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Dengue Fever

A Clinical Report of the Galveston Epidemic of 1922

1. The 1922 epidemic of dengue in Galveston followed a plague of yellow fever mosquitoes, and subsequently spread throughout the State.

2. The disease presents a few characteristic features and should not be confused with other clinical entities.

3. The rash may vary, but is distinctive.

4. Uterine hemorrhages are common in dengue, and hemorrhages from any mucous surface may occur.

5. Recurrences are seen, and partial immunity is of short duration, probably less than four months.

6. The incubation period varies between four and fourteen days.

7. Pregnancy is not disturbed.

8. No specific treatment is known.

Received February 16, 1923.