1921
Volume 88, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

A four-year longitudinal study of the structure of sylvatic transmission cycles of , reservoir host competence and parasite discrete typing units was conducted in a disturbed rural area of the humid Chaco in Argentina. Among 190 mammals examined by xenodiagnosis and polymerase chain reaction amplification, the composite prevalence of infection was substantially higher in armadillos (57.7%) and opossums (38.1%) than in (20.0%), (12.5%), and (6.3%) armadillos. was detected for the first time in small opossums and in two unidentified small rodents. Infection was spatially aggregated only in armadillos. All were infected with I and all armadillo species were infected with III, implying two distinct sylvatic cycles with no inputs from the domestic cycle. armadillos and opossums were much more infectious to vectors than other armadillos, small opossums, or rodents.

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2017-11-21
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References

  1. Schofield CJ, Jannin J, Salvatella R, , 2006. The future of Chagas disease control. Trends Parasitol 22: 583588.[Crossref]
  2. World Health Organization, 2002. Control of Chagas Disease: Second Report of the WHO Expert Committee. Geneva: World Health Organization.
  3. Zingales B, Andrade SG, Briones MR, Campbell DA, Chiari E, Fernandes O, Guhl F, Lages-Silva E, Macedo AM, Machado CR, Miles MA, Romanha AJ, Sturm NR, Tibayrenc M, Schijman AG, , 2009. A new consensus for Trypanosoma cruzi intraspecific nomenclature: second revision meeting recommends TcI to TcVI. Mem Inst Oswaldo Cruz 104: 10511054.[Crossref]
  4. Barnabe C, Brisse S, Tibayrenc M, , 2000. Population structure and genetic typing of Trypanosoma cruzi, the agent of Chagas disease: a multilocus enzyme electrophoresis approach. Parasitology 120: 513526.[Crossref]
  5. Miles MA, Feliciangeli MD, de Arias AR, , 2003. American trypanosomiasis (Chagas' disease) and the role of molecular epidemiology in guiding control strategies. BMJ 326: 14441448.[Crossref]
  6. Lewis MD, Ma J, Yeo M, Carrasco HJ, Llewellyn MS, Miles MA, , 2009. Genotyping of Trypanosoma cruzi: systematic selection of assays allowing rapid and accurate discrimination of all known lineages. Am J Trop Med Hyg 81: 10411049.[Crossref]
  7. Yeo M, Acosta N, Llewellyn M, Sanchez H, Adamson S, Miles GA, Lopez E, Gonzalez N, Patterson JS, Gaunt MW, de Arias AR, Miles MA, , 2005. Origins of Chagas disease: Didelphis species are natural hosts of Trypanosoma cruzi I and armadillos hosts of Trypanosoma cruzi II, including hybrids. Int J Parasitol 35: 225233.[Crossref]
  8. Noireau F, Diosque P, Jansen AM, , 2009. Trypanosoma cruzi: adaptation to its vectors and its hosts. Vet Res 40: 26.[Crossref]
  9. Llewellyn MS, Lewis MD, Acosta N, Yeo M, Carrasco HJ, Segovia M, Vargas J, Torrico F, Miles MA, Gaunt MW, , 2009. Trypanosoma cruzi IIc: phylogenetic and phylogeographic insights from sequence and microsatellite analysis and potential impact on emergent Chagas disease. PLoS Negl Trop Dis 3: e510.[Crossref]
  10. The Nature Conservancy (TNC), Fundación Vida Silvestre Argentina (FVSA), Fundación para el Desarrollo Sustentable del Chaco (DeSdel Chaco) y Wildife Conservation Society Bolivia (WCS), 2005. Evaluación Ecorregional del Gran Chaco Americano/Gran Chaco Americano Ecoregional Assessment. Buenos Aires. Fundación Vida Silvestre Argentina. Available at: http://www.vidasilvestre.org.ar/sala_redaccion/opublicaciones/publicaciones_bosques_y_selvas/?2980/Evaluacin-Ecorregional-del-Gran-Chaco-Americano. Accessed January 15, 2012.
  11. Gürtler RE, Kitron U, Cecere MC, Segura EL, Cohen JE, , 2007. Sustainable vector control and management of Chagas disease in the Gran Chaco, Argentina. Proc Natl Acad Sci USA 104: 1619416199.[Crossref]
  12. Bucher EH, Huszar PC, , 1999. Sustainable management of the Gran Chaco of South America. J Environ Manage 57: 99108.[Crossref]
  13. Mazza S, Romaña C, Schurman K, , 1930. New observations on the spontaneous infection of armadillos of the country by Trypanosoma cruzi . Prensa Med Argent 3: 320.
