Volume 91, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



A new surgical approach (subadventitial cystectomy) has been developed for liver hydatid disease. We retrospectively compared clinical outcomes and immune status 24 months after a subadventitial cystectomy with traditional surgical approaches. Patients with liver hydatid cysts were treated with a subadventitial cystectomy ( = 11), pericystectomy ( = 16), partial pericystectomy ( = 18), or hepatic resection ( = 12). By the end of the follow-up period, the subadventitial cystectomy group had the fewest post-operative complications and shortest hospital stays. Two recurrences occurred: one recurrence after partial pericystectomy and one recurrence after pericystectomy. The total immunoglobulin E (IgE) level decreased significantly in the subadventitial cystectomy group. The post-surgery IgG level was lower in the subadventitial cystectomy than the pericystectomy and partial pericystectomy groups. In conclusion, subadventitial cystectomy completely removes the parasite, causing lower complication rates and lower immune reactions.


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  1. Caremani M, Benci A, Maestrini R, Rossi G, Menchetti D, , 2006. Abdominal cystic hydatid disease (CHD): classification of sonographic appearance and response to treatment. J Clin Ultrasound 24: 491500.[Crossref] [Google Scholar]
  2. Voros D, Katsarelias D, Polymeneas G, Polydorou A, Pistiolis L, Kalovidouris A, Gouliamos A, , 2007. Treatment of hydatid liver disease. Surg Infect (Larchmt) 8: 621627.[Crossref] [Google Scholar]
  3. Safioleas MC, Misiakos EP, Kouvaraki M, Stamatakos MK, Manti CP, Felekouras ES, , 2006. Hydatid disease of the liver: a continuing surgical problem. Arch Surg 141: 11011108.[Crossref] [Google Scholar]
  4. Qi Zheng, Samantha Vanderslott, Bin Jiang, LiLi Xu, Cong-Shan Liu, LeLe Huo, LiPing Duan, NingBo Wu, ShiZhu Li, ZhiGui Xia, WeiPing Wu, Wei Hu, Hao-Bing Zhang, , 2013. Research gaps for three main tropical diseases in the People?s Republic of China. Infectious Diseases of Poverty 2: 15.[Crossref] [Google Scholar]
  5. Zhang W, Zhang Z, Wu W, Shi B, Li J, Zhou X, Wen H, McManus DP, , 2014. Epidemiology and control of echinococcosis in central Asia, with particular reference to the People's Republic of China. Acta Trop. doi:10.1016/j.actatropica.2014.03.014. [Google Scholar]
  6. Junghanss T, da Silva AM, Horton J, Chiodini PL, Brunetti E, , 2008. Clinical management of cystic echinococcosis: state of the art, problems, and perspectives. Am J Trop Med Hyg 79: 301311. [Google Scholar]
  7. Smego RA, Jr Sebanego P, , 2005. Treatment options for hepatic cystic echinococcosis. Int J Infect Dis 9: 6976.[Crossref] [Google Scholar]
  8. Prousalidis J, Kosmidis C, Fahantidis E, Harlaftis N, Aletras O, , 2004. Surgical treatment of multiple cystic echinococcosis. HPB (Oxford) 6: 110114.[Crossref] [Google Scholar]
  9. Vuitton DA, Wen H, , 2007. Treatment of cystic echinococcosis: a combination of general goals and rules, individual decisions and indications. Neth J Med 65: 8688. [Google Scholar]
  10. Peng X, Li J, Wu X, Zhang S, Niu J, Chen X, Yao J, Sun H, , 2006. Detection of Osteopontin in the pericyst of human hepatic Echinococcus granulosus . Acta Trop 100: 163171.[Crossref] [Google Scholar]
  11. da Silva AM, , 2010. Human echinococcosis: a neglected disease. Gastroenterol Res Pract 2010: 583297.[Crossref] [Google Scholar]
  12. Da Silva AM, , 2011. Hydatid cyst/cystic echinococcosis: anatomical and surgical nomenclature and method to quantify the cyst content solidification. Chin Med J (Engl) 124: 28062812. [Google Scholar]
  13. Hoda SA, Hoda RS, , 2002. Images in pathology: intraoperative cytology of hydatid cyst. Int J Surg Pathol 10: 209.[Crossref] [Google Scholar]
  14. El Malki HO, Souadka A, El Mejdoubi Y, Zakri B, Benkabbou A, Mohsine R, Ifrine L, Belkouchi A, , 2007. Surgery in intra-abdominal ruptured hydatid cyst. World J Surg 31: 1525.[Crossref] [Google Scholar]
  15. Aydin U, Yazici P, Onen Z, Ozsoy M, Zeytunlu M, Kiliç M, Coker A, , 2008. The optimal treatment of hydatid cyst of the liver: radical surgery with a significant reduced risk of recurrence. Turk J Gastroenterol 19: 3339. [Google Scholar]

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  • Received : 23 Mar 2014
  • Accepted : 24 Jun 2014
  • Published online : 01 Oct 2014

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