1921
Volume 89, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

Despite having the highest burden in the world, molecular epidemiological data from Papua New Guinea (PNG) for this parasite remain limited. To investigate the molecular epidemiology of in PNG, 574 isolates collected from four catchment sites in East Sepik ( = 1) and Madang ( = 3) Provinces were genotyped using the markers MS16 and F3. Genetic diversity and prevalence of was determined for all sites. Despite a infection prevalence in the East Sepik (15%) catchments less than one-half the prevalence of the Madang catchments (27–35%), genetic diversity was similarly high in all populations ( = 0.77–0.98). High genetic diversity, despite a marked difference in infection prevalence, suggests a large reservoir of diversity in populations of PNG. Significant reductions in transmission intensity may, therefore, be required to reduce the diversity of parasite populations in highly endemic countries such as PNG.

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  • Received : 20 Dec 2012
  • Accepted : 19 Mar 2013

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