1921
Volume 90, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

Cases of melioidosis and glanders are rare in the United States, but the etiologic agents of each disease ( and , respectively) are classified as Tier 1 select agents because of concerns about their potential use as bioterrorism agents. A rapid, highly sensitive, and portable assay for clinical laboratories and field use is required. Our laboratory has further evaluated a latex agglutination assay for its ability to identify and isolates. This assay uses a monoclonal antibody that specifically recognizes the capsular polysaccharide produced by and , but is absent in closely related species. A total of 110 and were tested, and 36 closely related species. The latex agglutination assay was positive for 109 of 110 (99.1% sensitivity) and isolates tested.

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2014-06-04
2017-09-22
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  • Received : 10 Jan 2014
  • Accepted : 02 Mar 2014

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