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A Study of the Concentration of Yellow Fever Virus which Will Infect Certain Species of Aedes Mosquitoes¹

1. A study was made of the concentration of virus which was necessary to infect certain species of Aedes mosquitoes with yellow fever.

2. The lowest titer at which transmission by bite occurred was 10^-3.0.

3. Half or more than half of the mosquitoes, which fed on primates circulating yellow fever virus at titers of 10^-5.0 or above, became infected after extrinsic incubation periods of at least 28 days at 28°C.

¹ The studies and observations on which this paper is based were conducted with the support in under the auspices of the Yellow Fever Research Service, which was maintained jointly by the Ministry of Education and Health of Brazil and by the International Health Division of The Rockefeller Foundation.

² Members Field Staff, International Health Division, Rockefeller Foundation, 49 West 49th St., New York 20, N. Y.