Volume 88, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



We investigated the humoral immune response against different species of in serum samples from small rodents collected in two areas of a silent focus for Brazilian spotted fever in the eastern region of Minas Gerais State, Brazil. Sera samples were analyzed by indirect immunofluorescence assay using antigens from species of the spotted fever, ancestral, and transition groups. Titers ≥ 1:64 were considered positive. In Santa Cruz do Escalvado, 94% (30 of 32) of the samples collected from , 22% (5 of 23) from , and 80% (4 of 5) from sp., reacted by indirect immunofluorescence assay with antigens of the spotted fever group. In the municipality of Pingo D'Água, 84% (26 of 31) of the samples collected from , 86% (6 of 7) of the samples from , 86% (6 of 7) from , and 100% (1 of 1) from sp. contained antibodies that reacted with rickettsial antigens of the spotted fever group. These results demonstrated the previous exposure of small rodents to spotted fever group , suggesting the participation of these animals in the natural history of these rickettsiae in this region.


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  • Received : 01 Oct 2012
  • Accepted : 24 Dec 2012
  • Published online : 01 May 2013

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