Volume 91, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



We report three cases of lymphocutaneous infection caused by the thermally dimorphic fungus, from Australia's tropical Northern Territory. Two cases were acquired locally, making them the first to be reported from this region. All three cases presented with ulceration in the limb; however, the classical sporotrichoid spread was present only in the first two cases. Their occurrence within several weeks of each other was suggestive of a common source of environmental contamination such as hay used as garden mulch. Diagnoses were delayed in each case, with each patient having substantial exposure to ineffective antibiotics before the correct diagnosis was made. These cases bring the total number of reported sporotrichosis cases in Australia since 1951 to 199. Lessons from these cases are to consider the diagnosis of sporotrichosis in lesions of typical appearance, even in geographical settings from where this pathogen has not previously been reported.


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  1. Rivitti EA, Aoki V, , 1999. Deep fungal infections in tropical countries. Clin dermatol 17: 171190; discussion 105–106.[Crossref] [Google Scholar]
  2. Tobin EH, Jih WW, , 2001. Sporotrichoid lymphocutaneous infections: etiology, diagnosis and therapy. Am Fam Physician 63: 326332. [Google Scholar]
  3. Barros MB, de Almeida Paes R, Schubach AO, , 2011. Sporothrix schenckii and sporotrichosis. Clin Microbiol Rev 24: 633654.[Crossref] [Google Scholar]
  4. Sivagnanam S, Bannan AM, Chen SC, Ralph AP, , 2012. Sporotrichosis (Sporothrix schenckii infection) in the New South Wales mid-north coast, 2000–2010. Med J Aust 196: 588590.[Crossref] [Google Scholar]
  5. Robinson CF, Orban TD, , 1951. A case of regional lymphatic sporotrichosis. Aust J Dermatol 1: 142144.[Crossref] [Google Scholar]
  6. Barrack BB, Powell RE, , 1952. Sporotrichosis. Med J Aust 2: 624626. [Google Scholar]
  7. Minty CC, Mead M, McCaffrey MF, , 1956. Sporotrichosis: a case report from Queensland. Med J Aust 43: 704705. [Google Scholar]
  8. Mead M, Ridley MF, , 1957. Sporotrichosis and chromoblastomycosis in Queensland. Med J Aust 44: 192197. [Google Scholar]
  9. Durie EB, Frey D, Becke RF, , 1961. Sporotrichosis: report of a case from Sydney, Australia. Aust J Dermatol 6: 7172.[Crossref] [Google Scholar]
  10. O'Donnell JM, , 1962. A case of sporotrichosis. Med J Aust 49: 517518. [Google Scholar]
  11. Muir DB, Pritchard RC, , 1984. Sporothrix schenckii–incidence in the Sydney region. Australas J Dermatol 25: 2728.[Crossref] [Google Scholar]
  12. Robertson D, , 1967. Report of two cases of sporotrichosis of the face. Australas J Dermatol 9: 7682.[Crossref] [Google Scholar]
  13. Black RB, McAleer R, , 1975. A case of sporotrichosis in Western Australia. Australas J Dermatol 16: 3238.[Crossref] [Google Scholar]
  14. Auld JC, Beardmore GL, , 1979. Sporotrichosis in Queensland: a review of 37 cases at the Royal Brisbane Hospital. Australas J Dermatol 20: 1422.[Crossref] [Google Scholar]
  15. Beardmore GL, , 1979. Recalcitrant sporotrichosis: a report of a patient treated with various therapies including oral miconazole and 5-fluorocytosine. Australas J Dermatol 20: 1013.[Crossref] [Google Scholar]
  16. Bullpitt P, Weedon D, , 1978. Sporotrichosis: a review of 39 cases. Pathology 10: 249256.[Crossref] [Google Scholar]
  17. Conias S, Wilson P, , 1998. Epidemic cutaneous sporotrichosis: report of 16 cases in Queensland due to moldy hay. Australas J Dermatol 39: 3437.[Crossref] [Google Scholar]
  18. Moaven LD, Altman SA, Newnham AR, , 1999. Sporotrichosis mimicking necrotising arachnidism. Med J Aust 171: 685686. [Google Scholar]
  19. Feeney KT, Arthur IH, Whittle AJ, Altman SA, Speers DJ, , 2007. Outbreak of sporotrichosis, Western Australia. Emerg Infect Dis 13: 12281231.[Crossref] [Google Scholar]
  20. Dooley DP, Bostic PS, Beckius ML, , 1997. Spook house sporotrichosis. A point-source outbreak of sporotrichosis associated with hay bale props in a Halloween haunted-house. Arch Intern Med 157: 18851887.[Crossref] [Google Scholar]
