Volume 90, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



To determine the influence of onchocercal eye disease on the intraocular pressure of the Yanomami Tribe Aratha-ú of Roraima State, Brazil, considered endemic for onchocerciasis, a total of 86 patients were submitted to an ophthalmologic exam that included external examination, slit lamp examination, intraocular pressure measurement, and a fundus ophthalmoscope examination. A high prevalence of onchocerciasis-related eye lesions was encountered in 68.6% of the patients. Punctate keratitis and microfilariae in the anterior chamber were found in ∼28%. The mean of intraocular eye pressure found was 10.47 mm of Hg.


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  1. Evans TG, , 1995. Socioeconomic consequences of blinding onchocerciasis in West Africa. Bull World Health Organ 73: 495506. [Google Scholar]
  2. World Health Organization, 1995. Onchocerciasis Control Programme in West Africa. Report of the WHO, Geneva. [Google Scholar]
  3. Centers for Disease Control and Prevention, 2013. Progress toward elimination of onchocerciasis in the Americas: 1993–2012. MMWR Morb Mortal Wkly Rep 62: 405408. [Google Scholar]
  4. Egbert PR, Jacobson DW, Fiadoyor S, Dadzie P, Ellingson KD, , 2005. Onchocerciasis: a potential risk factor for glaucoma. Br J Ophthalmol 89: 796798.[Crossref] [Google Scholar]
  5. Chester P, Clifton R, Wayne E, , 1992. Parasitología Clínica. Salvat Editors. Second Edition. México, D.F. Editorial Interamericana. [Google Scholar]
  6. Wolfs RC, Borger PH, Ramrattan RS, Klaver CC, Hulsman CA, Hofman A, Vingerling JR, Hitchings RA, de Jong PT, , 2000. Changing views on open-angle glaucoma: definitions and prevalences: The Rotterdam Study. Invest Ophthalmol Vis Sci 41: 33093321. [Google Scholar]
  7. Herzog Neto G, Jaegger K, Marchon-Silva V, Calvão-Britto RH, Vieira JB, Banic DM, Maia-Herzog M, , 2009. Eye lesions due to onchocerciasis: a clinica study in the Aratha-ú, Yanomami tribe, Roraima State, Brazil. Acta Trop 111: 33. [Google Scholar]
  8. Winthrop KL, Proano R, Oliva O, Arana B, Mendoza C, Dominguez A, Amann J, Punkosdy G, Blanco C, Sauerbrey M, Richards F, , 2006. The reliability of anterior segment lesions as indicators of onchocercal eye disease in Guatemala. Am J Trop Med Hyg 75: 10581062. [Google Scholar]
  9. Banic DM, Calvão-Brito RHS, Marchon-Silva V, Schuertez JC, Pinheiro LR, Alves MC, Têva A, Maia-Herzog M, , 2009. Impact of 3 years ivermectin treatment on onchocerciasis in Yanomami communities in the Brazilian Amazon. Acta Trop 112: 125130.[Crossref] [Google Scholar]
  10. Pearlman E, Hall LR, , 1999. Pathogenesis of onchocercal keratitis (river blindness). Clin Microbiol Rev 3: 445453. [Google Scholar]
  11. Soboslay PT, Geiger SM, Weiss N, Banla M, Lauder CG, Dreweck CM, , 1997. Regulatory effects of Th1-type and Th2-type cytokines on parasitic specific celular responsiveness in Onchocerca volvulus infected humans and exposed endemic controls. Immunology 90: 592599.[Crossref] [Google Scholar]
  12. Potter AW, , 1998. Setting up an eye service in rural Africa. Br J Ophthalmol 82: 1451.[Crossref] [Google Scholar]
  13. Amaral WO, Teixeira RM, Alencar LM, Cronemberger S, Calixto N, , 2006. Espessura central e periférica da córnea: influência na medida da pressão intra-ocular pelo Tonopen. Arq Bras Oftalmol 69: 4145 [online].[Crossref] [Google Scholar]
  14. Shiose Y, , 1984. The aging effect on intraocular pressure in an apparently normal population. Arch Ophthalmol 102: 883887.[Crossref] [Google Scholar]
  15. Stone EM, Fingert JH, Alward WL, Nguyen TD, Polansky JR, Sunden SL, Nishimura D, Clark AF, Nystuen A, Nichols BE, Mackey DA, Ritch R, Kalenak JW, Craven ER, Sheffield VC, , 1997. Identification of a gene that causes primary open angle glaucoma. Science 275: 668670.[Crossref] [Google Scholar]

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  • Received : 17 Jun 2013
  • Accepted : 05 Aug 2013
  • Published online : 08 Jan 2014

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