1921
Volume 91, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

The chromosome contains a large variety and number of insert sequences that have resulted in frequent chromosome rearrangement events. To identify the chromosomal rearrangement features of strains from five typical plague foci in China and study spontaneous DNA rearrangements potentially stabilized in certain lineages of genomes, we examined the linking mode of locally collinear blocks (LCBs) in 30 strains by a polymerase chain reaction-based method. Our results suggest most strains have relatively stable chromosomal arrangement patterns, and these rearrangement characteristics also have a very close relationship with the geographical origin. In addition, some LCB linking modes are only present in specific strains. We conclude chromosome rearrangement patterns may reflect the genetic features of specific geographical areas and can be applied to distinguish isolates; furthermore, most of the rearrangement events are stable in certain lineages of genomes.

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2014-10-01
2017-11-22
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Supplementary Data

Supplementary PDF

  • Received : 24 Aug 2013
  • Accepted : 02 Jun 2014

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