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Am. J. Trop. Med. Hyg., 74(4), 2006, pp. 520
Copyright © 2006 by The American Society of Tropical Medicine and Hygiene

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LETTER TO THE EDITOR


IN REPLY

Cedric Pennetier
Jean-Marc Hougard
Vincent Corbel
Institut de Recherche pour le Développement, Cotonou, Benin, E-mail: cedric.pennetier{at}ird.fr
Laboratoire de Lutte contre les Insectes Nuisibles, Institut de Recherche pour le Développement, Montpellier, France

Dear Sir:

Moss effectively published first the evidence of synergism between N,N-diethyl-m-toluamide (DEET) and hydrolytic enzyme inhibitors.1 Although we illustrated a synergy between DEET and propoxur in our study,2 the most important result was that such mixtures could replace efficiently pyrethroid insecticides, particularly in knockdown resistance areas. A mixture of reduced quantities of DEET and propoxur induced the knock down effect, mortality, and irritancy as well as deltamethrin. We agree that it would have been relevant in our discussion to cite the report by Moss because it raised relevant assumptions about the mode of action of DEET.

 

REFERENCES

  1. Moss JI, 1996. Synergism of toxicity of N,N-diethyl-m-toluamide to German cockroaches (Ortoptera: Blattelidae) by hydrolytic enzyme inhibitors. J Econ Entomol 89: 1151–1155.[ISI][Medline]
  2. Pennetier C, Corbel V, Hougard JM, 2005. Combination of a non-pyrethroid insecticide and a repellent: a new approach for controlling knockdown-resistant mosquitoes. Am J Trop Med Hyg 72: 739–744.[Abstract/Free Full Text]




This Article
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Right arrow Articles by Pennetier, C.
Right arrow Articles by Corbel, V.
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PubMed
Right arrow Articles by Pennetier, C.
Right arrow Articles by Corbel, V.

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