  14. Carcavallo RU, Martínez A, , 1968. Entomoepidemiology of the Argentine Republic. Investigaciones Científicas de las Fuerzas Armadas Argentinas 1: 7692.
  15. Barretto MP, Carcavallo RU, Rabinovich JE, Tonn RJ, , 1985. Reservoirs of Trypanosoma (Schizotrypanum) cruzi (Chagas 1909). , eds. Biological and ecological factors in Chagas disease. Buenos Aires, Argentina: Organización Panamericana de la Salud/Servicio Nacional de Chagas, 275288.
  16. Wisnivesky-Colli C, Schweigmann NJ, Alberti A, Pietrokovsky SM, Conti O, Montoya S, Riarte A, Rivas C, , 1992. Sylvatic American trypanosomiasis in Argentina. Trypanosoma cruzi infection in mammals from the Chaco forest in Santiago del Estero. Trans R Soc Trop Med Hyg 86: 3841.[Crossref]
  17. Schweigmann NJ, Pietrokovsky S, Bottazzi V, Conti O, Bujas MA, Wisnivesky-Colli C, , 1999. Prevalence of Trypanosoma cruzi infection in opossum (Didelphis albiventris) in Santiago del Estero, Argentina. Rev Panam Salud Publica 6: 371377.[Crossref]
  18. Diosque P, Padilla AM, Cimino RO, Cardozo RM, Negrette OS, Marco JD, Zacca R, Meza C, Juarez A, Rojo H, Rey R, Corrales RM, Nasser JR, Basombrio MA, , 2004. Chagas disease in rural areas of Chaco Province, Argentina: epidemiologic survey in humans, reservoirs, and vectors. Am J Trop Med Hyg 71: 590593.
  19. Ceballos LA, Cardinal MV, Vazquez-Prokopec GM, Lauricella MA, Orozco MM, Cortinas R, Schijman AG, Levin MJ, Kitron U, Gürtler RE, , 2006. Long-term reduction of Trypanosoma cruzi infection in sylvatic mammals following deforestation and sustained vector surveillance in northwestern Argentina. Acta Trop 98: 286296.[Crossref]
  20. Alvarado-Otegui JA, Ceballos LA, Orozco MM, Enriquez GF, Cardinal MV, Cura C, Schijman AG, Kitron U, Gürtler RE, , 2012. The sylvatic transmission cycle of Trypanosoma cruzi in a rural area in the humid Chaco of Argentina. Acta Trop 124: 7986.[Crossref]
  21. Daszak P, Cunningham AA, Hyatt AD, , 2000. Emerging infectious diseases of wildlife–threats to biodiversity and human health. Science 287: 443449.[Crossref]
  22. Herrera HM, Rademaker V, Abreu UG, D'Andrea PS, Jansen AM, , 2007. Variables that modulate the spatial distribution of Trypanosoma cruzi and Trypanosoma evansi in the Brazilian Pantanal. Acta Trop 102: 5562.[Crossref]
  23. Vaz VC, D'Andrea PS, Jansen AM, , 2007. Effects of habitat fragmentation on wild mammal infection by Trypanosoma cruzi . Parasitology 134: 17851793.[Crossref]
  24. Cardinal MV, Lauricella MA, Ceballos LA, Lanati L, Marcet PL, Levin MJ, Kitron U, Gürtler RE, Schijman AG, , 2008. Molecular epidemiology of domestic and sylvatic Trypanosoma cruzi infection in rural northwestern Argentina. Int J Parasitol 38: 15331543.[Crossref]
  25. Brenière SF, Aliaga C, Waleckx E, Buitrago R, Salas R, Barnabé C, Tibayrenc M, Noireau F, , 2012. Genetic characterization of Trypanosoma cruzi DTUs in wild Triatoma infestans from Bolivia: predominance of TcI. PLoS Negl Trop Dis 6: e1650.[Crossref]
  26. Gurevitz JM, Ceballos LA, Gaspe MS, Alvarado-Otegui JA, Enriquez GF, Kitron U, Gürtler RE, , 2011. Factors affecting infestation by Triatoma infestans in a rural area of the humid Chaco in Argentina: a multi-model inference approach. PLoS Negl Trop Dis 5: e1349.[Crossref]
  27. Kreeger TJ, Arnemo JM, , 2007. Handbook of Wildlife Chemical Immobilization. Vancouver, British Columbia, Canada: Sunquest.
