Volume 89, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



spp. are saprophytic bacteria that are part of the marine microflora in warm climates and are rarely pathogenic. However, spp. infections are being increasingly reported, and there has been no comprehensive review of the literature describing these infections. This article reports 16 cases of spp. infections in Martinique since 1997 and reviews another 239 cases reported in the literature since 1973. Patients experienced soft tissue infections, ear infection, or abdominal and biliary tract infections. A skin or mucosal portal of entry was found for 53% of the patients and exposure to the marine environment was reported for 44%; 79% of patients had an underlying condition. Bacteriema were frequent (28%). Most (87%) patients recovered, although ear infections can become chronic. Death occurred in 13% of the patients. Most spp. isolates are susceptible to cefotaxime (95%), piperacillin and tazobactam (98%), gentamicin (99%), and ciprofloxacin (94%).


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  1. Vogel BF, Jorgensen K, Christensen H, Olsen JE, Gram L, , 1997. Differentiation of Shewanella putrefaciens and Shewanella alga on the basis of whole-cell protein profiles, ribotyping, phenotypic characterization, and 16S rRNA gene sequence analysis. Appl Environ Microbiol 63: 21892199. [Google Scholar]
  2. Khashe S, Janda JM, , 1998. Biochemical and pathogenic properties of Shewanella alga and Shewanella putrefaciens . J Clin Microbiol 36: 783787. [Google Scholar]
  3. Gram L, Bundvad A, Melchiorsen J, Johansen C, Fonnesbech Vogel B, , 1999. Occurrence of Shewanella algae in Danish coastal water and effects of water temperature and culture conditions on its survival. Appl Environ Microbiol 65: 38963900. [Google Scholar]
  4. Derby H, Hammer B, , 1931. Bacteriology of butter. Part IV. Bacteriological studies on surface tainted butter. Iowa Agric Exp Stn Res Bull 145: 389416. [Google Scholar]
  5. Holt HM, Gahrn-Hansen B, Bruun B, , 2005. Shewanella algae and Shewanella putrefaciens: clinical and microbiological characteristics. Clin Microbiol Infect 11: 347352.[Crossref] [Google Scholar]
  6. Kueh CS, Kutarski P, Brunton M, , 1992. Contaminated marine wounds: the risk of acquiring acute bacterial infection from marine recreational beaches. J Appl Bacteriol 73: 412420.[Crossref] [Google Scholar]
  7. Tsai MS, You HL, Tang YF, Liu JW, , 2008. Shewanella soft tissue infection: case report and literature review. Int J Infect Dis 12: e119e124.[Crossref] [Google Scholar]
  8. Oh HS, Kum KA, Kim EC, Lee HJ, Choe KW, Oh MD, , 2008. Outbreak of Shewanella algae and Shewanella putrefaciens infections caused by a shared measuring cup in a general surgery unit in Korea. Infect Control Hosp Epidemiol 29: 742748.[Crossref] [Google Scholar]
  9. von Graevenitz A, Simon G, , 1970. Potentially pathogenic, nonfermentative, H2S-producing gram-negative rod (1 b). Appl Microbiol 19: 176. [Google Scholar]
  10. Gilardi GL, , 1972. Infrequently encountered Pseudomonas species causing infection in humans. Ann Intern Med 77: 211215.[Crossref] [Google Scholar]
  11. Riley PS, Tatum HW, Weaver RE, , 1972. Pseudomonas putrefaciens isolates from clinical specimens. Appl Microbiol 24: 798800. [Google Scholar]
  12. Holmes B, Lapage SP, Malnick H, , 1975. Strains of Pseudomonas putrefaciens from clinical material. J Clin Pathol 28: 149155.[Crossref] [Google Scholar]
  13. Rosenthal SL, Zuger JH, Apollo E, , 1975. Respiratory colonization with Pseudomonas putrefaciens after near-drowning in salt water. Am J Clin Pathol 64: 382384.[Crossref] [Google Scholar]
  14. Debois J, Degreef H, Vandepitte J, Spaepen J, , 1975. Pseudomonas putrefaciens as a cause of infection in humans. J Clin Pathol 28: 993996.[Crossref] [Google Scholar]
  15. Thong ML, , 1976. Pseudomonas putrefaciens from clinical material. Southeast Asian J Trop Med Public Health 7: 363366. [Google Scholar]
