK, Kapoor S, Venkatesh V, Vatsal P, Husain N, , 2006. Ectopic fascioliasis in the dorsal spine: case report. Neurosurgery 59: E706E707; discussion E706–E707.[Crossref] [Google Scholar]
  9. Lim JH, Mairiang E, Ahn GH, , 2008. Biliary parasitic diseases including clonorchiasis, opisthorchiasis and fascioliasis. Abdom Imaging 33: 157165.[Crossref] [Google Scholar]
  10. Fang W, Chen F, Liu H-K, Yang Q, Yang L, , 2014. Comparison between albendazole and triclabendazole against Fasciola gigantica in human. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 26: 106108. [Google Scholar]
  11. Abdel-Hafeez EH, Ahmad AK, Ali BA, Moslam FA, , 2012. Opportunistic parasites among immunosuppressed children in Minia District, Egypt. Korean J Parasitol 50: 5762.[Crossref] [Google Scholar]
  12. Abdel-Aziz NM, , 1993. Incidence and Public Health Importance of Fascioliasis in Slaughtered Animals in Assiut Province, M.Sc. Thesis, Faculty of Veterinary Medicine, Assiut University, Egypt. [Google Scholar]
  13. Arafa MI, Fouad IA, , 2008. Studies on some internal parasites of goats in assiut governorate especially which affecting liver. Assiut Univ Bull Environ Res 11: 5773. [Google Scholar]
  14. Mas-Coma MS, Esteban JG, Bargues MD, , 1999. Epidemiology of human fascioliasis: a review and proposed new classification. Bull World Health Organ 77: 340346. [Google Scholar]
  15. Esteban JG, Gonzalez C, Curtale F, Muñoz-Antoli C, Valero MA, Bargues MD, El Sayed M, El Wakeel AAEW, Abdel-Wahab Y, Montresor A, Engels D, Savioli L, Mas-Coma S, , 2003. Hyperendemic fascioliasis associated with schistosomiasis in villages in the Nile Delta of Egypt. Am J Trop Med Hyg 69: 429437. [Google Scholar]
  16. Youssef AI, Uga S, , 2014. Review of parasitic zoonoses in Egypt. Trop Med Health 42: 314.[Crossref] [Google Scholar]
  17. El-Khoby T, Galal N, Fenwick A, Barakat R, El-Hawey A, Nooman Z, Habib M, Abdel-Wahab F, Gabr NS, Hammam HM, Hussein MH, Mikhail NNH, Cline BL, Strickland GT, , 2000. The epidemiology of schistosomiasis in Egypt: summary findings in nine governorates. Am J Trop Med Hyg 62: 8899. [Google Scholar]
  18. Barakat RMR, , 2013. Epidemiology of schistosomiasis in Egypt: travel through time review. J Adv Res 4: 425432.[Crossref] [Google Scholar]
  19. Trent SC, , 1963. Reevaluation of World War II veterans with filariasis acquired in the South Pacific. Am J Trop Med Hyg 12: 877887. [Google Scholar]
  20. Marcos LA, Tagle M, Terashima A, Bussalleu A, Ramirez C, Carrasco C, Valdez L, Huerta-Mercado J, Freedman DO, Vinetz JM, Gotuzzo E, , 2008. Natural history, clinicoradiologic correlates, and response to triclabendazole in acute massive fascioliasis. Am J Trop Med Hyg 78: 222227. [Google Scholar]
http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.15-0030
Loading
/content/journals/10.4269/ajtmh.15-0030
Loading

Data & Media loading...

  • Received : 14 Jan 2015
  • Accepted : 11 Mar 2015
  • Published online : 08 Jul 2015

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error