Volume 89, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Expanded malaria control in Kenya since the early 2000s has resulted in marked reduction in hospital admissions for malaria; however, no studies have reported changes in malaria infection rates in the same population over this period. Randomly selected archived blood samples from four cohorts of pregnant women and their children from 1996 to 2010 in Kwale District, Coast Province, Kenya, were examined for (), , , and by quantitative polymerase chain reaction (PCR) and microscopy. Maternal delivery prevalence by PCR declined from 40% in 2000–2005 to 1% in 2009–2010, concordant with increased bed net and malaria chemoprophylaxis use. Individual risk of infection in children from birth to 3 years in serial longitudinal cohort studies declined from almost 100% in 1996–1999 to 15% in 2006–2010. Declines in and infections rates were also observed. These results show a profound reduction in malaria transmission in coastal Kenya.


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  • Received : 08 May 2013
  • Accepted : 14 Aug 2013
  • Published online : 04 Dec 2013

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