1921
Volume 93, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

Confusion between salt/base forms of primaquine may result in malaria prophylaxis failure. During 1995–2011, there were 14 malaria cases in Israel despite primaquine primary prophylaxis. In 6/14 cases, primaquine was underdosed because of confusion between salt and base forms, including two cases. Primaquine labeling clarification may be lifesaving.

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References

  1. Schlitzer M, , 2007. Malaria chemotherapeutics part I: history of antimalarial drug development, currently used therapeutics, and drugs in clinical development. Chem Med Chem 2: 944986.[Crossref] [Google Scholar]
  2. Hill DR, Baird JK, Parise ME, Lewis LS, Ryan ET, Magill AJ, , 2006. Primaquine: report from CDC expert meeting on malaria chemoprophylaxis I. Am J Trop Med Hyg 75: 402415. [Google Scholar]
  3. Kathrine RT, Paul MA, Stefanie FS, , 2014. Infectious diseases related to travel: malaria. CDC Health Information for International Travel 2014. Centers for Disease Control and Prevention (CDC). Available at: http://wwwnc.cdc.gov/travel/page/yellowbook-home-2014. Accessed February 4, 2015. [Google Scholar]
  4. U.S. Pharmacopeial Convention (USP). Monograph Naming Policy for Salt Drug Substances in Drug Products and Compounded Preparations. Available at: http://www.usp.org/sites/default/files/usp_pdf/EN/2014-12-01_nom_guidelines.pdf. Last revision on: December 1, 2014. [Google Scholar]
  5. Schwartz E, Schwartz E, , 2009. Malaria in travelers: epidemiology, clinical aspects and treatment. , ed. Tropical Diseases in Travelers. New York, NY: John Wiley and Sons.[Crossref] [Google Scholar]
  6. State of Israel Ministry of Health, 2013. Guidelines for Persons Travelling Overseas, 2013 Update, Epidemiology Division, Public Health Services (Hebrew). Available at: http://www.health.gov.il/Subjects/vaccines/Vaccines_abroad/Documents/travel2013.pdf. Accessed December 10, 2013. [Google Scholar]
  7. Thomsen LA, Winterstein AG, Sondergaard B, Haugbolle LS, Melander A, , 2007. Systematic review of the incidence and characteristics of preventable adverse drug events in ambulatory care. Ann Pharmacother 41: 14111426.[Crossref] [Google Scholar]
  8. Latif A, Rawat N, Pustavoitau A, Pronovost PJ, Pham JC, , 2013. National study on the distribution, causes, and consequences of voluntarily reported medication errors between the ICU and non-ICU settings. Crit Care Med 41: 389398.[Crossref] [Google Scholar]
  9. Avery AJ, Ghaleb M, Barber N, Dean Franklin B, Armstrong SJ, Serumaga B, Dhillon S, Freyer A, Howard R, Talabi O, Mehta RL, , 2013. The prevalence and nature of prescribing and monitoring errors in English general practice: a retrospective case note review. Br J Gen Pract 63: e543e553.[Crossref] [Google Scholar]
  10. Singh K, Wester WC, Trenholme GM, , 2003. Problems in the therapy for imported malaria in the United States. Arch Intern Med 163: 20272030.[Crossref] [Google Scholar]
  11. Dorlo TP, Kager PA, , 2008. Pentamidine dosage: a base/salt confusion. PLoS Negl Trop Dis 2: e225.[Crossref] [Google Scholar]
  12. Schwartz E, Regev-Yochay G, Kurnik D, , 2000. Short report: a consideration of primaquine dose adjustment for radical cure of Plasmodium vivax malaria. Am J Trop Med Hyg 62: 393395. [Google Scholar]
  13. Shihmanter R, Nulman I, Goland S, Caspi A, Bar-Haim A, Harary I, Berkovitch M, Arcavi L, , 2014. Variation in the CYP2D6 genotype is not associated with carvedilol dose changes in patients with heart failure. J Clin Pharm Ther 39: 432438.[Crossref] [Google Scholar]
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  • Received : 19 Feb 2014
  • Accepted : 23 Feb 2015

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