  28. Gürtler RE, Cecere MC, Lauricella MA, Cardinal MV, Kitron U, Cohen JE, , 2007. Domestic dogs and cats as sources of Trypanosoma cruzi infection in rural northwestern Argentina. Parasitology 134: 6982.[Crossref]
  29. Burgos JM, Altcheh J, Bisio M, Duffy T, Valadares HM, Seidenstein ME, Piccinali R, Freitas JM, Levin MJ, Macchi L, Macedo AM, Freilij H, Schijman AG, , 2007. Direct molecular profiling of minicircle signatures and lineages of Trypanosoma cruzi bloodstream populations causing congenital Chagas disease. Int J Parasitol 37: 13191327.[Crossref]
  30. Wiegand T, Moloney KA, , 2004. Rings, circles, and null-models for point pattern analysis in ecology. Oikos 104: 209229.[Crossref]
  31. Maffey L, Cardinal MV, Ordóñez-Krasnowski PC, Lanati LA, Lauricella MA, Schijman AG, Gürtler RE, , 2012. Direct molecular identification of Trypanosoma cruzi discrete typing units in domestic and peridomestic Triatoma infestans and Triatoma sordida from the Argentine Chaco. Parasitology 139: 15701579.[Crossref]
  32. Cleaveland S, Dye C, , 1995. Maintenance of a microparasite infecting several host species: rabies in the Serengeti. Parasitology 111 (Suppl): S33S47.[Crossref]
  33. Zeledón R, , 1974. Epidemiology, modes of transmission and reservoir hosts of Chagas' disease. Trypanosomiasis and leishmaniasis with special reference to Chagas disease. CIBA Foundation Symposium 20 (new series): 5177.
  34. Mazza S, Romaña C, Schürmann K, , 1931. New observations on the spontaneous infection of armadillos of the country by Trypanosoma cruzi. Finding of this flagellate in Dasypus novemcinctus Lin. in the Chaco of Santa Fe. Prensa Med Argent 3: 20.
  35. Martínez FA, Guana Añasco LG, Resoagli EH, , 1983. The species of Dasypodidae as reservoirs of Chagas disease in northeastern Argentina. Gac. Vet. (Buenos Aires) 45: 376383.
  36. Bruno N, Cuéllar E, Cabrera E, Mercolli C, Resquín R, , 2000. Feeding habits of five armadillos in the Bolivian Chaco. , eds. Manejo de Fauna Silvestre en Amazonía y Latinoamérica. Asunción, Paraguay: CITES Paraguay-Fundación Moisés Bertoni, Universidad de Florida, 401441.
  37. Mazza S, Schreiber F, , 1938. Finding in the Obligado Department, Santa Fe, of another species of mustelid naturally infected by Schizotrypanum cruzi, of infected Triatoma infestans in opossum nests, of infected Triatoma platensis in parrot nests and of Psammolestes coreodes without infestation in dendrocolaptid nests. Misión de Estudios de Patología Regional Argentina. Universidad de Buenos Aires 34: 1735.
  38. Travi BL, Jaramillo C, Montoya J, Segura I, Zea A, Goncalves A, Velez ID, , 1994. Didelphis marsupialis, an important reservoir of Trypanosoma (Schizotrypanum) cruzi and Leishmania (Leishmania) chagasi in Colombia. Am J Trop Med Hyg 50: 557565.
  39. Grisard EC, Carvalho-Pinto CJ, Scholz AF, Toma HK, Schlemper BR, Jr Steindel M, , 2000. Trypanosoma cruzi infection in Didelphis marsupialis in Santa Catarina and Arvoredo Islands, southern Brazil. Mem Inst Oswaldo Cruz 95: 795800.[Crossref]
  40. Rozas M, Botto-Mahan C, Coronado X, Ortiz S, Cattan PE, Solari A, , 2005. Short report: Trypanosoma cruzi infection in wild mammals from a chagasic area of Chile. Am J Trop Med Hyg 73: 517519.
