1921
Volume 89, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

Tungiasis (sand flea disease) is a neglected tropical disease. Heavy infestation results in mutilation of the feet and difficulty in walking. We identified eight individuals with extremely severe tungiasis in rural Madagascar. To prevent reinfestation, four individuals received solid shoes and four received a daily application of an herbal repellent effective against . Over a period of 10 weeks the feet were examined and the severity of tungiasis-associated morbidity was measured. Within this period, the severity score for acute tungiasis decreased 41% in the shoe group and 89% in the repellent group. The four major inflammation-related symptoms disappeared in the four patients of the repellent group, but only in two patients of the shoe group. Those observations indicate that cases with extremely severe tungiasis, associated morbidity almost totally disappears within 10 weeks if the feet are protected by a repellent. Wearing shoes reduced acute morbidity only marginally.

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2013-11-06
2017-09-22
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References

  1. Heukelbach J, Oliveira F, Hesse G, Feldmeier H, , 2001. Tungiasis: a neglected health problem of poor communities. Trop Med Int Health 6: 267272.[Crossref]
  2. Feldmeier H, Heukelbach J, , 2009. Epidermal parasitic skin diseases: a neglected category of poverty-associated plagues. Bull World Health Organ 87: 152159.[Crossref]
  3. Feldmeier H, Eisele M, Heukelbach J, Saboia Moura RC, , 2003. Severe tungiasis in underprivileged communities: case series from Brazil. Emerg Infect Dis 9: 949955.[Crossref]
  4. Ade-Serrano MA, Chuks Ejezie G, , 1981. Prevalence of tungiasis in Oto-Ijanikin village, Badagry, Lagos State, Nigeria. Ann Trop Med Parasitol 75: 471472.[Crossref]
  5. Ariza L, Seidenschwang M, Buckendahl J, Gomide M, Feldmeier H, Heukelbach J, , 2007. Tungiasis: a neglected disease causing severe morbidity in a shantytown in Fortaleza, State of Ceará. Rev Soc Bras Med Trop 40: 6367.[Crossref]
  6. de Carvalho RW, De Almeida AB, Barbosa-Silva SC, Amorim M, Ribeiro PC, Serra-Freire N, , 2003. The patterns o tungiasis in Araruama township, State of Rio de Janeiro, Brazil. Mem Inst Oswaldo Cruz 96: 3136.
  7. Muehlen M, Feldmeier H, Wilcke T, Winter B, Heukelbach J, , 2006. Identifying risk factor for tungiasis and heavy infestation in a resource-poor community in northeast Brazil. Trans R Soc Trop Med Hyg 100: 371380.[Crossref]
  8. Ratovonjato J, Randriambelosoa J, Robert V, , 2008. Tunga penetrans (Insecta, Siphonaptera, Tungidae) à Madagascar: une nuisance négligée. Revue Médicine Véterinaire 11: 551556.
  9. Wilcke T, Heukelbach J, Moura RSC, Kerr-Pontes LRS, Feldmeier H, , 2002. High prevalence of tungiasis in a poor neighborhood in Fortaleza, northeast Brazil. Acta Trop 83: 255258.[Crossref]
  10. Heukelbach J, Costa AM, Wilcke T, Mencke N, Feldmeier H, , 2003. The animal reservoir of Tunga penetrans in severely affected communities in Northeast Brazil. Med Vet Entomol 18: 329335.[Crossref]
  11. Heukelbach J, Ugbomoiko US, , 2007. Tungiasis in the past and present: a dire need for intervention. Nigerian J Parasitol 28: 15.[Crossref]
  12. Heukelbach J, Wilcke T, Eisele M, Feldmeier H, , 2002. Ectopic localization of tungiasis. Am J Trop Med Hyg 67: 216.
  13. Muehlen M, Heukelbach J, Wilcke T, Winter B, Mehlhorn H, Feldmeier H, , 2003. Investigations on the biology, epidemiology, pathology and control of Tunga penetrans in Brazil: II. Prevalence, parasite load and topographic distribution of lesions in the population of a traditional fishing village. Parasitol Res 90: 449455.[Crossref]
  14. Heukelbach J, Franck S, Feldmeier H, , 2005. Therapy of tungiasis: a double-blinded randomized controlled trial with oral ivermectin. Mem Inst Oswaldo Cruz 99: 873876.[Crossref]
  15. Feldmeier H, Sentongo E, Krantz I, , 2012. Tungiasis (sand flea disease): a parasitic disease with intriguing challenges for public health. Eur J Clin Microbiol Infect Dis 32: 1926.[Crossref]
  16. Thielecke M, Raharimanga V, Rogier C, Randriamanantena H, Stauss-Grabo M, Richard V, Feldmeier H, , 2013. Prevention of tungiasis and tungiasis-associated morbidity: a randomized, controlled field study in rural Madagascar. PLoS Negl Trop Dis 7: e2426.[Crossref]
  17. Buckendahl J, Heukelbach J, Ariza L, Kehr JD, Seidenschwang M, Feldmeier H, , 2010. Control of tungiasis through intermittent application of a plant-based repellent: an intervention study in a resource-poor community in Brazil. PLoS Negl Trop Dis 4: e879. doi:10.1371/journal.pntd.0000879.[Crossref]
  18. Feldmeier H, Kehr JD, Heukelbach J, , 2006. A plant-based repellent protects against Tunga penetrans infestation and sand flea disease. Acta Trop 99: 126136.[Crossref]
  19. Schwalfenberg S, Witt LH, Kehr JD, Feldmeier H, , 2004. Prevention of tungiasis using a biological repellent: a small case series. Ann Trop Med Parasitol 98: 8994.[Crossref]
  20. Kehr JD, Heukelbach J, Mehlhorn H, Feldmeier H, , 2007. Morbidity assessment in sand flea disease (tungiasis). Parasitol Res 100: 413421.[Crossref]
  21. Joyeux CH, Sicé A, , 1937. Précis de Médecine Coloniale. Paris: Masson et Cte, 441.
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Supplementary Data

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  • Received : 07 May 2013
  • Accepted : 15 Aug 2013

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