Volume 91, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



An association between late-stage hepatosplenic schistosomiasis and endomyocardial fibrosis (EMF) has been suggested but not proven. We present the case of a 12-year-old Ugandan boy with striking comorbidities, including advanced periportal fibrosis caused by infection and right ventricular EMF, and discuss the possible correlation between both diseases.


Article metrics loading...

The graphs shown below represent data from March 2017
Loading full text...

Full text loading...



  1. Gryseels B, Polman K, Clerinx J, Kestens L, , 2006. Human schistosomiasis. Lancet 368: 11061118.[Crossref] [Google Scholar]
  2. Rashwan MA, Ayman M, Ashour S, Hassanin MM, Zeina AA, , 1995. Endomyocardial fibrosis in Egypt: an illustrated review. Br Heart J 73: 284289.[Crossref] [Google Scholar]
  3. Bukhman G, Ziegler J, Parry E, , 2008. Endomyocardial fibrosis: still a mystery after 60 years. PLoS Negl Trop Dis 2: e97.[Crossref] [Google Scholar]
  4. Vijayaraghavan G, Sivasankaran S, , 2012. Tropical endomyocardial fibrosis in India: a vanishing disease! Indian J Med Res 136: 729738. [Google Scholar]
  5. Mocumbi AO, Falase AO, , 2014. Republished: recent advances in the epidemiology, diagnosis and treatment of endomyocardial fibrosis in Africa. Postgrad Med J 90: 4854.[Crossref] [Google Scholar]
  6. Rutakingirwa M, Ziegler JL, Newton R, Freers J, , 1999. Poverty and eosinophilia are risk factors for endomyocardial fibrosis (EMF) in Uganda. Trop Med Int Health 4: 229235.[Crossref] [Google Scholar]
  7. Andy JJ, Ogunowo PO, Akpan NA, Odigwe CO, Ekanem IA, Esin RA, , 1998. Helminth associated hypereosinophilia and tropical endomyocardial fibrosis (EMF) in Nigeria. Acta Trop 69: 127140.[Crossref] [Google Scholar]
  8. Carneiro R de C, Santos AL, Brant LC, Rabelo FT, Ligeiro CM, Barcelos IP, Silva VB, Silva VS, Nunes M do C, , 2011. Endomyocardial fibrosis associated with mansoni schistosomiasis. Rev Soc Bras Med Trop 44: 644645.[Crossref] [Google Scholar]
  9. Sousa-Figueiredo JC, Pleasant J, Day M, Betson M, Rollinson D, Montresor A, Kazibwe F, Kabatereine NB, Stothard JR, , 2010. Treatment of intestinal schistosomiasis in Ugandan preschool children: best diagnosis, treatment efficacy and side-effects, and an extended praziquantel dosing pole. In Health 2: 103113.[Crossref] [Google Scholar]
  10. Richter J, Hatz C, Campagne G, Bergquist NR, Jenkins JM, UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases; , 2000. Ultrasound in schistosomiasis: a practical guide to the standard use of ultrasonography for assessment of schistosomiasis-related morbidity. Proceedings of the Second International Workshop, October 22–26, 1996; Niamey, Niger. [Google Scholar]
  11. Mocumbi AO, Ferreira MB, Sidi D, Yacoub MH, , 2008. A population study of endomyocardial fibrosis in a rural area of Mozambique. N Engl J Med 359: 4349.[Crossref] [Google Scholar]
  12. Connor DH, Somers K, Hutt MS, Manion WC, D'Arbela PG, , 1967. Endomyocardial fibrosis in Uganda (Davies' disease). 1. An epidemiologic, clinical, and pathologic study. Am Heart J 74: 687709.[Crossref] [Google Scholar]
  13. Barbosa MM, Lamounier JA, Oliveira EC, Souza MV, Marques DS, Lambertucci JR, , 1998. Short report: endomyocardial fibrosis and cardiomyopathy in an area endemic for schistosomiasis. Am J Trop Med Hyg 58: 2627. [Google Scholar]

Data & Media loading...

  • Received : 16 Mar 2014
  • Accepted : 28 May 2014
  • Published online : 01 Oct 2014

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error