  16. Appelbaum PC, Bowen AJ, , 1978. Opportunistic infection of chronic skin ulcers with Pseudomonas putrefaciens . Br J Dermatol 98: 229231.[Crossref] [Google Scholar]
  17. Vandepitte J, Debois J, , 1978. Pseudomonas putrefaciens as a cause of bacteremia in humans. J Clin Microbiol 7: 7072. [Google Scholar]
  18. Schmidt U, Kapila R, Kaminski Z, Louria D, , 1979. Pseudomonas putrefaciens as a cause of septicemia in humans. J Clin Microbiol 10: 385387. [Google Scholar]
  19. Eschete ML, Williams F, West BC, , 1980. Pseudomonas putrefaciens and group A beta-hemolytic Streptococcus septicemia . Arch Intern Med 140: 15331534.[Crossref] [Google Scholar]
  20. Pope TL, Teague WG, Kossack R, Bray ST, Flannery DB, , 1982. Pseudomonas sacroiliac osteomyelitis: diagnosis by gallium citrate Ga 67 scan. Am J Dis Child 136: 649650. [Google Scholar]
  21. Laudat P, Audurier A, Loulergue F, Legros B, Lapierre F, , 1983. Pseudomonas putrefaciens meningitis. J Infect 7: 281283.[Crossref] [Google Scholar]
  22. Marne C, Pallares R, Sitges-Serra A, , 1983. Isolation of Pseudomonas putrefaciens in intra-abdominal sepsis. J Clin Microbiol 17: 11731174. [Google Scholar]
  23. Kim JH, Cooper RA, Welty-Wolf KE, Harrell LJ, Zwadyk P, Klotman ME, , 1989. Pseudomonas putrefaciens bacteremia. Rev Infect Dis 11: 97104.[Crossref] [Google Scholar]
  24. Heller HM, Tortora G, Burger H, , 1990. Pseudomonas putrefaciens bacteremia associated with shellfish contact. Am J Med 88: 8586.[Crossref] [Google Scholar]
  25. Chen SC, Lawrence RH, Packham DR, Sorrell TC, , 1991. Cellulitis due to Pseudomonas putrefaciens: possible production of exotoxins. Rev Infect Dis 13: 642643.[Crossref] [Google Scholar]
  26. Roger SD, Chen SC, Lawrence S, Sorrell TC, , 1991. Pseudomonas putrefaciens bacteraemia in a peritoneal dialysis patient. Nephrol Dial Transplant 6: 73.[Crossref] [Google Scholar]
  27. Dan M, Gutman R, Biro A, , 1992. Peritonitis caused by Pseudomonas putrefaciens in patients undergoing continuous ambulatory peritoneal dialysis. Clin Infect Dis 14: 359360.[Crossref] [Google Scholar]
  28. Brink AJ, van Straten A, van Rensburg AJ, , 1995. Shewanella (Pseudomonas) putrefaciens bacteremia. Clin Infect Dis 20: 13271332.[Crossref] [Google Scholar]
  29. Dominguez H, Vogel BF, Gram L, Hoffmann S, Schaebel S, , 1996. Shewanella alga bacteremia in two patients with lower leg ulcers. Clin Infect Dis 22: 10361039.[Crossref] [Google Scholar]
  30. Butt AA, Figueroa J, Martin DH, , 1997. Ocular infection caused by three unusual marine organisms. Clin Infect Dis 24: 740.[Crossref] [Google Scholar]
  31. Chen YS, Liu YC, Yen MY, Wang JH, Wang JH, Wann SR, Cheng DL, , 1997. Skin and soft-tissue manifestations of Shewanella putrefaciens infection. Clin Infect Dis 25: 225229.[Crossref] [Google Scholar]
  32. Holt HM, Sogaard P, Gahrn-Hansen B, , 1997. Ear infections with Shewanella alga: a bacteriologic, clinical and epidemiologic study of 67 cases. Clin Microbiol Infect 3: 329334.[Crossref] [Google Scholar]
  33. Yohe S, Fishbain JT, Andrews M, , 1997. Shewanella putrefaciens abscess of the lower extremity. J Clin Microbiol 35: 3363. [Google Scholar]
  34. Dhawan B, Chaudhry R, Mishra BM, Agarwal R, , 1998. Isolation of Shewanella putrefaciens from a rheumatic heart disease patient with infective endocarditis. J Clin Microbiol 36: 2394. [Google Scholar]
  35. Levy PY, Tessier JL, , 1998. Arthritis due to Shewanella putrefaciens . Clin Infect Dis 26: 536.[Crossref] [Google Scholar]
  36. Papanaoum K, Marshmann G, Gordon LA, Lumb R, Gordon DL, , 1998. Concurrent infection due to Shewanella putrefaciens and Mycobacterium marinum acquired at the beach. Australas J Dermatol 39: 9295.[Crossref] [Google Scholar]
  37. Bhandari S, Pan TL, Horvath J, Tiller D, , 2000. CAPD, swimming in Shewanella . Nephrol Dial Transplant 15: 14841485.[Crossref] [Google Scholar]
