1921
Volume 93, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

The mite has significant prevalence worldwide. Blo t 5 is a major allergen that has been associated with sensitization and allergic symptoms in many asthmatic patients. Besides house dust, contaminated foodstuffs are an important source of exposure to allergens. In this study, a double sandwich enzyme-linked immunosorbent assay (ELISA) using mAb 4D4 and biotinylated mAb 4G9 was done to detect Blo t 5 allergen in different types of raw and processed foods, including wheat, corn, rice, bean, wheat and corn flour, cake, and rusk, which were collected from retail stores in the Nile Delta of Egypt. Out of 88 samples, 38 (43.2%) were positive for Blo t 5 allergen with no significant statistical difference in positivity according to food type. In positive samples, the Blo t 5 concentration ranged from 10 ng/g to 790 ng/g. This study showed that Blo t 5 should be considered as an important allergen that presents a risk to the Egyptian population and should become a routine allergen in the skin prick test to improve the management of allergic disease.

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2015-07-08
2017-11-25
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References

  1. WHO, 2003. Prevention of Allergy and Allergic Asthma. WHO meeting report. WHO/MNC/CRA/03.2. Geneva, Switzerland: World Health Organization.
  2. Bousquet J, Dahl R, Khaltaev N, , 2007. Global alliance against chronic respiratory diseases. Allergy 62: 216223.[Crossref]
  3. Platts-Mills TA, Solomon WR, Middleton E, Jr Reed CE, Ellis EF, Adkinson NF, Jr Yunginger JW, Busse WW, , 1993. Aerobiology and inhalant allergens. , eds. Allergy: Principles and Practice, 4th edition. St Louis, MO: Mosby-Year Book, 469528.
  4. Cromwell O, Kay AB, Kaplan AP, Bousquet J, Holt PG, , 1997. Biochemistry of allergens. , eds. Allergy and Allergic Diseases, Volume 1, 2nd edition. Oxford, United Kingdom: Blackwell Science Ltd., 797810.
  5. Arlian LG, Platts-Mills TA, , 2001. The biology of dust mites and the remediation of mite allergens in allergic disease. J Allergy Clin Immunol 107: S406S413.[Crossref]
  6. Sanchez-Borges M, Capriles-Hulett A, Fernandez-Caldas E, Suarez-Chacon R, Caballero F, Castillo S, Sotillo E, , 1997. Mite-contaminated foods as a cause of anaphylaxis. J Allergy Clin Immunol 99: 738743.[Crossref]
  7. Sanchez-Borges M, Suárez-Chacon R, Capriles-Hulett A, Caballero-Fonseca F, Iraola V, Fernandez-Caldas E, , 2009. Pancake syndrome (oral mite anaphylaxis). World Allergy Organ J 2: 9196.[Crossref]
  8. Caraballo L, Puerta L, Martinez B, Moreno L, , 1994. Identification of allergens from the mite Blomia tropicalis . Clin Exp Allergy 24: 10501060.[Crossref]
  9. Juliá-Serdá G, Cabrera-Navarro P, Acosta-Fernández O, Martín-Pérez P, García-Bello MA, Antó-Boqué J, , 2012. Prevalence of sensitization to Blomia tropicalis among young adults in a temperate climate. J Asthma 49: 349354.[Crossref]
  10. Arruda LK, Chapman MD, , 1992. A review of recent immunochemical studies of Blomia tropicalis and Euroglyphus maynei allergens. Exp Appl Acarol 16: 129140.[Crossref]
  11. Barrera OM, Murgas I, Miranda RJ, , 2012. First report of anaphylactic shock caused by the ingestion of mite-infested flour in Panama. World Allergy Organ J 5 (Suppl 2): S104.
  12. Wen DC, Shyur SD, Ho CM, Chiang YC, Huang LH, Lin MT, Yang HC, Liang PH, , 2005. Systemic anaphylaxis after the ingestion of pancake contaminated with the storage mite Blomia freemani . Ann Allergy Asthma Immunol 95: 612614.[Crossref]
  13. Armentia A, Fernandez A, Perez-Santos C, De la Fuente R, Sanchez P, Méndez J, Stolle R, , 1994. Occupational allergy to mites in salty ham, chorizo and cheese. Allergol Immunopathol (Madr) 22: 152154.
