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The diagnosis of yellow fever was easy in those great epidemics of the prefinlayan America, when thousands of cases presented themselves in the immigrants under the well-known severe and generally fatal symptoms as described in the textbooks. The medical profession did not realize at that time that a great number of other cases completely escaped their attention, because they were so mild that they did not need a doctor's assistance.
Today we know from numerous experiences that in many infectious diseases the mild or symptomless cases are the ones that are of special epidemiological importance in connection with the propagation of the infective germs and therefore are almost more dangerous than the well marked and easily controlled severe cases. So it happens in yellow fever, which as long as it is merely endemic occurs in such a mild form that it is difficult or often impossible to make the diagnosis with certainty.
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