1921
Volume 91, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

A fatal case of melioidosis was diagnosed in Ohio one month after culture results were initially reported as a species. To identify a source of infection and assess risk in patient contacts, we abstracted patient charts; interviewed physicians and contacts; genetically characterized the isolate; performed a antibody indirect hemagglutination assay on household contacts and pets to assess seropositivity; and collected household plant, soil, liquid, and insect samples for culturing and real-time polymerase chain reaction testing. Family members and pets tested were seronegative for . Environmental samples were negative by real-time polymerase chain reaction and culture. Although the patient never traveled internationally, the isolate genotype was consistent with an isolate that originated in Southeast Asia. This investigation identified the fifth reported locally acquired non-laboratory melioidosis case in the contiguous United States. Physicians and laboratories should be aware of this potentially emerging disease and refer positive cultures to a Laboratory Response Network laboratory.

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2014-10-01
2017-11-23
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References

  1. Wiersinga WJ, Currie BJ, Peacock SJ, , 2012. Melioidosis. N Engl J Med 367: 10351044.[Crossref]
  2. Inglis TJJ, Rolim DB, Sousa AD, , 2006. Melioidosis in the Americas. Am J Trop Med Hyg 75: 947954.
  3. Currie BJ, , 2003. Melioidosis: an important cause of pneumonia in residents of and travelers returned from endemic regions. Eur Respir J 22: 542550.[Crossref]
  4. Inglis TJ, Rolim DB, Rodriguez JI, , 2006. Clinical guideline for diagnosis and management of melioidosis. Rev Inst Med Trop Sao Paulo 48: 14.[Crossref]
  5. Limmathurotsakul D, Kanoksil M, Wuthiekanun V, Kitphati R, deStavola B, Day NP, Peacock SJ, , 2013. Activities of daily living associated with acquisition of melioidosis in northeast Thailand: a matched case-control study. PLoS Negl Trop Dis 7: 16.
  6. Cheng AC, Currie BJ, , 2005. Melioidosis: epidemiology, pathophysiology, and management. Clin Microbiol Rev 18: 383416.[Crossref]
  7. Currie BJ, Fisher DA, Howard DM, Burrow JN, Selvanayagam S, Snelling PL, Anstey NM, Mayo MJ, , 2000. The epidemiology of melioidosis in Australia and Papua New Guinea. Acta Trop 74: 121127.[Crossref]
  8. Njauy V, Lemeshev Y, Sadkowski L, Crawford G, , 2005. Cutaneous melioidosis in a man who was taken as a prisoner of war by the Japanese during World War II. J Clin Microbiol 43: 970972.[Crossref]
  9. Currie BJ, Ward L, Cheng AC, , 2010. The epidemiology and clinical spectrum of melioidosis: 540 cases from the 20 year Darwin prospective study. PLoS Negl Trop Dis 4: 111.[Crossref]
  10. Alexander AD, Huxsoll DL, Warner ARJ, Shepler V, Dorsey A, , 1970. Serological diagnosis of human melioidosis with indirect hemagglutination and complement fixation tests. J Appl Microbiol 20: 825833.
  11. Novak RT, Glass MB, Gee JE, Gal D, Mayo MJ, Currie BJ, Wilkins PP, , 2006. Development and evaluation of a real-time PCR assay targeting the type III secretion system of Burkholderia pseudomallei . J Clin Microbiol 44: 8590.[Crossref]
  12. Godoy D, Randle G, Simpson AJ, Aanensen DM, Pitt TL, Kinoshita R, Spratt BG, , 2003. Multilocus sequence typing and evolutionary relationships among the causative agents of melioidosis and glanders, Burkholderia pseudomallei and Burkholderia mallei . J Clin Microbiol 41: 20682079.[Crossref]
  13. Liguori AP, Warrington SD, Ginther JL, Pearson T, Bowers J, Glass MB, Mayo M, Wuthiekanun V, Engelthaler D, Peacock SJ, Currie BJ, Wagner DM, Keim P, Tuanyok A, , 2011. Diversity of 16S-23S rDNA internal transcribed spacer (ITS) reveals phylogenetic relationships in Burkholderia pseudomallei and its near-neighbors. PLoS ONE 6: e29323.[Crossref]
  14. Harris PNA, Ketheesan N, Owens L, Norton RE, , 2009. Clinical features that affect indirect-hemagglutination-assay responses to Burkholderia pseudomallei . Clin Vaccine Immunol 16: 924930.[Crossref]
  15. Brook MD, Currie B, Desmarcheller PM, , 1997. Isolation and identification of Burkholderia pseudomallei from soil using selective culture techniques and the polymerase chain reaction. J Appl Microbiol 82: 589596.[Crossref]
  16. Kaestli M, Mayo M, Harrington G, Watt F, Hill J, Gal D, Currie BJ, , 2007. Sensitive and specific molecular detection of Burkholderia pseudomallei, the causative agent of melioidosis, in the soil of tropical northern Australia. Appl Environ Microbiol 73: 68916897.[Crossref]
  17. Garry MW, Koch ML, , 1951. Chronic melioidosis: bacteriologic and clinical correlation in diagnosis. J Lab Clin Med 38: 374383.
  18. Osteraas GR, Hardman JM, Bass JW, Wilson C, , 1971. Neonatal melioidosis. Am J Dis Child 122: 446448.
  19. Currie BJ, Fisher DA, Howard DM, Burrow JN, Lo D, Selva-nayagam S, Anstey NM, Huffam SE, Snelling PL, Marks PJ, Stephens DP, Lum GD, Jacups SP, Krause VL, , 2000. Endemic melioidosis in tropical northern Australia: a 10-year prospective study and review of the literature. Clin Infect Dis 31: 981986.[Crossref]
  20. McCormick JB, Sexton DJ, McMurray JG, Carey E, Hayes P, Feldman RA, , 1975. Human-to-human transmission of Pseudomonas pseudomallei . Ann Intern Med 83: 512513.[Crossref]
  21. Zehnder AM, Hawkins MG, Koshi MA, Lifland B, Byrne BA, Swanson AA, Rood MP, Gee JE, Elrod MG, Beesley CA, Blaney DD, Ventura J, Hoffmaster AR, Beeler ES, , 2014. Burkholderia pseudomallei in 2 pet iguanas, California, USA. Emerg Infect Dis 20: 304306.[Crossref]
  22. Stewart T, Engelthaler DM, Blaney DD, Tuanyok A, Wangsness E, Smith TL, Pearson T, Komatsu KK, Keim P, Currie BJ, Levy C, Sunenshine R, , 2011. Epidemiology and investigation of melioidosis, southern Arizona. Emerg Infect Dis 17: 12861288.[Crossref]
  23. Centers for Disease Control and Prevention, 2013. The Laboratory Response Network: Partners in Preparedness. Available at: http://www.bt.cdc.gov/lrn/. Accessed January 2, 2014.
  24. American Society of Microbiology, 2014. Sentinel Level Clinical Laboratory Guidelines for Suspected Agent of Bioterrorism and Emerging Infectious Diseases: Glanders (Burkholderia mallei) and Melioidosis (Burkholderia pseudomallei). Available at: http://www.asm.org/images/PSAB/Burkholderia. Accessed January 2, 2014.
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  • Received : 20 Mar 2014
  • Accepted : 15 Jun 2014

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