  14. Franzolin MR, Baggio D, , 2000. Mite contamination in polished rice and beans commercialized in municipal markets. Rev Saude Publica 34: 7783.[Crossref]
  15. Arruda LK, Fernandez-Caldas E, Naspitz CK, Montealegre F, Chapman MD, , 1994. Molecular cloning of Blomia tropicalis allergen Blo t 5 and its sequence homology to D. pteronyssinus Der p 5. J Allergy Clin Immunol 93: 205.
  16. Arruda LK, Vailes LD, Platts-Mills TAE, Fernandez-Caldas E, Montealegre F, Lin KL, Chua KY, Rizzo MC, Naspitz CK, Chapman MD, , 1997. Sensitization to Blomia tropicalis in patients with asthma and identification of Blo t 5. Am J Respir Crit Care Med 155: 343350.[Crossref]
  17. Carvalho KA, de Melo-Neto OP, Magalhães FB, Ponte JCM, Felipe F, Santos M, Lima G, Cruz A, Pinheiro CS, Pontes-de-Carvalho L, Alcantara-Neves NM, , 2013. Blomia tropicalis Blo t 5 and Blo t 21 recombinant allergens might confer higher specificity to serodiagnostic assays than whole mite extract. BMC Immunol 14: 11.[Crossref]
  18. Caplin J, Capriles-Hulett A, Iraola V, Pinto H, Sánchez-Borges M, de los Santos G, Fernández-Caldas E, , 2009. Allergic sensitization to domestic mites in Corpus Christi, Texas. Allergy Asthma Proc 30: 166170.[Crossref]
  19. Pefura-Yone E, Kengne A, Afane-Ze E, Kuaban C, , 2014. Sensitisation to Blattella germanica among adults with asthma in Yaounde, Cameroon: a cross-sectional study. World Allergy Organ J 7: 22.[Crossref]
  20. Sun B, Zheng P, Wei N, Huang H, Zeng G, , 2014. Co-sensitization to silkworm moth (Bombyx mori) and 9 inhalant allergens among allergic patients in Guangzhou, southern China. PLoS ONE 9: e94776.[Crossref]
  21. Gamal-Eddin FM, Shoker NI, , 1989. The present status and ecology of house dust mites in El-Minia Governorate (Upper Egypt), as basis for future studies on environment pollution with house dust mite allergens or on vaccination with specific mite antigens. J Egypt Soc Parasitol 19: 332341.
  22. Kenawy MA, Awad AA, El-Shafei AM, Helmi N, Abdel-Hamid YM, El-Zohery YZA, , 2012. House dust mites associated with the asthmatic patients in some houses of Cairo, A.R. Egypt. Egypt Acad J biolog Sci 4: 15.
  23. Mollet JA, Vailes LD, Avner DB, Perzanowski MS, Arruda LA, Chapman MD, Platts-Mills TAE, , 1997. Evaluation of German cockroach (Orthoptera: Blattellidae) allergen and seasonal variation in low-income housing. J Med Entomol 34: 307311.[Crossref]
  24. Chapman MD, Smith AM, Slunt JB, Vailes LD, Arruda LK, , 1995. Immunochemical and molecular methods for defining and measuring indoor allergens: in dust and air. Pediatr Allergy Immunol 6: 812.[Crossref]
  25. DeBoer DJ, Schreiner TA, , 2001. Commercial dry dog food in the north central United States is not contaminated by Dermatophagoides house dust mites. Vet Dermatol 12: 183187.[Crossref]
  26. Yi FC, Chen JY, Chee KK, Chua KY, Lee BW, , 2009. Dust mite infestation of flour samples. Allergy 64: 17881789.[Crossref]
  27. Guerra Bernd LA, Arruda LK, Barros Antunes HB, , 2001. Oral anaphylaxis to mites. Allergy 56: 8384.[Crossref]
  28. Liccardi G, D'Amato M, D'Amato G, , 1996. Oral allergy syndrome after ingestion of salami in a subject with monosensitization to mite allergens. J Allergy Clin Immunol 98: 850852.[Crossref]
  29. Kasti GL, Codina R, Ledford DR, Lockey RF, , 1998. Mite contamination of food stuffs. J Allergy Clin Immunol 101: 2425.[Crossref]
  30. Zhang L, Chew FT, Soh SY, Yi FC, Law SY, Goh DYT, Lee BW, , 1997. Prevalence and distribution of indoor allergens in Singapore. Clin Exp Allergy 27: 876885.[Crossref]
