Volume 90, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Q fever is an emergent disease in French Guiana. We compared the incidence clinical and serologic profiles between patients from Cayenne, French Guiana and Marseille in metropolitan France during a four-year period. The annual incidence of diagnosed acute Q fever was significantly higher in Cayenne (17.5/100,000) than in Marseille (1.9/100,000) ( = 0.0004), but not the annual incidence of endocarditis (1.29 versus 0.34/100,000). Most patients had fever (97%) and pneumonia (83%) in Cayenne versus 81% and 8% in Marseille ( < 0.0001 and < 0.0001, respectively) but transaminitis was more common in patients from Marseille (54% versus 32%; < 0.0001). The proportion of patients with cardiovascular infections was significantly lower in Cayenne (7%) than in Marseille (17%) ( = 0.017), although they showed a stronger immune response with higher levels of phase I IgG ( = 0.024). The differing epidemiology, clinical, and serologic responses of patients from Cayenne and Marseille suggest a different source of infection and a different strain of .


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  • Received : 27 Mar 2013
  • Accepted : 14 Apr 2013
  • Published online : 07 May 2014

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