1921
Volume 93, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

parasites isolated, between 1979 and 1988 by the late Bryce Walton, from Dominican Republic (DR) patients with diffuse cutaneous leishmaniasis, were characterized using a panel of 12 isoenzymes, 23 monoclonal antibodies, small subunit ribosomal DNA (SSu rDNA), and multilocus sequence analysis (MLSA). The isoenzyme and monoclonal antibody profiles and the MLSA results showed that the Dominican Republic parasites were distinct from other described species. This new species belongs to the complex, which is distributed in central and parts of northern South America. It is suggested that the parasites uniqueness from other members of the complex is related to it being isolated on an island for millions of years. If () fails to adapt to some imported mammal, such as the house rat, it will be the only to be classified as an endangered species. The excessive destruction of habitats on Hispaniola threatens the survival of its vectors and presumed natural reservoirs, such as the rodent hutias and the small insectivorous mammal solenodon. The concept of species is discussed in the light of recent evaluations on criteria for defining bacterial species.

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  • Received : 02 Dec 2014
  • Accepted : 19 May 2015

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