Volume 89, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



The clinical and radiological features of pulmonary melioidosis can mimic tuberculosis. We prospectively evaluated 118 patients with suspected pulmonary tuberculosis who were acid-fast bacilli (AFB) smear negative at Udon Thani Hospital, northeast Thailand. Culture of residual sputum from AFB testing was positive for in three patients (2.5%; 95% confidence interval [CI] 0.5–7.3%). We propose that in melioidosis-endemic areas, residual sputum from AFB testing should be routinely cultured for .

[open-access] This is an Open Access article distributed under the terms of the American Society of Tropical Medicine and Hygiene's Re-use License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.


Article metrics loading...

The graphs shown below represent data from March 2017
Loading full text...

Full text loading...



  1. Wiersinga WJ, Currie BJ, Peacock SJ, 2012. Melioidosis. N Engl J Med 367: 10351044.[Crossref]
    [Google Scholar]
  2. Limmathurotsakul D, Wongratanacheewin S, Teerawattanasook N, Wongsuvan G, Chaisuksant S, Chetchotisakd P, Chaowagul W, Day NP, Peacock SJ, 2010. Increasing incidence of human melioidosis in northeast Thailand. Am J Trop Med Hyg 82: 11131117.[Crossref]
    [Google Scholar]
  3. Currie BJ, Ward L, Cheng AC, 2010. The epidemiology and clinical spectrum of melioidosis: 540 cases from the 20 year Darwin prospective study. PLoS Negl Trop Dis 4: e900.[Crossref]
    [Google Scholar]
  4. White NJ, Dance DA, Chaowagul W, Wattanagoon Y, Wuthiekanun V, Pitakwatchara N, 1989. Halving of mortality of severe melioidosis by ceftazidime. Lancet 2: 697701.[Crossref]
    [Google Scholar]
  5. Currie BJ, 2003. Melioidosis: an important cause of pneumonia in residents of and travellers returned from endemic regions. Eur Respir J 22: 542550.[Crossref]
    [Google Scholar]
  6. Turner MO, Lee VT, FitzGerald JM, 1994. Melioidosis in a diabetic sailor. Chest 106: 952954.[Crossref]
    [Google Scholar]
  7. Vidyalakshmi K, Chakrapani M, Shrikala B, Damodar S, Lipika S, Vishal S, 2008. Tuberculosis mimicked by melioidosis. Int J Tuberc Lung Dis 12: 12091215.
    [Google Scholar]
  8. Overtoom R, Khieu V, Hem S, Cavailler P, Te V, Chan S, Lau P, Guillard B, Vong S, 2008. A first report of pulmonary melioidosis in Cambodia. Trans R Soc Trop Med Hyg 102 (Suppl 1): S21S25.[Crossref]
    [Google Scholar]
  9. National Health Security Office (NSHO), Thailand, 2012. Submission form for Mycobacterium tuberculosis culture and drug susceptibility test (NHSOLABTB05). Document in Thai language. Available at: http://www.stoptbthailand.org. Accessed March 30, 2013.
  10. Walsh AL, Wuthiekanun V, 1996. The laboratory diagnosis of melioidosis. Br J Biomed Sci 53: 249253.
    [Google Scholar]
  11. Peacock SJ, Chieng G, Cheng AC, Dance DA, Amornchai P, Wongsuvan G, Teerawattanasook N, Chierakul W, Day NP, Wuthiekanun V, 2005. Comparison of Ashdown's medium, Burkholderia cepacia medium, and Burkholderia pseudomallei selective agar for clinical isolation of Burkholderia pseudomallei . J Clin Microbiol 43: 53595361.[Crossref]
    [Google Scholar]
  12. Warner JM, Pelowa DB, Currie BJ, 2010. Melioidosis–an uncommon but also under-recognized cause of pneumonia in Papua New Guinea. P N G Med J 53: 176179.
    [Google Scholar]
  13. Limmathurotsakul D, Jamsen K, Arayawichanont A, Simpson JA, White LJ, Lee SJ, Wuthiekanun V, Chantratita N, Cheng A, Day NP, Verzilli C, Peacock SJ, 2010. Defining the true sensitivity of culture for the diagnosis of melioidosis using Bayesian latent class models. PLoS ONE 5: e12485.[Crossref]
    [Google Scholar]

Data & Media loading...

  • Received : 23 May 2013
  • Accepted : 09 Aug 2013
  • Published online : 06 Nov 2013
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error