  21. Pappas PG, Tellez I, Deep AE, Nolasco D, Holgado W, Bustamante B, , 2000. Sporotrichosis in Peru: description of an area of hyperendemicity. Clin Infect Dis 30: 6570.[Crossref] [Google Scholar]
  22. Currie BJ, Carapetis JR, , 2000. Skin infections and infestations in Aboriginal communities in northern Australia. Australas J Dermatol 41: 139143, quiz 44–45.[Crossref] [Google Scholar]
  23. Fisher D, Burrow J, Lo D, Currie BJ, , 1993. Cryptococcus neoformans in tropical northern Australia: predominantly variant gattii with good outcomes. Aust N Z J Med 23: 678682.[Crossref] [Google Scholar]
  24. Clinical and Laboratory Standards Institute, 2008. CLSI Reference Method for Broth Dilution Antifungal Susceptibility Testing of Filamentous Fungi: Approved Standard. Second edition. 2005. Available at: http://shopping.netsuite.com/c.1253739/site/Sample_pdf/M38A2_sample.pdf. [Google Scholar]
  25. Ellis DH, Davis S, Alexiou H, Handke R, Bartley R, , 2007. Descriptions of Medical Fungi. Second edition. ISBN: 9780959851267. Available at: http://www.mycology.adelaide.edu.au/downloads/Mycology-BookWEB.pdf. [Google Scholar]
  26. Tambini R, Farina C, Fiocchi R, Dupont B, Guého E, Delvecchio G, Mamprin F, Gavazzeni G, , 1996. Possible pathogenic role for Sporothrix cyanescens isolated from a lung lesion in a heart transplant patient. J Med Vet Mycol 34: 195198.[Crossref] [Google Scholar]
  27. Sigler L, Harris JL, Dixon DM, Flis AL, Salkin IF, Kemna M, Duncan RA, , 1990. Microbiology and potential virulence of Sporothrix cyanescens, a fungus rarely isolated from blood and skin. J Clin Microbiol 28: 10091015. [Google Scholar]
  28. Jackson L, Klotz SA, Normand RE, , 1990. A pseudoepidemic of Sporothrix cyanescens pneumonia occurring during renovation of a bronchoscopy suite. J Med Vet Mycol 28: 455459.[Crossref] [Google Scholar]
  29. Pegg GS, Dwyer CO, Carnegie AJ, Burgess TI, Wingfield MJ, Drenth A, , 2008. Quambalaria species associated with plantation and native eucalypts in Australia. Plant Pathol 57: 702714.[Crossref] [Google Scholar]
  30. Sutton DA, Fothergill AW, Rinaldi MG, , 1998. Guide to the Clinically Significant Fungi. First edition. Baltimore, MD: Williams and Wilkins. [Google Scholar]
  31. de Beer ZW, Harrington TC, Vismer HF, Wingfield BD, Wingfield MJ, , 2003. Phylogeny of the Ophiostoma stenoceras-Sporothrix schenckii complex. Mycologia 95: 434441.[Crossref] [Google Scholar]
  32. Paap T, Burgess TI, McComb JA, Shearer BL, St J Hardy GE, , 2008. Quambalaria species, including Q. coyrecup sp. nov., implicated in canker and shoot blight diseases causing decline of Corymbia species in the southwest of Western Australia. Mycol Res 112: 5769.[Crossref] [Google Scholar]
  33. Chen SC, Currie BJ, Campbell HM, Fisher DA, Pfeiffer TJ, Ellis DH, Sorrell TC, , 1997. Cryptococcus neoformans var. gattii infection in northern Australia: existence of an environmental source other than known host eucalypts. Trans R Soc Trop Med Hyg 91: 547550.[Crossref] [Google Scholar]
  34. Tang MM, Tang JJ, Gill P, Chang CC, Baba R, , 2012. Cutaneous sporotrichosis: a six-year review of 19 cases in a tertiary referral center in Malaysia. Int J Dermatol 51: 702708.[Crossref] [Google Scholar]
  35. Sharon VR, Kim J, Sudhakar S, Fung MA, Maniar A, , 2013. Disseminated cutaneous sporotrichosis. Lancet Infect Dis 13: 95.[Crossref] [Google Scholar]
  36. de Lima Barros MB, Schubach AO, de Vasconcellos Carvalhaes de Oliveira R, Martins EB, Teixeira JL, Wanke B, , 2011. Treatment of cutaneous sporotrichosis with itraconazole–study of 645 patients. Clin Infect Dis 52: e200e206.[Crossref] [Google Scholar]
  37. Marimon R, Serena C, Gene J, Cano J, Guarro J, , 2008. In vitro antifungal susceptibilities of five species of sporothrix. Antimicrob Agents Chemother 52: 732734.[Crossref] [Google Scholar]

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  • Received : 23 Jul 2014
  • Accepted : 06 Aug 2014
  • Published online : 03 Dec 2014

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