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Nutrition and Resistance—Susceptibility to Infection¹

An invitation to discuss nutrition in relation to resistance before a gathering of students of tropical medicine when proffered to one who has never before participated in tropical medical activities can, I think, be best explained by (1) a tolerant broad-mindedness of the program committee and (2) a recognition that the tap roots of tropical medicine run deep into the subsoil of theory which underlies infectious disease in general. Among these roots our mutual problems lie tangled among the aged, yet by no means fossilized concepts of virulence and avirulence, resistance and susceptibility. It is my thesis this afternoon that nutrition, in its relationship to these central issues, has not yet come to flower, but if we wish to see its growth, we must look to its roots as it penetrates ever deeper. This penetration can be expected to make two different kinds of contributions, the one practical and the other theoretical in its implications.

¹ From the symposium on "Nutrition in Relation to Tropical Medicine," 46th Annual Meeting of the American Society of Tropical Medicine, November 7, 1950, Savannah, Ga.

² Laboratories of the Rockefeller Institute for Medical Research, New York.