AJTMH ASTMH Job Mart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am. J. Trop. Med., s1-28(4), 1948, pp. 551-554
Copyright © 1948 by American Journal of Tropical Medicine

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lewis,, J. L.
Right arrow Articles by Spicknall, C. G.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Lewis,, J. L., Jr.
Right arrow Articles by Spicknall, C. G.

Visceral Leishmaniasis (Kala-Azar)

Report of a Case1

J. L. Lewis,, Jr., M.D.2 AND Charles G. Spicknall, M.D.3

A case of visceral leishmaniasis of exogenous origin was observed at the U. S. Marine Hospital, Baltimore, Maryland. The diagnosis was definitely established by sternal biopsy. A rapid response to treatment with ethylstibamine occurred, and the patient remained well during 2 months further observation. This patient showed a response to specific therapy which was somewhat more rapid than that usually seen. More prolonged observation following treatment would have been desirable but was not feasible in this case. In the experience of Most and Lavietes (4), while the average interval to relapse following Neostibosan treatment was 5.8 weeks, they found instances of late relapse, and advise observation for 4 to 6 months after treatment. They recommend Neostibosan as the drug of choice in the treatment of the initial infection.

In this case the complement fixation test with L. donovani was positive before treatment. During convalescence, intradermal tests with L. tropica, L. donovani, and L. braziliensis were positive. While the interpretation to be placed on these tests is essentially unknown, the positive reactions are suggestive, and the tests may prove to be of value in investigation of suspected cases of leishmaniasis.


1 From the Medical Service, U. S. Marine Hospital, Wyman Park Drive and 31st St., Baltimore 11, Md.


2 Assistant Surgeon (Reserve) U. S. Public Health Service.


3 Surgeon, U. S. Public Health Service and Assistant Chief of Medical Service.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1948 by the American Society of Tropical Medicine and Hygiene.