Volume 91, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



There are limited data about the epidemiology of fascioliasis in Cuzco, Peru. We studied children 3–12 years old from six communities in the highlands of Cuzco to evaluate the epidemiology of fascioliasis; 227 children were included, one-half were female, the mean age was 7.5 (±2.6) years, and 46.2±% had one or more parasites, including (9.7%), (12.8%), (9.3%), (1.3%), hookworm (1.8%), (0.9%), and (27.8%). was associated with the number of siblings in the household, drinking untreated water, and giardiasis. Eosinophilia was encountered in 21% of children and more common in those drinking untreated water at home and those infected with a parasite, but the differences were not significant. Eating water plants was not associated with or eosinophilia. Fascioliasis and eosinophilia were common in the highlands of Cuzco. Fascioliasis was associated with socioeconomic factors and drinking water.


Article metrics loading...

The graphs shown below represent data from March 2017
Loading full text...

Full text loading...



  1. World Health Organization, 2007. Fascioliasis: Infection with the “Neglected” Neglected Worms. Available at: http://www.who.int/neglected_diseases/integrated_media/integrated_media_fascioliasis/en. Accessed March 18, 2014. [Google Scholar]
  2. Mas-Coma S, Valero MA, Bargues MD, , 2009. Chapter 2: Fasciola, lymnaeids, and human fascioliasis, with a global overview of disease transmission, epidemiology, evolutionary genetics, molecular epidemiology, and control. Adv Parasitol 69: 41146.[Crossref] [Google Scholar]
  3. Cabada MM, White AC, Jr, 2012. New developments in the epidemiology, diagnosis, and treatment of fascioliasis. Curr Opin Infect Dis 25: 518522.[Crossref] [Google Scholar]
  4. Marcos LA, Maco V, Florencio L, Terashima A, Samalvides F, Espinoza JR, Miranda E, Tantaleán M, Gotuzzo E, , 2005. Altas tasas de prevalencia de fasciolosis humana en el Peru: una enfermedad emergente. Rev Peru Enferm Infecc Trop 3: 813. [Google Scholar]
  5. Parkinson M, O'Neill SM, Dalton JP, , 2006. Endemic human fasciolosis in the Bolivian Altiplano. Epidemiol Infect 26: 16. [Google Scholar]
  6. Marcos LA, Maco V, Terashima A, Samalvides F, Gotuzzo E, , 2002. Caracteristicas clínicas de la infección crónica por Fasciola hepatica en niños. Rev Gastroenterol Peru 22: 228233. [Google Scholar]
  7. Marcos LA, Maco V, Castillo M, Terashima A, Serpa R, Gotuzzo E, , 2005. Reporte de casos de fasciolasis en el Instituto Especializado de Salud del Nino, Lima-Peru (1988–2003). Rev Gastroenterol Peru 25: 198205. [Google Scholar]
  8. El-Shazly AM, El-Nahas HA, Abdel-Mageed AA, El Beshbishi SN, Azab MS, Abou El Hasan M, Arafa WA, Morsy TA, , 2005. Human fascioliasis and anaemia in Dakahlia governorate, Egypt. J Egypt Soc Parasitol 35: 421432. [Google Scholar]
  9. Lopez M, White AC, Cabada MM, , 2012. Burden of Fasciola hepatica infection among children from Paucartambo in Cuzco, Peru. Am J Trop Med Hyg 86: 481485.[Crossref] [Google Scholar]
  10. Karahocagil MK, Akdeniz H, Sunnetcioglu M, Cicek M, Mete R, Akman N, Ceylan E, Karsen H, Yapici K, , 2011. A familial outbreak of fascioliasis in eastern Anatolia: a report with review of literature. Acta Trop 118: 177183.[Crossref] [Google Scholar]
  11. Marcos LA, Terashima A, Leguia G, Canales M, Espinoza JR, Gotuzzo E, , 2007. La infeccion por Fasciola hepatica en el Peru: una enfermedad emergente. Rev Gastroenterol Peru 27: 389396. [Google Scholar]
  12. Mas-Coma S, , 2005. Epidemiology of fascioliasis in human endemic areas. J Helminthol 79: 207216.[Crossref] [Google Scholar]
