Volume 89, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



A cross-sectional, community-based study was performed in 2012 with 428 residents of periurban shantytowns in Lima, Peru to study risk factors for and changes in latent tuberculosis infection in age-stratified groups compared with our data from the same region in 1990 ( = 219) and 2005 ( = 103). Tuberculin skin test positivity in these communities was highly prevalent at 52% overall, increased with age ( < 0.01) and was similar to 2005 (53%) and 1990 (48%). From 1990 to 2012, the prevalence of tuberculin positivity decreased in 5–14 and 15–24 year old groups (to 17% and 34%, respectively, both < 0.05). However, this may be explained by cessation of Bacille Calmette-Guérin revaccination during this period, because Bacille Calmette-Guérin revaccination doubled tuberculin positivity. Over the same 22-year period, tuberculin positivity in the ≥ 25 year old group remained high (71%, = 0.3), suggesting that prevalent latent tuberculosis infection persists in the adult population despite improving medical care and socioeconomic development in this region.


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  • Received : 03 Jan 2013
  • Accepted : 20 Jun 2013
  • Published online : 04 Sep 2013

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