  38. Leong J, Mirkazemi M, Kimble F, , 2000. Shewanella putrefaciens hand infection. Aust N Z J Surg 70: 816817.[Crossref] [Google Scholar]
  39. Liao WY, Liaw YS, Wang HC, Chen KY, Luh KT, Yang PC, , 2000. Bacteriology of infected cavitating lung tumor. Am J Respir Crit Care Med 161: 17501753.[Crossref] [Google Scholar]
  40. Paccalin M, Grollier G, le Moal G, Rayeh F, Camiade C, , 2001. Rupture of a primary aortic aneurysm infected with Shewanella alga . Scand J Infect Dis 33: 774775.[Crossref] [Google Scholar]
  41. Krsnik I, Arribalzaga K, Romanyk J, , 2002. Shewanella alga bacteremia and associated cellulitis in a patient with multiple myeloma. Haematologia (Budap) 32: 7980.[Crossref] [Google Scholar]
  42. Pagani L, Lang A, Vedovelli C, Moling O, Rimenti G, Pristera R, Mian P, , 2003. Soft tissue infection and bacteremia caused by Shewanella putrefaciens . J Clin Microbiol 41: 22402241.[Crossref] [Google Scholar]
  43. Bulut C, Ertem GT, Gokcek C, Tulek N, Bayar MA, Karakoc E, , 2004. A rare cause of wound infection: Shewanella putrefaciens . Scand J Infect Dis 36: 692694.[Crossref] [Google Scholar]
  44. Clement LF, Gallet C, Perron J, Lesueur A, , 2004. Infectious cellulitis and Shewanella alga septicemia in an immunocompetent patient [in French]. Ann Dermatol Venereol 131: 10951097.[Crossref] [Google Scholar]
  45. Jorens PG, Goovaerts K, Ieven M, , 2004. Shewanella putrefaciens isolated in a case of ventilator-associated pneumonia. Respiration 71: 199201.[Crossref] [Google Scholar]
  46. Suzuk S, Yetener V, Ergungor F, Balaban N, , 2004. Cerebellar abscess caused by Shewanella putrefaciens . Scand J Infect Dis 36: 621622.[Crossref] [Google Scholar]
  47. Botelho-Nevers E, Gouriet F, Rovery C, Paris P, Roux V, Raoult D, Brouqui P, , 2005. First case of osteomyelitis due to Shewanella algae . J Clin Microbiol 43: 53885390.[Crossref] [Google Scholar]
  48. Tsai TH, You HY, , 2006. Necrotizing fasciitis caused by Shewanella putrefaciens in a uremic patient. J Microbiol Immunol Infect 39: 516518. [Google Scholar]
  49. Park HJ, Tuli SS, Downer DM, Gohari AR, Shah M, , 2007. Shewanella putrefaciens keratitis in the lamellar bed 6 years after LASIK. J Refract Surg 23: 830832. [Google Scholar]
  50. Grocholski AS, Delage M, Samimi M, Maruani A, , 2009. Acute dermohypodermitis of the right leg (S. putrefaciens) after sea bathing [in French]. Ann Dermatol Venereol 136: 5960.[Crossref] [Google Scholar]
  51. Bhalerao DS, Kinikar AG, Roushani SB, Franklin VX, , 2010. Shewanelia putrefaciens: a rare microbial agent associated with a non-healing ulcer in a leprosy patient. Indian J Lepr 82: 205207. [Google Scholar]
  52. Gressier M, Mbayo D, Deramond H, Grados F, Eb F, Canarelli B, , 2010. First case of human spondylodiscitis due to Shewanella algae. Int J Infect Dis 14 (Suppl 3): e261e264.[Crossref] [Google Scholar]
  53. Sharma KK, Kalawat U, , 2010. Emerging infections: Shewanella - a series of five cases. J Lab Physicians 2: 6165.[Crossref] [Google Scholar]
  54. Tucker C, Baroso G, Tan P, , 2010. Ventilator-associated pneumonia due to Shewanella putrefaciens . Am J Health Syst Pharm 67: 10071009.[Crossref] [Google Scholar]
  55. Goyal R, Kaur N, Thakur R, , 2011. Human soft tissue infection by the emerging pathogen Shewanella algae . J Infect Dev Ctries 5: 310312.[Crossref] [Google Scholar]
  56. Finkelstein R, Oren I, , 2011. Soft tissue infections caused by marine bacterial pathogens: epidemiology, diagnosis, and management. Curr Infect Dis Rep 13: 470477.[Crossref] [Google Scholar]
  57. Heritier C, Poirel L, Nordmann P, , 2004. Genetic and biochemical characterization of a chromosome-encoded carbapenem-hydrolyzing ambler class D beta-lactamase from Shewanella algae . Antimicrob Agents Chemother 48: 16701675.[Crossref] [Google Scholar]

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  • Received : 27 Jan 2013
  • Accepted : 17 Apr 2013
  • Published online : 10 Jul 2013

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