  31. Fernandez-Caldas E, Fox RW, Bucholtz GA, Trudeau WL, Ledford DK, Lockey RF, , 1990. House dust mite allergy in Florida. Mite survey in households of mite-sensitive individuals in Tampa, Florida. Allergy Proc 11: 263267.[Crossref]
  32. Podder S, Gupta S, Saha G, , 2010. Incrimination of Blomia tropicalis as a potent allergen in house dust and its role in allergic asthma in Kolkata metropolis, India. World Allergy Organ J 3: 182187.[Crossref]
  33. Yong SB, Wu CC, Tzeng YC, Hung WC, Yang KD, , 2013. Different profiles of allergen sensitization in different ages and geographic areas in Changhua, Taiwan. J Microbiol Immunol Infect 46: 295301.[Crossref]
  34. Larenas-Linnemann D, Michels A, Dinger H, Shah-Hosseini K, Mösges R, Arias-Cruz A, Ambriz-Moreno M, Barajas MB, Javier RC, Prado M, Moreno M, Almaráz RG, García-Cobas CY, Imperial D, Muñoz RG, Hernández-Colín D, Linares-Zapien F, Luna-Pech JA, Matta-Campos JJ, Jiménez NM, Medina-Ávalos M, Hernández AM, Maldonado AM, López DN, Nazara LJ, Sanchez ER, Ramos-López JD, Rodríguez-Pérez N, Rodríguez-Ortizet PG, , 2014. Allergen sensitization linked to climate and age, not to intermittent-persistent rhinitis in a cross-sectional cohort study in the (sub) tropics. Clin Transl Allergy 4: 20.[Crossref]
  35. Sun B, Zheng P, Zhang X, Huang H, Chen D, Zeng G, , 2014. Prevalence of allergen sensitization among patients with allergic diseases in Guangzhou, southern China: a four-year observational study. Multidiscip Respir Med 9: 2.[Crossref]
  36. Oliveira-Santos J, Motta-Francob I, Barreto D, Solé R, , 2014. Asthma in adolescents—prevalence trends and associated factors in northeast Brazil. Allergol Immunopathol (Madr). doi:10.1016/j.aller.2014.05.006.
  37. Lâm HT, Ekerljung L, Bjerg A, VãnTýòng N, Lundbäck B, Rönmark E, , 2014. Sensitization to airborne allergens among adults and its impact on allergic symptoms: a population survey in northern Vietnam. Clin Transl Allergy 4: 6.[Crossref]
  38. Taketomi EA, Almeida KC, Pereira FL, Silva D, , 2010. Allergens: sources, exposure and sensitization levels, diagnostic tools and immunotherapeutical applications. JMMS 1 (12 Special Issue): 580588.
  39. Olsen AR, , 1998. Regulatory action criteria for filth and other extraneous materials II. Allergenic mites: an emerging food safety issue. Regul Toxicol Pharmacol 28: 190198.[Crossref]
  40. Erben AM, Rodriguez JL, McCullough JM, Ownby DR, , 1993. Anaphylaxis after ingestion of beignets contaminated with Dermatophagoides farinae . J Allergy Clin Immunol 92: 846849.[Crossref]
  41. Matsumoto T, Hisano T, Hamaguchi M, Miike T, , 1996. Systemic anaphylaxis after eating storage-mite-contaminated food. Int Arch Allergy Immunol 109: 197200.[Crossref]
  42. Blanco C, Quiralte J, Castillo R, Delgado J, Arteaga C, Barber D, Carrillo T, , 1997. Anaphylaxis after ingestion of wheat flour contaminated with mites. J Allergy Clin Immunol 99: 308313.[Crossref]
  43. Platts-Mills TAE, Thomas WR, Aalberse RC, Vervloet D, Chapman MD, , 1992. Dust mite allergens and asthma: report of a Second International Workshop. J Allergy Clin Immunol 89: 10461060.[Crossref]
  44. Arshad SH, , 2010. Does exposure to indoor allergens contribute to the development of asthma and allergy? Curr Allergy Asthma Rep 10: 4955.[Crossref]
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  • Received : 26 Dec 2014
  • Accepted : 11 Mar 2015

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