  41. Duffy T, Bisio M, Altcheh J, Burgos JM, Diez M, Levin MJ, Favaloro RR, Freilij H, Schijman AG, , 2009. Accurate real-time PCR strategy for monitoring bloodstream parasitic loads in chagas disease patients. PLoS Negl Trop Dis 3: e419.[Crossref]
  42. Gaunt M, Miles M, , 2000. The ecotopes and evolution of triatomine bugs (triatominae) and their associated trypanosomes. Mem Inst Oswaldo Cruz 95: 557565.[Crossref]
  43. Marcili A, Lima L, Valente VC, Valente SA, Batista JS, Junqueira AC, Souza AI, da Rosa JA, Campaner M, Lewis MD, Llewellyn MS, Miles MA, Teixeira MM, , 2009. Comparative phylogeography of Trypanosoma cruzi TCIIc: new hosts, association with terrestrial ecotopes, and spatial clustering. Infect Genet Evol 9: 12651274.[Crossref]
  44. Abba AM, Cassini M, Vizcaíno S, , 2007. Effects of land use on the distribution of three species of armadillos (Mammalia, Dasypodidae) in the pampas, Argentina. J Mammal 88: 502507.[Crossref]
  45. Noss A, Cuéllar E, Cuéllar R, , 2003. Hunter self-monitoring as a basis for biological research: data from the Bolivian Chaco. Mastozool Neotrop 10: 4967.
  46. Enríquez GF, Cardinal MV, Orozco MM, Lanati L, Schijman AG, Gürtler RE, , 2012. Discrete typing units of Trypanosoma cruzi identified in rural dogs and cats in the humid Argentinean Chaco. Parasitology 140: 303308.[Crossref]
  47. Chapman MD, Baggaley RC, Godfrey-Fausset PF, Malpas TJ, White G, Canese J, Miles MA, , 1984. Trypanosoma cruzi from the Paraguayan Chaco: isoenzyme profiles of strains isolated at Makthlawaiya. J Protozool 31: 482486.[Crossref]
  48. Diotaiuti L, Pereira AS, Loiola CF, Fernandes AJ, Schofield JC, Dujardin JP, Dias JC, Chiari E, , 1995. Inter-relation of sylvatic and domestic transmission of Trypanosoma cruzi in areas with and without domestic vectorial transmission in Minas Gerais, Brazil. Mem Inst Oswaldo Cruz 90: 443448.[Crossref]
  49. Noireau F, Cortez MG, Monteiro FA, Jansen AM, Torrico F, , 2005. Can wild Triatoma infestans foci in Bolivia jeopardize Chagas disease control efforts? Trends Parasitol 21: 710.[Crossref]
  50. Ceballos LA, Piccinali RV, Marcet PL, Vazquez-Prokopec GM, Cardinal MV, Schachter-Broide J, Dujardin JP, Dotson EM, Kitron U, Gürtler RE, , 2011. Hidden sylvatic foci of the main vector of Chagas disease Triatoma infestans: threats to the vector elimination campaign? PLoS Negl Trop Dis 5: e1365.[Crossref]
  51. Rolon M, Vega MC, Roman F, Gomez A, Rojas de Arias A, , 2011. First report of colonies of sylvatic Triatoma infestans (Hemiptera: Reduviidae) in the Paraguayan Chaco, using a trained dog. PLoS Negl Trop Dis 5: e1026.[Crossref]
  52. Yeo M, Lewis MD, Carrasco HJ, Acosta N, Llewellyn M, da Silva Valente SA, de Costa Valente V, de Arias AR, Miles MA, , 2007. Resolution of multiclonal infections of Trypanosoma cruzi from naturally infected triatomine bugs and from experimentally infected mice by direct plating on a sensitive solid medium. Int J Parasitol 37: 111120.[Crossref]
  53. Burgos JM, Begher SB, Freitas JM, Bisio M, Duffy T, Altcheh J, Teijeiro R, Lopez Alcoba H, Deccarlini F, Freilij H, Levin MJ, Levalle J, Macedo AM, Schijman AG, , 2005. Molecular diagnosis and typing of Trypanosoma cruzi populations and lineages in cerebral Chagas disease in a patient with AIDS. Am J Trop Med Hyg 73: 10161018.
  54. Xavier SC, Roque AL, Lima V dos S, Monteiro KJ, Otaviano JC, Ferreira da Silva LF, Jansen AM, , 2012. Lower richness of small wild mammal species and chagas disease risk. PLoS Negl Trop Dis 6: e1647.[Crossref]
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  • Received : 24 Aug 2012
  • Accepted : 09 Dec 2012

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