1921
Volume 91, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

Myocarditis is an uncommon manifestation of dengue fever. We describe a case of a 69-year-old Hispanic male who presented to an emergency room in New York City 3 days after returning from a trip to the Dominican Republic complaining of a 1-day history of chest pain and fever. His first electrocardiogram showed a new left bundle branch block, and initial cardiac enzymes included troponin of 5 ng/dL, creatine kinase-MB of 9 ng/mL, and myoglobin of 234 ng/mL. Dengue fever antibodies were found to be elevated: immunoglobulin M (IgM) titer was 2.48 (reference range < 0.9), and immunoglobulin G (IgG) titer was 4.26 (reference range < 0.9). The patient was diagnosed with myocarditis caused by dengue fever. He improved after 1 week with conservative management in a telemetry unit and was discharged home.

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References

  1. WHO, 2009. Dengue, Guidelines for Diagnosis, Treatment, Prevention and Control—New Edition. Geneva: World Health Organization.
    [Google Scholar]
  2. Srikiatkhachorn A, Rothman AL, Gibbons RV, Sittisombut N, Malasit P, Ennis FA, Nimmannitya S, Kalayanarooj S, 2011. Dengue—how best to classify it. Clin Infect Dis 53: 563567.[Crossref]
    [Google Scholar]
  3. Gulati S, Maheshwari A, 2007. Atypical manifestations of dengue. Trop Med Int Health 12: 10871095.[Crossref]
    [Google Scholar]
  4. Nagaratnam N, Siripala K, de Silva N, 1973. Arbovirus (dengue type) as a cause of acute myocarditis and pericarditis. Br Heart J 35: 204206.[Crossref]
    [Google Scholar]
  5. Kularatne SA, Pathirage MM, Medagama UA, Gunasena S, Gunasekara MB, 2006. Myocarditis in three patients with dengue type 3 infection. Ceylon Med J 51: 7576.
    [Google Scholar]
  6. Lee IK, Lee WH, Liu JW, Yang KD, 2010. Acute myocarditis in dengue hemorrhagic fever: a case report and a review of cardiac complications in dengue-affected patients. Int J Infect Dis 14: e919e922.[Crossref]
    [Google Scholar]
  7. Lee CH, Teo C, Low AF, 2009. Fulminant dengue myocarditis masquerading as acute myocardial infarction. Int J Cardiol 136: e69e71.[Crossref]
    [Google Scholar]
  8. Salgado DM, Eltit JM, Mansfield K, Panqueba C, Castro D, Vega MR, Xhaja K, Schmidt D, Martin KJ, Allen PD, Rodriguez JA, Dinsmore JH, Lopez JR, Bosch I, 2010. Heart and skeletal muscle are targets of dengue virus infection. Pediatr Infect Dis J 29: 238242.[Crossref]
    [Google Scholar]
  9. Premaratna R, Rodrigo KM, Anuratha A, de Alwis VK, Perera UD, de Silva HJ, 2012. Repeated dengue shock syndrome and ‘dengue myocarditis’ responding dramatically to a single dose of methyl prednisolone. Int J Infect Dis 16: e565e569.[Crossref]
    [Google Scholar]
  10. Srichaikul T, Punyagupta S, Sorakhunpipitkul L, Udomsubpayakul U, 2011. Adjunctive corticosteroid therapy in 149 grade II (non-shock) adult DHF patients: an analysis during January 2008–February 2010. J Med Assoc Thai 94: 14191423.
    [Google Scholar]
  11. Tricou V, Minh NN, Van TP, 2010. A randomized controlled trial of chloroquine for the treatment of dengue in Vietnamese adults. PLoS Negl Trop Dis 4: e785.[Crossref]
    [Google Scholar]
  12. Centers for Disease Control and Prevention, 2012. How to Reduce Your Risk of Dengue Infection. Available at: http://www.cdc.gov/dengue/prevention/index.html. Accessed June 17, 2012.
    [Google Scholar]
  13. Halstead SB, 2013. Dengue: the syndromic basis to pathogenesis research. Inutility of the 2009 WHO case definition. Am J Trop Med Hyg 88: 212215.[Crossref]
    [Google Scholar]
  14. Chaterji S, Allen JC Jr, Chow A, Leo Y-S, Ooi E-E, 2011. Evaluation of the NS1 rapid test and the WHO dengue classification schemes for use as bedside diagnosis of acute dengue fever in adults. Am J Trop Med Hyg 84: 224228.[Crossref]
    [Google Scholar]
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  • Received : 01 Nov 2013
  • Accepted : 14 Feb 2014
  • Published online : 02 Jul 2014
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