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TPB represents the "active form", i.e. the arsenoxide of tryparsamide in a stabilized and detoxified form, combining high trypanocidal activity towards the trypanosomes in blood and lymph and CSF, with the propensity to clear up readily the trypanosome meningo-encephalitis.
TPB is without effect on tryparsamide resistant trypanosomes.
1 From the Laboratory of Ernst A. H. Friedheim, 333 West 52nd St., New York 19, N. Y.
2 In collaboration with the Sleeping Sickness Service of French West Africa.
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