  13. Marcos L, Maco V, Samalvides F, Terashima A, Espinoza JR, Gotuzzo E, , 2006. Risk factors for Fasciola hepatica infection in children: a case-control study. Trans R Soc Trop Med Hyg 100: 158166.[Crossref] [Google Scholar]
  14. Zumaquero-Rıos JL, Sarracent-Perez J, Rojas-Garcıa R, Rojas-Rivero L, Martınez-Tovilla Y, Valero MA, Mas-Coma S, , 2013. Fascioliasis and intestinal parasitoses affecting schoolchildren in Atlixco, Puebla State, Mexico: epidemiology and treatment with nitazoxanide. PLoS Negl Trop Dis 7: e2553.[Crossref] [Google Scholar]
  15. Maco-Flores V, Marcos-Raymundo L, Terashima-Iwashita A, Samalbvides-Cuba F, Miranda-Sanchez E, Espinoza-Babilon J, Gotuzzo-Herencia J, , 2002. Fas-2 ELISA and the Rapid Sedimentation Technique Modified by Lumbreras for Fasciola Hepatica Infection Diagnosis. Available at: http://www.scielo.org.pe/pdf/rmh/v13n2/v13n2ao3.pdf. Accessed March 18, 2014. [Google Scholar]
  16. Lozoff B, Beard J, Connor J, Barbara F, Georgieff M, Schallert T, , 2006. Long-lasting neural and behavioral effects of iron deficiency in infancy. Nutr Rev 64 (Suppl 2): S34S43.[Crossref] [Google Scholar]
  17. World Health Organization, 2013. Fascioliasis Diagnosis, Treatment and Control Strategy. Available at: http://www.who.int/foodborne_trematode_infections/fascioliasis/fascioliasis_diagnosis/en/index.html. Accessed March 11, 2014. [Google Scholar]
  18. Villegas F, Angles R, Barrientos R, Barrios G, Valero MA, Hamed K, Grueninger H, Ault SK, Montresor A, Engels D, Mas-Coma S, Gabrielli AF, , 2012. Administration of triclabendazole is safe and effective in controlling fascioliasis in an endemic community of the Bolivian Altiplano. PLoS Negl Trop Dis 76: e1720.[Crossref] [Google Scholar]
  19. Taylor-Robinson DC, Maayan N, Soares-Weiser K, Donegan S, Garner P, , 2012. Deworming drugs for soil-transmitted intestinal worms in children: effects on nutritional indicators, haemoglobin and school performance. Cochrane Database Syst Rev 11: CD000371. [Google Scholar]
  20. Awasthi S, Peto R, Read S, Richards SM, Pande V, Bundy D, DEVTA (Deworming and Enhanced Vitamin A) Team; , 2013. Population deworming every 6 months with albendazole in 1 million pre-school children in north India: DEVTA, a cluster-randomized trial. Lancet 381: 14781486.[Crossref] [Google Scholar]
  21. Esteban JG, Gonzalez C, Bargues MD, Angles R, Sánchez C, Náquira C, Mas-Coma S, , 2002. High fascioliasis infection in children linked to a man-made irrigation zone in Peru. Trop Med Int Health 7: 339348.[Crossref] [Google Scholar]
  22. Esteban JG, Flores A, Aguirre C, Strauss W, Angles R, Mas-Coma S, , 1997. Presence of very high prevalence and intensity of infection with Fasciola hepatica among Aymara children from the northern Bolivian Altiplano. Acta Trop 66: 114.[Crossref] [Google Scholar]
  23. Heukelbach J, Poggensee G, Winter B, Wilcke T, Kerr-Pontes LR, Feldmeier H, , 2006. Leukocytosis and blood eosinophilia in a polyparasitised population in north-eastern Brazil. Trans R Soc Trop Med Hyg 100: 3240.[Crossref] [Google Scholar]
  24. Fica A, Dabanch J, Farias C, Castro M, Jercic MI, Weitzel T, , 2012. Acute fascioliasis—clinical and epidemiological features of four patients in Chile. Clin Microbiol Infect 18: 9196.[Crossref] [Google Scholar]
  25. Kaya M, Beştaş R, Çetin S, , 2011. Clinical presentation and management of Fasciola hepatica infection: single-center experience. World J Gastroenterol 17: 48994904.[Crossref] [Google Scholar]
  26. Esteban JG, Flores A, Angles R, Mas-Coma S, , 1999. High endemicity of human fascioliasis between Lake Titicaca and La Paz valley, Bolivia. Trans R Soc Trop Med Hyg 93: 151156.[Crossref] [Google Scholar]

Data & Media loading...

  • Received : 19 Mar 2014
  • Accepted : 06 Aug 2014
  • Published online : 05 Nov 2014

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error